AutismKB 2.0

Annotation Detail for VNN1


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Basic Information Top
Gene Symbol:VNN1 ( HDLCQ8,MGC116930,MGC116931,MGC116932,MGC116933,Tiff66 )
Gene Full Name: vanin 1
Band: 6q23.2
Quick LinksEntrez ID:8876; OMIM: 603570; Uniprot ID:VNN1_HUMAN; ENSEMBL ID: ENSG00000112299; HGNC ID: 12705
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate3 / 3109796
infant0 / 236200 
juvenile0 / 555560 
adult17 / 19391218
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult3 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal31 / 33603079
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal6 / 33603071
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood9 / 12347872
bone1 / 7165513
bone marrow2 / 4880140
brain0 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney11 / 21177751
larynx0 / 241450 
liver9 / 20774343
lung2 / 3369745
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach2 / 9661920
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205844_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.95
Adipocyte7.35
AdrenalCortex9.8
Adrenalgland6.85
Amygdala7.35
Appendix11.8
AtrioventricularNode7.9
BDCA4+_DentriticCells7.8
Bonemarrow11.9
BronchialEpithelialCells7.1
CD105+_Endothelial7.45
CD14+_Monocytes211.75
CD19+_BCells(neg._sel.)7.6
CD33+_Myeloid98.4
CD34+8.8
CD4+_Tcells7.4
CD56+_NKCells8.4
CD71+_EarlyErythroid7.35
CD8+_Tcells6.55
CardiacMyocytes13.8
Caudatenucleus6.85
Cerebellum6.35
CerebellumPeduncles9.5
CiliaryGanglion7.3
CingulateCortex8
Colorectaladenocarcinoma7.55
DorsalRootGanglion7.05
FetalThyroid7.75
Fetalbrain7.05
Fetalliver7.1
Fetallung6.6
GlobusPallidus6.2
Heart12.85
Hypothalamus7.65
Kidney7.2
Leukemia_chronicMyelogenousK-5626.75
Leukemia_promyelocytic-HL-606.7
Leukemialymphoblastic(MOLT-4)5.7
Liver11.9
Lung8.25
Lymphnode6.2
Lymphoma_burkitts(Daudi)10.1
Lymphoma_burkitts(Raji)12
MedullaOblongata6.75
OccipitalLobe6.65
OlfactoryBulb5.9
Ovary6.1
Pancreas6.45
PancreaticIslet9.85
ParietalLobe8.9
Pituitary8.75
Placenta7.35
Pons7.7
PrefrontalCortex8.65
Prostate8.45
Salivarygland7.6
SkeletalMuscle12.25
Skin7.25
SmoothMuscle8.4
Spinalcord8.05
SubthalamicNucleus7.4
SuperiorCervicalGanglion16.25
TemporalLobe7.2
Testis6.5
TestisGermCell6
TestisIntersitial6.55
TestisLeydigCell7.9
TestisSeminiferousTubule6.45
Thalamus7.95
Thymus5.55
Thyroid8.75
Tongue8.75
Tonsil7.55
Trachea6.3
TrigeminalGanglion9.8
Uterus5.85
UterusCorpus8
WholeBlood73
Wholebrain5.75
colon7.5
pineal_day9.12
pineal_night9.02
retina9.05
small_intestine94.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P255345
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.97 ± 1.02
Basal Forebrain1.49 ± 0.21
Basal Part of Pons1.12 ± 0.33
Cerebellar Cortex1.42 ± 0.74
Cerebellar Nuclei1.82 ± 0.74
Claustrum2.19 ± 0.62
Epithalamus1.24 ± 0.77
Frontal Lobe1.34 ± 0.61
Globus Pallidus1.98 ± 0.39
Hypothalamus1.66 ± 0.87
Insula1.49 ± 0.55
Limbic Lobe1.49 ± 0.62
Mesencephalon1.66 ± 0.66
Myelencephalon1.53 ± 0.63
Occipital Lobe1.5 ± 0.56
Parietal Lobe1.51 ± 0.77
Pontine Tegmentum1.63 ± 0.75
Striatum1.79 ± 0.85
Subthalamus1.72 ± 0.66
Temporal Lobe1.44 ± 0.68
Thalamus1.5 ± 0.58
White Matter2.01 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Vnn1CBCerebellum2.72
2.89
Vnn1CTXCerebral cortex6.07
4.82
Vnn1HIPHippocampal region4.2
3.67
Vnn1HPFHippocampal formation4.11
3.21
Vnn1HYHypothalamus0.04
0.05
Vnn1LSXLateral septal complex0.28
0.3
Vnn1MBMidbrain0.58
0.78
Vnn1MYMedulla1.33
1.59
Vnn1OLFOlfactory bulb4.11
3.59
Vnn1PPons0.56
1
Vnn1PALPallidum0.97
0.85
Vnn1RHPRetrohippocampal region4.14
2.7
Vnn1sAMYStriatum-like amygdalar nuclei2.52
2.03
Vnn1STRStriatum1.31
1.05
Vnn1STRdStriatum dorsal region1.43
1.16
Vnn1STRvStriatum ventral region0.35
0.31
Vnn1THThalamus0.45
0.53
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00026732 13 347 359 LTGVAGNYTVCQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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