AutismKB 2.0

Annotation Detail for CCND2


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Basic Information Top
Gene Symbol:CCND2 ( KIAK0002,MGC102758 )
Gene Full Name: cyclin D2
Band: 12p13.32
Quick LinksEntrez ID:894; OMIM: 123833; Uniprot ID:CCND2_HUMAN; ENSEMBL ID: ENSG00000118971; HGNC ID: 1583
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body30 / 70761423
blastocyst12 / 62319192
fetus80 / 564012141
neonate3 / 3109796
infant1 / 2362042
juvenile3 / 5555653
adult252 / 1939121129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor33 / 114246288
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor44 / 263845166
glioma20 / 106883187
head and neck tumor23 / 136302168
kidney tumor7 / 68959101
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor3 / 10312729
lymphoma2 / 7175527
non-neoplasia6 / 9725061
normal321 / 336030795
ovarian tumor9 / 76682117
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer12 / 102680116
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland7 / 33197210
ascites0 / 400150 
bladder5 / 29757168
blood14 / 123478113
bone4 / 7165555
bone marrow4 / 4880181
brain120 / 1100989108
cervix1 / 4817120
connective tissue8 / 14925553
ear4 / 16212246
embryonic tissue53 / 215722245
esophagus1 / 2020949
eye19 / 21105490
heart18 / 89626200
intestine40 / 234472170
kidney13 / 21177761
larynx3 / 24145124
liver4 / 20774319
lung24 / 33697471
lymph1 / 4427022
lymph node4 / 9161043
mammary gland0 / 1532710 
mouth3 / 6705244
muscle24 / 107715222
nerve3 / 15768190
ovary8 / 10205178
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx3 / 4132872
pituitary gland2 / 16585120
placenta25 / 28082589
prostate16 / 18934584
salivary gland0 / 201550 
skin6 / 21057428
spleen6 / 53952111
stomach9 / 9661993
testis30 / 33044290
thymus7 / 8113186
thyroid19 / 47473400
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord2 / 13680146
uterus17 / 23287872
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200952_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts72.5
Adipocyte4.7
AdrenalCortex4.85
Adrenalgland5.85
Amygdala5.05
Appendix5
AtrioventricularNode3.65
BDCA4+_DentriticCells5.35
Bonemarrow4.6
BronchialEpithelialCells6.35
CD105+_Endothelial4.9
CD14+_Monocytes5.1
CD19+_BCells(neg._sel.)5.05
CD33+_Myeloid6.1
CD34+6.15
CD4+_Tcells8.3
CD56+_NKCells7.15
CD71+_EarlyErythroid4.4
CD8+_Tcells4.7
CardiacMyocytes5.95
Caudatenucleus4.25
Cerebellum3.8
CerebellumPeduncles5.35
CiliaryGanglion3.45
CingulateCortex4.85
Colorectaladenocarcinoma4.75
DorsalRootGanglion3.6
FetalThyroid4.6
Fetalbrain4.8
Fetalliver4.05
Fetallung3.8
GlobusPallidus3.5
Heart5.95
Hypothalamus5.15
Kidney3.8
Leukemia_chronicMyelogenousK-5624.3
Leukemia_promyelocytic-HL-604.05
Leukemialymphoblastic(MOLT-4)3.65
Liver6.15
Lung5.25
Lymphnode4.15
Lymphoma_burkitts(Daudi)6
Lymphoma_burkitts(Raji)6.55
MedullaOblongata4.45
OccipitalLobe4.25
OlfactoryBulb3.75
Ovary3.1
Pancreas3.8
PancreaticIslet5.05
ParietalLobe4.95
Pituitary5.5
Placenta5
Pons5.45
PrefrontalCortex6
Prostate5.55
Salivarygland3.8
SkeletalMuscle5.4
Skin3.9
SmoothMuscle5.35
Spinalcord5.05
SubthalamicNucleus4.25
SuperiorCervicalGanglion5.6
TemporalLobe4.3
Testis4.1
TestisGermCell3.95
TestisIntersitial4
TestisLeydigCell4.65
TestisSeminiferousTubule4.1
Thalamus4.7
Thymus3.8
Thyroid5.85
Tongue4.55
Tonsil4.6
Trachea3.95
TrigeminalGanglion6.95
Uterus3.95
UterusCorpus5.05
WholeBlood5.3
Wholebrain4.05
colon7.25
pineal_day5.96
pineal_night5.74
retina5.55
small_intestine8.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P270235
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.49 ± 0.78
Basal Forebrain8.28 ± 0.15
Basal Part of Pons8.56 ± 0.56
Cerebellar Cortex7.7 ± 0.33
Cerebellar Nuclei8.11 ± 0.68
Claustrum7.63 ± 0.85
Epithalamus8.2 ± 0.79
Frontal Lobe8.42 ± 0.73
Globus Pallidus7.01 ± 0.65
Hypothalamus7.76 ± 0.52
Insula8.3 ± 0.3
Limbic Lobe8.24 ± 0.77
Mesencephalon7.7 ± 0.49
Myelencephalon8.06 ± 0.66
Occipital Lobe7.59 ± 0.67
Parietal Lobe8.24 ± 0.63
Pontine Tegmentum8.06 ± 0.65
Striatum7.37 ± 0.92
Subthalamus7.43 ± 0.58
Temporal Lobe8.44 ± 0.49
Thalamus7.71 ± 0.52
White Matter6.29 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ccnd2CBCerebellum1.67
3.18
Ccnd2CTXCerebral cortex1.77
2.34
Ccnd2HIPHippocampal region24.79
32.37
Ccnd2HPFHippocampal formation15.7
18.19
Ccnd2HYHypothalamus0.45
0.56
Ccnd2LSXLateral septal complex6.55
20.09
Ccnd2MBMidbrain1.22
1.83
Ccnd2MYMedulla2.14
4.75
Ccnd2OLFOlfactory bulb6.29
7.29
Ccnd2PPons0.59
0.71
Ccnd2PALPallidum0.37
0.49
Ccnd2RHPRetrohippocampal region5.01
4.17
Ccnd2sAMYStriatum-like amygdalar nuclei1.61
2.94
Ccnd2STRStriatum4.88
7.46
Ccnd2STRdStriatum dorsal region5.13
6.52
Ccnd2STRvStriatum ventral region1.91
1.4
Ccnd2THThalamus0.98
1.54
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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