AutismKB 2.0

Annotation Detail for KAT2B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:KAT2B ( CAF,P,P/CAF,PCAF )
Gene Full Name: K(lysine) acetyltransferase 2B
Band: 3p24.3
Quick LinksEntrez ID:8850; OMIM: 602303; Uniprot ID:KAT2B_HUMAN; ENSEMBL ID: ENSG00000114166; HGNC ID: 8638
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus36 / 56401263
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult68 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor4 / 26384515
glioma7 / 10688365
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal141 / 336030741
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood2 / 12347816
bone1 / 7165513
bone marrow1 / 4880120
brain51 / 110098946
cervix0 / 481710 
connective tissue4 / 14925526
ear2 / 16212123
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye11 / 21105452
heart0 / 896260 
intestine3 / 23447212
kidney7 / 21177733
larynx0 / 241450 
liver5 / 20774324
lung6 / 33697417
lymph0 / 442700 
lymph node4 / 9161043
mammary gland4 / 15327126
mouth0 / 670520 
muscle2 / 10771518
nerve3 / 15768190
ovary1 / 1020519
pancreas7 / 21481232
parathyroid2 / 2053997
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta14 / 28082549
prostate4 / 18934521
salivary gland1 / 2015549
skin7 / 21057433
spleen3 / 5395255
stomach3 / 9661931
testis4 / 33044212
thymus7 / 8113186
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus2 / 2328788
vascular11 / 51780212
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203845_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.85
Adipocyte8.95
AdrenalCortex12.65
Adrenalgland7.3
Amygdala102.15
Appendix22.9
AtrioventricularNode10.2
BDCA4+_DentriticCells93.05
Bonemarrow23.6
BronchialEpithelialCells7.4
CD105+_Endothelial280.8
CD14+_Monocytes50.4
CD19+_BCells(neg._sel.)74.9
CD33+_Myeloid39.35
CD34+16.1
CD4+_Tcells123.85
CD56+_NKCells256.8
CD71+_EarlyErythroid843.4
CD8+_Tcells201.95
CardiacMyocytes12.3
Caudatenucleus97.55
Cerebellum15.4
CerebellumPeduncles40.65
CiliaryGanglion13.05
CingulateCortex59.75
Colorectaladenocarcinoma7.8
DorsalRootGanglion13.35
FetalThyroid31.7
Fetalbrain13.35
Fetalliver114.85
Fetallung18.15
GlobusPallidus11.15
Heart12
Hypothalamus184.5
Kidney6.1
Leukemia_chronicMyelogenousK-5629.3
Leukemia_promyelocytic-HL-6010
Leukemialymphoblastic(MOLT-4)6.85
Liver13.65
Lung9.55
Lymphnode56.05
Lymphoma_burkitts(Daudi)22.95
Lymphoma_burkitts(Raji)13.65
MedullaOblongata59.7
OccipitalLobe79
OlfactoryBulb85.1
Ovary7.95
Pancreas7.75
PancreaticIslet17.65
ParietalLobe60.45
Pituitary37
Placenta9.95
Pons15.1
PrefrontalCortex164.15
Prostate18.45
Salivarygland23.2
SkeletalMuscle18.05
Skin6.8
SmoothMuscle9.15
Spinalcord136.5
SubthalamicNucleus42.7
SuperiorCervicalGanglion17.85
TemporalLobe10.2
Testis6.7
TestisGermCell6
TestisIntersitial6.6
TestisLeydigCell9.9
TestisSeminiferousTubule6.8
Thalamus73.35
Thymus15.65
Thyroid50
Tongue29.3
Tonsil18.3
Trachea8.85
TrigeminalGanglion14.9
Uterus28.45
UterusCorpus8.3
WholeBlood135.8
Wholebrain53.75
colon23.4
pineal_day149.7
pineal_night126.48
retina87.975
small_intestine26.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P41128
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.55 ± 0.54
Basal Forebrain8.83 ± 0.37
Basal Part of Pons7.77 ± 0.33
Cerebellar Cortex8.18 ± 0.25
Cerebellar Nuclei8.49 ± 0.43
Claustrum8.54 ± 0.23
Epithalamus8.4 ± 0.68
Frontal Lobe8.12 ± 0.51
Globus Pallidus9.94 ± 0.41
Hypothalamus8.21 ± 0.75
Insula8.1 ± 0.31
Limbic Lobe8.01 ± 0.56
Mesencephalon8.71 ± 0.45
Myelencephalon8.45 ± 0.58
Occipital Lobe8.74 ± 0.52
Parietal Lobe8.36 ± 0.5
Pontine Tegmentum8.57 ± 0.39
Striatum9.02 ± 0.58
Subthalamus8.56 ± 0.19
Temporal Lobe8.14 ± 0.42
Thalamus8.79 ± 0.36
White Matter9.9 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PcafCBCerebellum6.46
5.98
PcafCTXCerebral cortex0.54
0.57
PcafHIPHippocampal region0.28
0.29
PcafHPFHippocampal formation0.38
0.43
PcafHYHypothalamus0.28
0.15
PcafLSXLateral septal complex0.25
0.23
PcafMBMidbrain1.75
1.85
PcafMYMedulla4.11
2.99
PcafOLFOlfactory bulb0.89
0.52
PcafPPons1.85
0.91
PcafPALPallidum0.18
0.08
PcafRHPRetrohippocampal region0.53
0.63
PcafsAMYStriatum-like amygdalar nuclei0.36
0.24
PcafSTRStriatum0.15
0.12
PcafSTRdStriatum dorsal region0.09
0.06
PcafSTRvStriatum ventral region0.22
0.19
PcafTHThalamus0.69
0.89
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved