Annotation Detail for AP3D1
Basic Information Top
| Gene Symbol: | AP3D1 ( ADTD,hBLVR ) |
|---|---|
| Gene Full Name: | adaptor-related protein complex 3, delta 1 subunit |
| Band: | 19p13.3 |
| Quick Links | Entrez ID:8943; OMIM: 607246; Uniprot ID:AP3D1_HUMAN; ENSEMBL ID: ENSG00000065000; HGNC ID: 568 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.512815
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 11 / 70761 | 155 |  |
| blastocyst | 8 / 62319 | 128 | |
| fetus | 33 / 564012 | 58 | |
| neonate | 2 / 31097 | 64 | |
| infant | 3 / 23620 | 127 | |
| juvenile | 3 / 55556 | 53 | |
| adult | 208 / 1939121 | 107 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 3 / 17475 | 171 | |
| breast (mammary gland) tumor | 6 / 94178 | 63 | |
| cervical tumor | 4 / 34366 | 116 | |
| chondrosarcoma | 14 / 82823 | 169 | |
| colorectal tumor | 16 / 114246 | 140 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 19 / 119369 | 159 | |
| germ cell tumor | 36 / 263845 | 136 | |
| glioma | 11 / 106883 | 102 | |
| head and neck tumor | 10 / 136302 | 73 | |
| kidney tumor | 12 / 68959 | 174 | |
| leukemia | 3 / 95842 | 31 |  |
| liver tumor | 8 / 96359 | 83 | |
| lung tumor | 35 / 103127 | 339 |  |
| lymphoma | 14 / 71755 | 195 | |
| non-neoplasia | 5 / 97250 | 51 | |
| normal | 288 / 3360307 | 85 | |
| ovarian tumor | 10 / 76682 | 130 | |
| pancreatic tumor | 19 / 104616 | 181 | |
| primitive neuroectodermal tumor of the CNS | 15 / 125680 | 119 | |
| prostate cancer | 26 / 102680 | 253 | |
| retinoblastoma | 15 / 46356 | 323 | |
| skin tumor | 50 / 124949 | 400 | |
| soft tissue/muscle tissue tumor | 30 / 125191 | 239 | |
| uterine tumor | 16 / 90257 | 177 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 3 / 13106 | 228 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 7 / 40015 | 174 | |
| bladder | 3 / 29757 | 100 | |
| blood | 2 / 123478 | 16 | |
| bone | 13 / 71655 | 181 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 63 / 1100989 | 57 | |
| cervix | 5 / 48171 | 103 | |
| connective tissue | 7 / 149255 | 46 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 32 / 215722 | 148 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 40 / 211054 | 189 | |
| heart | 6 / 89626 | 66 | |
| intestine | 40 / 234472 | 170 | |
| kidney | 22 / 211777 | 103 | |
| larynx | 1 / 24145 | 41 | |
| liver | 13 / 207743 | 62 | |
| lung | 56 / 336974 | 166 | |
| lymph | 8 / 44270 | 180 | |
| lymph node | 5 / 91610 | 54 | |
| mammary gland | 12 / 153271 | 78 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 21 / 107715 | 194 | |
| nerve | 3 / 15768 | 190 | |
| ovary | 23 / 102051 | 225 | |
| pancreas | 28 / 214812 | 130 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 3 / 16585 | 180 | |
| placenta | 13 / 280825 | 46 | |
| prostate | 32 / 189345 | 169 | |
| salivary gland | 3 / 20155 | 148 | |
| skin | 58 / 210574 | 275 | |
| spleen | 4 / 53952 | 74 | |
| stomach | 9 / 96619 | 93 | |
| testis | 28 / 330442 | 84 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 4 / 47473 | 84 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 33 / 232878 | 141 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 210974_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 13.15 | |
| Adipocyte | 4.55 |  |
| AdrenalCortex | 4.8 | |
| Adrenalgland | 3.8 | |
| Amygdala | 4.85 | |
| Appendix | 4.55 | |
| AtrioventricularNode | 3.5 | |
| BDCA4+_DentriticCells | 32.7 | |
| Bonemarrow | 4.5 | |
| BronchialEpithelialCells | 4.5 | |
| CD105+_Endothelial | 4.7 | |
| CD14+_Monocytes | 5.35 | |
| CD19+_BCells(neg._sel.) | 5.65 | |
| CD33+_Myeloid | 9.1 | |
| CD34+ | 9 | |
| CD4+_Tcells | 8.2 | |
| CD56+_NKCells | 26.3 | |
| CD71+_EarlyErythroid | 4.3 | |
| CD8+_Tcells | 5.4 | |
| CardiacMyocytes | 5.9 | |
| Caudatenucleus | 4.1 | |
