AutismKB 2.0

Annotation Detail for LDB1


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Basic Information Top
Gene Symbol:LDB1 ( CLIM2,NLI )
Gene Full Name: LIM domain binding 1
Band: 10q24.32
Quick LinksEntrez ID:8861; OMIM: 603451; Uniprot ID:LDB1_HUMAN; ENSEMBL ID: ENSG00000198728; HGNC ID: 6532
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus39 / 56401269
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma6 / 10688356
head and neck tumor6 / 13630244
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor11 / 103127106
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal88 / 336030726
ovarian tumor5 / 7668265
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer4 / 10268038
retinoblastoma2 / 4635643
skin tumor9 / 12494972
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder3 / 29757100
blood4 / 12347832
bone3 / 7165541
bone marrow1 / 4880120
brain19 / 110098917
cervix3 / 4817162
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye6 / 21105428
heart8 / 8962689
intestine8 / 23447234
kidney2 / 2117779
larynx1 / 2414541
liver2 / 2077439
lung21 / 33697462
lymph0 / 442700 
lymph node6 / 9161065
mammary gland6 / 15327139
mouth3 / 6705244
muscle4 / 10771537
nerve0 / 157680 
ovary5 / 10205148
pancreas7 / 21481232
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate4 / 18934521
salivary gland0 / 201550 
skin15 / 21057471
spleen0 / 539520 
stomach1 / 9661910
testis10 / 33044230
thymus3 / 8113136
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 35160_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.85
Adipocyte4.85
AdrenalCortex5.35
Adrenalgland4.15
Amygdala5.2
Appendix5.05
AtrioventricularNode3.9
BDCA4+_DentriticCells11.5
Bonemarrow4.85
BronchialEpithelialCells7.65
CD105+_Endothelial156.9
CD14+_Monocytes11.15
CD19+_BCells(neg._sel.)14.55
CD33+_Myeloid11.8
CD34+82.1
CD4+_Tcells15.85
CD56+_NKCells25.8
CD71+_EarlyErythroid25.4
CD8+_Tcells11
CardiacMyocytes6.25
Caudatenucleus4.4
Cerebellum4
CerebellumPeduncles5.6
CiliaryGanglion3.7
CingulateCortex5.05
Colorectaladenocarcinoma5.05
DorsalRootGanglion3.75
FetalThyroid4.8
Fetalbrain4.85
Fetalliver4.25
Fetallung4.2
GlobusPallidus3.75
Heart6.55
Hypothalamus5.25
Kidney3.95
Leukemia_chronicMyelogenousK-5624.7
Leukemia_promyelocytic-HL-604.45
Leukemialymphoblastic(MOLT-4)3.95
Liver6.45
Lung5.5
Lymphnode4.3
Lymphoma_burkitts(Daudi)6.15
Lymphoma_burkitts(Raji)7
MedullaOblongata4.45
OccipitalLobe4.4
OlfactoryBulb3.9
Ovary3.55
Pancreas4.1
PancreaticIslet5.3
ParietalLobe5.2
Pituitary5.7
Placenta5.15
Pons4.75
PrefrontalCortex5.9
Prostate5.7
Salivarygland3.95
SkeletalMuscle6.5
Skin3.8
SmoothMuscle5.65
Spinalcord5
SubthalamicNucleus4.5
SuperiorCervicalGanglion5.65
TemporalLobe4.5
Testis4.25
TestisGermCell4.15
TestisIntersitial4.25
TestisLeydigCell4.9
TestisSeminiferousTubule4.25
Thalamus5
Thymus3.95
Thyroid6.3
Tongue4.95
Tonsil4.8
Trachea4.1
TrigeminalGanglion5.15
Uterus4.1
UterusCorpus4.85
WholeBlood8.2
Wholebrain4.4
colon4.95
pineal_day7.26
pineal_night6.76
retina5.975
small_intestine4.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P97892
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.94 ± 0.39
Basal Forebrain5.86 ± 0.25
Basal Part of Pons5.68 ± 0.34
Cerebellar Cortex5.6 ± 0.23
Cerebellar Nuclei5.41 ± 0.6
Claustrum6.03 ± 0.55
Epithalamus5.58 ± 0.45
Frontal Lobe5.66 ± 0.36
Globus Pallidus5.31 ± 0.3
Hypothalamus5.64 ± 0.25
Insula5.77 ± 0.43
Limbic Lobe5.98 ± 0.36
Mesencephalon5.73 ± 0.37
Myelencephalon5.76 ± 0.42
Occipital Lobe5.99 ± 0.45
Parietal Lobe5.86 ± 0.31
Pontine Tegmentum5.76 ± 0.46
Striatum6.28 ± 0.37
Subthalamus5.71 ± 0.59
Temporal Lobe5.8 ± 0.31
Thalamus5.6 ± 0.39
White Matter5.32 ± 0.54
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00077534 18 175 192 SILAMHAQDPQMLDQLSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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