AutismKB 2.0

Annotation Detail for WASF1


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Basic Information Top
Gene Symbol:WASF1 ( FLJ31482,KIAA0269,SCAR1,WAVE,WAVE1 )
Gene Full Name: WAS protein family, member 1
Band: 6q21
Quick LinksEntrez ID:8936; OMIM: 605035; Uniprot ID:WASF1_HUMAN; ENSEMBL ID: ENSG00000112290; HGNC ID: 12732
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst3 / 6231948
fetus145 / 564012257
neonate5 / 31097160
infant4 / 23620169
juvenile8 / 55556143
adult70 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor45 / 263845170
glioma0 / 1068830 
head and neck tumor6 / 13630244
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma3 / 7175541
non-neoplasia6 / 9725061
normal331 / 336030798
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS18 / 125680143
prostate cancer1 / 1026809
retinoblastoma4 / 4635686
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder3 / 29757100
blood5 / 12347840
bone6 / 7165583
bone marrow0 / 488010 
brain270 / 1100989245
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine3 / 23447212
kidney7 / 21177733
larynx0 / 241450 
liver1 / 2077434
lung6 / 33697417
lymph3 / 4427067
lymph node0 / 916100 
mammary gland1 / 1532716
mouth7 / 67052104
muscle4 / 10771537
nerve2 / 15768126
ovary4 / 10205139
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate1 / 1893455
salivary gland1 / 2015549
skin7 / 21057433
spleen0 / 539520 
stomach2 / 9661920
testis82 / 330442248
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204165_at
Cell line Expression level Expression bar
721_B_lymphoblasts50.25
Adipocyte16.65
AdrenalCortex18.7
Adrenalgland15.15
Amygdala1242.8
Appendix20.8
AtrioventricularNode15.05
BDCA4+_DentriticCells23.2
Bonemarrow15.8
BronchialEpithelialCells30.8
CD105+_Endothelial18.75
CD14+_Monocytes10.3
CD19+_BCells(neg._sel.)16.2
CD33+_Myeloid15.35
CD34+54.85
CD4+_Tcells9.45
CD56+_NKCells9.75
CD71+_EarlyErythroid18.25
CD8+_Tcells8.2
CardiacMyocytes26.35
Caudatenucleus321.8
Cerebellum111.8
CerebellumPeduncles54.6
CiliaryGanglion15.9
CingulateCortex223.4
Colorectaladenocarcinoma18.6
DorsalRootGanglion28.65
FetalThyroid9.25
Fetalbrain734.15
Fetalliver16.35
Fetallung14.25
GlobusPallidus125.35
Heart18.7
Hypothalamus127.55
Kidney14.55
Leukemia_chronicMyelogenousK-56219.85
Leukemia_promyelocytic-HL-6046.15
Leukemialymphoblastic(MOLT-4)30.6
Liver15.5
Lung10.7
Lymphnode13.7
Lymphoma_burkitts(Daudi)34.65
Lymphoma_burkitts(Raji)45.1
MedullaOblongata221.15
OccipitalLobe222.3
OlfactoryBulb17.65
Ovary11.75
Pancreas9.6
PancreaticIslet18.15
ParietalLobe136.65
Pituitary23.1
Placenta11.75
Pons110.6
PrefrontalCortex882.9
Prostate12.05
Salivarygland15.7
SkeletalMuscle22.9
Skin20.35
SmoothMuscle18
Spinalcord75.1
SubthalamicNucleus140.25
SuperiorCervicalGanglion37.2
TemporalLobe100.05
Testis228.2
TestisGermCell122.2
TestisIntersitial33.55
TestisLeydigCell55.5
TestisSeminiferousTubule61.45
Thalamus93.9
Thymus9.3
Thyroid10.9
Tongue17.65
Tonsil13.4
Trachea12.65
TrigeminalGanglion17.85
Uterus24.95
UterusCorpus18.6
WholeBlood9.4
Wholebrain728.5
colon19.15
pineal_day24.84
pineal_night22.18
retina29.625
small_intestine22.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10915_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.27 ± 0.5
Basal Forebrain4.68 ± 0.49
Basal Part of Pons5.34 ± 0.33
Cerebellar Cortex4.48 ± 0.45
Cerebellar Nuclei3.97 ± 0.38
Claustrum5.4 ± 0.64
Epithalamus3.71 ± 0.78
Frontal Lobe4.66 ± 0.61
Globus Pallidus3.15 ± 0.81
Hypothalamus4.16 ± 0.78
Insula4.81 ± 0.48
Limbic Lobe5.53 ± 0.69
Mesencephalon4.49 ± 0.67
Myelencephalon4.78 ± 0.67
Occipital Lobe5.32 ± 0.63
Parietal Lobe4.94 ± 0.68
Pontine Tegmentum4.68 ± 0.71
Striatum5.66 ± 0.47
Subthalamus4.17 ± 0.34
Temporal Lobe4.96 ± 0.55
Thalamus4.59 ± 0.43
White Matter3.76 ± 0.97
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00069525 9 12 20 HLCHTALPR Peptide Atlas
WASF1_HUMAN_0 0 0 0 SVLLEAIRK PRIDE
WASF1_HUMAN_498 9 498 506 SVLLEAIRK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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