AutismKB 2.0

Annotation Detail for PER2


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Basic Information Top
Gene Symbol:PER2 ( FASPS,KIAA0347 )
Gene Full Name: period homolog 2 (Drosophila)
Band: 2q37.3
Quick LinksEntrez ID:8864; OMIM: 603426; Uniprot ID:PER2_HUMAN; ENSEMBL ID: ENSG00000132326; HGNC ID: 8846
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult45 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal57 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone1 / 7165513
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine1 / 2344724
kidney1 / 2117774
larynx8 / 24145331
liver5 / 20774324
lung6 / 33697417
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate5 / 18934526
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208518_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.15
Adipocyte4.05
AdrenalCortex4.3
Adrenalgland3.5
Amygdala4.3
Appendix4.15
AtrioventricularNode3.1
BDCA4+_DentriticCells4.6
Bonemarrow4.05
BronchialEpithelialCells4.05
CD105+_Endothelial4.1
CD14+_Monocytes4.4
CD19+_BCells(neg._sel.)4.4
CD33+_Myeloid5.25
CD34+5.1
CD4+_Tcells4.35
CD56+_NKCells4.9
CD71+_EarlyErythroid3.8
CD8+_Tcells3.9
CardiacMyocytes5.15
Caudatenucleus3.7
Cerebellum3.35
CerebellumPeduncles4.65
CiliaryGanglion2.8
CingulateCortex4.2
Colorectaladenocarcinoma4.1
DorsalRootGanglion3.1
FetalThyroid3.95
Fetalbrain4.1
Fetalliver3.55
Fetallung3.4
GlobusPallidus2.95
Heart5.3
Hypothalamus4.55
Kidney3.4
Leukemia_chronicMyelogenousK-5623.7
Leukemia_promyelocytic-HL-603.6
Leukemialymphoblastic(MOLT-4)3.3
Liver5.65
Lung4.55
Lymphnode3.55
Lymphoma_burkitts(Daudi)5.2
Lymphoma_burkitts(Raji)5.7
MedullaOblongata3.8
OccipitalLobe3.7
OlfactoryBulb3.2
Ovary2.7
Pancreas3.3
PancreaticIslet4.35
ParietalLobe4.3
Pituitary4.8
Placenta4.3
Pons3.9
PrefrontalCortex5.15
Prostate4.8
Salivarygland3.3
SkeletalMuscle4.9
Skin3.15
SmoothMuscle4.65
Spinalcord4.4
SubthalamicNucleus3.7
SuperiorCervicalGanglion4.6
TemporalLobe3.7
Testis3.55
TestisGermCell3.45
TestisIntersitial3.4
TestisLeydigCell4.05
TestisSeminiferousTubule3.55
Thalamus4.15
Thymus3.25
Thyroid5.2
Tongue4
Tonsil4
Trachea3.4
TrigeminalGanglion4.05
Uterus3.35
UterusCorpus3.7
WholeBlood4.5
Wholebrain3.55
colon4.15
pineal_day5.1
pineal_night5
retina4.95
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P411162
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.29 ± 0.37
Basal Forebrain5.03 ± 0.39
Basal Part of Pons5 ± 0.39
Cerebellar Cortex5.04 ± 0.38
Cerebellar Nuclei4.16 ± 0.55
Claustrum4.62 ± 0.6
Epithalamus5.26 ± 0.47
Frontal Lobe4.98 ± 0.44
Globus Pallidus4.11 ± 0.45
Hypothalamus4.98 ± 0.68
Insula5.13 ± 0.34
Limbic Lobe5.19 ± 0.49
Mesencephalon4.91 ± 0.51
Myelencephalon5 ± 0.51
Occipital Lobe5.41 ± 0.45
Parietal Lobe5.04 ± 0.34
Pontine Tegmentum4.89 ± 0.55
Striatum5.18 ± 0.49
Subthalamus4.63 ± 0.26
Temporal Lobe5 ± 0.51
Thalamus4.68 ± 0.47
White Matter4.14 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Per2CBCerebellum90.64
81.05
Per2CTXCerebral cortex90.59
81.43
Per2HIPHippocampal region70.45
58.71
Per2HPFHippocampal formation73.77
62.92
Per2HYHypothalamus34.59
28.12
Per2LSXLateral septal complex38.34
23.46
Per2MBMidbrain28.53
22.4
Per2MYMedulla63.63
60.88
Per2OLFOlfactory bulb92.7
78.4
Per2PPons40.48
36.09
Per2PALPallidum25.16
19.6
Per2RHPRetrohippocampal region77.1
65.54
Per2sAMYStriatum-like amygdalar nuclei34.53
22.5
Per2STRStriatum64.93
44.85
Per2STRdStriatum dorsal region69.96
48.49
Per2STRvStriatum ventral region78.68
56.42
Per2THThalamus26.21
19.81
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018