| Cerebellum | 3.7 | |
| CerebellumPeduncles | 5.15 | |
| CiliaryGanglion | 3.2 | |
| CingulateCortex | 4.65 | |
| Colorectaladenocarcinoma | 4.6 | |
| DorsalRootGanglion | 3.5 | |
| FetalThyroid | 4.4 | |
| Fetalbrain | 4.5 | |
| Fetalliver | 4 | |
| Fetallung | 3.8 | |
| GlobusPallidus | 3.35 | |
| Heart | 5.95 | |
| Hypothalamus | 5 | |
| Kidney | 3.7 | |
| Leukemia_chronicMyelogenousK-562 | 4.15 | |
| Leukemia_promyelocytic-HL-60 | 4.05 | |
| Leukemialymphoblastic(MOLT-4) | 3.7 | |
| Liver | 6.1 | |
| Lung | 5.1 | |
| Lymphnode | 3.9 | |
| Lymphoma_burkitts(Daudi) | 5.8 | |
| Lymphoma_burkitts(Raji) | 6.6 | |
| MedullaOblongata | 4.15 | |
| OccipitalLobe | 4.1 | |
| OlfactoryBulb | 3.6 | |
| Ovary | 3.05 | |
| Pancreas | 3.7 | |
| PancreaticIslet | 4.9 | |
| ParietalLobe | 4.8 | |
| Pituitary | 5.3 | |
| Placenta | 4.75 | |
| Pons | 4.3 | |
| PrefrontalCortex | 5.65 | |
| Prostate | 6.7 | |
| Salivarygland | 3.6 | |
| SkeletalMuscle | 5.3 | |
| Skin | 3.5 | |
| SmoothMuscle | 5.2 | |
| Spinalcord | 4.9 | |
| SubthalamicNucleus | 4.15 | |
| SuperiorCervicalGanglion | 5.15 | |
| TemporalLobe | 4.15 | |
| Testis | 3.9 | |
| TestisGermCell | 3.75 | |
| TestisIntersitial | 3.85 | |
| TestisLeydigCell | 4.5 | |
| TestisSeminiferousTubule | 3.9 | |
| Thalamus | 4.65 | |
| Thymus | 3.55 | |
| Thyroid | 5.8 | |
| Tongue | 4.4 | |
| Tonsil | 4.45 | |
| Trachea | 3.85 | |
| TrigeminalGanglion | 4.55 | |
| Uterus | 3.7 | |
| UterusCorpus | 4.05 | |
| WholeBlood | 4.95 | |
| Wholebrain | 3.95 | |
| colon | 4.65 | |
| pineal_day | 5.78 | |
| pineal_night | 5.66 | |
| retina | 5.475 | |
| small_intestine | 4.45 | |
- Probe name: A_23_P108135
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 12.91 ± 0.26 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 12.8 ± 0.21 | |
| Basal Part of Pons | 12.93 ± 0.2 | |
| Cerebellar Cortex | 12.75 ± 0.18 | |
| Cerebellar Nuclei | 12.53 ± 0.37 | |
| Claustrum | 13.06 ± 0.31 | |
| Epithalamus | 12.56 ± 0.21 | |
| Frontal Lobe | 12.84 ± 0.26 | |
| Globus Pallidus | 12.61 ± 0.3 | |
| Hypothalamus | 12.72 ± 0.18 | |
| Insula | 12.92 ± 0.14 | |
| Limbic Lobe | 13.11 ± 0.22 | |
| Mesencephalon | 12.86 ± 0.27 | |
| Myelencephalon | 12.89 ± 0.26 | |
| Occipital Lobe | 13.05 ± 0.23 | |
| Parietal Lobe | 12.9 ± 0.24 | |
| Pontine Tegmentum | 12.8 ± 0.27 | |
| Striatum | 13.19 ± 0.24 | |
| Subthalamus | 12.61 ± 0.12 | |
| Temporal Lobe | 12.94 ± 0.2 | |
| Thalamus | 12.91 ± 0.23 | |
| White Matter | 12.57 ± 0.26 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ap3d1 | CB | Cerebellum | 48.66 | |
| 61.46 | | |||
| Ap3d1 | CTX | Cerebral cortex | 100 | |
| 94.62 | | |||
| Ap3d1 | HIP | Hippocampal region | 75.89 | |
| 100 | | |||
| Ap3d1 | HPF | Hippocampal formation | 86.55 | |
| 100 | | |||
| Ap3d1 | HY | Hypothalamus | 62.77 | |
| 52.1 | | |||
| Ap3d1 | LSX | Lateral septal complex | 77.46 | |
| 59.29 | | |||
| Ap3d1 | MB | Midbrain | 55.94 | |
| 50.23 | | |||
| Ap3d1 | MY | Medulla | 44.99 | |
| 47.28 | | |||
| Ap3d1 | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Ap3d1 | P | Pons | 47.44 | |
| 45.64 | | |||
| Ap3d1 | PAL | Pallidum | 68.06 | |
| 62.34 | | |||
| Ap3d1 | RHP | Retrohippocampal region | 100 | |
| 96.99 | | |||
| Ap3d1 | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 89.79 | | |||
| Ap3d1 | STR | Striatum | 74.64 | |
| 57.34 | | |||
| Ap3d1 | STRd | Striatum dorsal region | 69.44 | |
| 53 | | |||
| Ap3d1 | STRv | Striatum ventral region | 79.62 | |
| 57 | | |||
| Ap3d1 | TH | Thalamus | 81.79 | |
| 70.3 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| AP3D1_HUMAN_2 | 11 | 2 | 12 | ALKMVKGSIDR | PRIDE |
| AP3D1_HUMAN_588 | 22 | 588 | 609 | DVPVAEEVSALFAGELNPVAPK | PRIDE |
| PAp00001347 | 15 | 1133 | 1147 | CSDSTLLSNLLEEMK | Peptide Atlas |