AutismKB 2.0

Annotation Detail for AP1G2


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Basic Information Top
Gene Symbol:AP1G2 ( G2AD )
Gene Full Name: adaptor-related protein complex 1, gamma 2 subunit
Band: 14q11.2
Quick LinksEntrez ID:8906; OMIM: 603534; Uniprot ID:AP1G2_HUMAN; ENSEMBL ID: ENSG00000213983; HGNC ID: 556
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst2 / 6231932
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult122 / 193912162
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma3 / 8282336
colorectal tumor12 / 114246105
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor8 / 26384530
glioma1 / 1068839
head and neck tumor6 / 13630244
kidney tumor6 / 6895987
leukemia16 / 95842166
liver tumor1 / 9635910
lung tumor6 / 10312758
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal164 / 336030748
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer9 / 10268087
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood13 / 123478105
bone4 / 7165555
bone marrow2 / 4880140
brain26 / 110098923
cervix8 / 48171166
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye4 / 21105418
heart1 / 8962611
intestine21 / 23447289
kidney13 / 21177761
larynx2 / 2414582
liver8 / 20774338
lung14 / 33697441
lymph2 / 4427045
lymph node11 / 91610120
mammary gland10 / 15327165
mouth1 / 6705214
muscle2 / 10771518
nerve1 / 1576863
ovary7 / 10205168
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta25 / 28082589
prostate22 / 189345116
salivary gland0 / 201550 
skin5 / 21057423
spleen2 / 5395237
stomach3 / 9661931
testis3 / 3304429
thymus11 / 81131135
thyroid4 / 4747384
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord0 / 136800 
uterus20 / 23287885
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201613_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts55.85
Adipocyte6.55
AdrenalCortex20.25
Adrenalgland15.85
Amygdala17.65
Appendix9.4
AtrioventricularNode5.8
BDCA4+_DentriticCells105.7
Bonemarrow18.95
BronchialEpithelialCells21
CD105+_Endothelial19.1
CD14+_Monocytes29.8
CD19+_BCells(neg._sel.)148.45
CD33+_Myeloid65.85
CD34+105.9
CD4+_Tcells187.45
CD56+_NKCells71.35
CD71+_EarlyErythroid6.2
CD8+_Tcells178.45
CardiacMyocytes16.95
Caudatenucleus23.5
Cerebellum15.3
CerebellumPeduncles25
CiliaryGanglion6.25
CingulateCortex19.6
Colorectaladenocarcinoma35.35
DorsalRootGanglion5.4
FetalThyroid24.3
Fetalbrain33.65
Fetalliver9.55
Fetallung18.05
GlobusPallidus11.4
Heart24.8
Hypothalamus20.85
Kidney14.55
Leukemia_chronicMyelogenousK-56217.05
Leukemia_promyelocytic-HL-6034.3
Leukemialymphoblastic(MOLT-4)46.65
Liver18.95
Lung19.9
Lymphnode61.45
Lymphoma_burkitts(Daudi)54.8
Lymphoma_burkitts(Raji)38.4
MedullaOblongata21.2
OccipitalLobe19.05
OlfactoryBulb14.45
Ovary11.55
Pancreas20.9
PancreaticIslet19.3
ParietalLobe19.15
Pituitary29.15
Placenta19.1
Pons17.3
PrefrontalCortex75.1
Prostate24.4
Salivarygland15.85
SkeletalMuscle21.6
Skin14.5
SmoothMuscle9
Spinalcord15.25
SubthalamicNucleus11.45
SuperiorCervicalGanglion14.15
TemporalLobe11.65
Testis15.05
TestisGermCell12.45
TestisIntersitial7.1
TestisLeydigCell15.05
TestisSeminiferousTubule14.75
Thalamus12.9
Thymus47.2
Thyroid18.6
Tongue20.8
Tonsil56.95
Trachea14.2
TrigeminalGanglion7.1
Uterus14.6
UterusCorpus13.95
WholeBlood35.65
Wholebrain7
colon20.65
pineal_day21.42
pineal_night16.56
retina13.775
small_intestine18.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14894_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.49 ± 0.49
Basal Forebrain5.11 ± 0.42
Basal Part of Pons4.87 ± 0.68
Cerebellar Cortex5.25 ± 0.4
Cerebellar Nuclei4.31 ± 0.59
Claustrum5.1 ± 0.77
Epithalamus4.49 ± 0.63
Frontal Lobe4.51 ± 0.64
Globus Pallidus3.44 ± 0.92
Hypothalamus4.46 ± 0.66
Insula4.81 ± 0.81
Limbic Lobe5.38 ± 0.74
Mesencephalon4.74 ± 0.68
Myelencephalon4.77 ± 0.65
Occipital Lobe5.47 ± 0.72
Parietal Lobe4.87 ± 0.68
Pontine Tegmentum4.85 ± 0.79
Striatum5.78 ± 0.64
Subthalamus4.17 ± 0.56
Temporal Lobe4.88 ± 0.58
Thalamus4.32 ± 0.63
White Matter4.01 ± 0.45
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ap1g2CBCerebellum2.76
3.79
Ap1g2CTXCerebral cortex3.19
2.26
Ap1g2HIPHippocampal region5.04
3.98
Ap1g2HPFHippocampal formation5.67
4.18
Ap1g2HYHypothalamus0.42
0.36
Ap1g2LSXLateral septal complex0.5
0.55
Ap1g2MBMidbrain1.39
1.64
Ap1g2MYMedulla2.73
2.71
Ap1g2OLFOlfactory bulb4.53
3.38
Ap1g2PPons2.95
3.65
Ap1g2PALPallidum0.77
1.26
Ap1g2RHPRetrohippocampal region6.47
4.29
Ap1g2sAMYStriatum-like amygdalar nuclei4.2
2.26
Ap1g2STRStriatum1.1
0.68
Ap1g2STRdStriatum dorsal region0.59
0.37
Ap1g2STRvStriatum ventral region0.91
0.71
Ap1g2THThalamus0.86
1.02
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
AP1G2_HUMAN_2 15 2 16 VVPSLKLQDLIEEIR PRIDE
PAp00026327 20 168 187 KVPELSSVFLPPCAQLLHER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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