AutismKB 2.0

Annotation Detail for BTRC


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Basic Information Top
Gene Symbol:BTRC ( BETA-TRCP,FBW1A,FBXW1,FBXW1A,FWD1,MGC4643,bTrCP,bTrCP1,betaTrCP )
Gene Full Name: beta-transducin repeat containing
Band: 10q24.32
Quick LinksEntrez ID:8945; OMIM: 603482; Uniprot ID:FBW1A_HUMAN; ENSEMBL ID: ENSG00000166167; HGNC ID: 1144
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst4 / 6231964
fetus47 / 56401283
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult77 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor9 / 9417895
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor15 / 26384556
glioma4 / 10688337
head and neck tumor2 / 13630214
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal161 / 336030747
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer5 / 10268048
retinoblastoma5 / 46356107
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone6 / 7165583
bone marrow0 / 488010 
brain62 / 110098956
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus1 / 2020949
eye13 / 21105461
heart3 / 8962633
intestine4 / 23447217
kidney6 / 21177728
larynx0 / 241450 
liver0 / 2077430 
lung10 / 33697429
lymph1 / 4427022
lymph node3 / 9161032
mammary gland10 / 15327165
mouth2 / 6705229
muscle13 / 107715120
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta4 / 28082514
prostate8 / 18934542
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis17 / 33044251
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216091_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.6
Adipocyte3.5
AdrenalCortex3.6
Adrenalgland2.95
Amygdala3.8
Appendix3.55
AtrioventricularNode2.7
BDCA4+_DentriticCells4
Bonemarrow3.5
BronchialEpithelialCells3.55
CD105+_Endothelial3.6
CD14+_Monocytes3.8
CD19+_BCells(neg._sel.)3.85
CD33+_Myeloid4.6
CD34+4.6
CD4+_Tcells4
CD56+_NKCells4.35
CD71+_EarlyErythroid11.3
CD8+_Tcells3.55
CardiacMyocytes4.55
Caudatenucleus3.15
Cerebellum2.85
CerebellumPeduncles4
CiliaryGanglion2.45
CingulateCortex3.6
Colorectaladenocarcinoma3.55
DorsalRootGanglion2.65
FetalThyroid3.5
Fetalbrain3.55
Fetalliver3.2
Fetallung2.95
GlobusPallidus2.6
Heart4.55
Hypothalamus3.9
Kidney2.85
Leukemia_chronicMyelogenousK-5623.2
Leukemia_promyelocytic-HL-603.1
Leukemialymphoblastic(MOLT-4)2.85
Liver4.65
Lung3.95
Lymphnode3.05
Lymphoma_burkitts(Daudi)4.65
Lymphoma_burkitts(Raji)5
MedullaOblongata3.25
OccipitalLobe3.2
OlfactoryBulb2.8
Ovary2.35
Pancreas2.85
PancreaticIslet3.8
ParietalLobe3.7
Pituitary4.15
Placenta3.75
Pons3.45
PrefrontalCortex4.5
Prostate4.2
Salivarygland2.8
SkeletalMuscle4
Skin2.75
SmoothMuscle4.05
Spinalcord3.8
SubthalamicNucleus3.25
SuperiorCervicalGanglion4.05
TemporalLobe3.2
Testis3.1
TestisGermCell4.4
TestisIntersitial3.85
TestisLeydigCell5.8
TestisSeminiferousTubule3.2
Thalamus3.55
Thymus2.8
Thyroid4.5
Tongue3.45
Tonsil3.45
Trachea3
TrigeminalGanglion3.5
Uterus2.95
UterusCorpus3.15
WholeBlood3.95
Wholebrain3
colon3.65
pineal_day4.48
pineal_night4.36
retina4.325
small_intestine3.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P35427
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.01 ± 0.54
Basal Forebrain4.79 ± 0.34
Basal Part of Pons4.83 ± 0.53
Cerebellar Cortex4.6 ± 0.26
Cerebellar Nuclei4.7 ± 0.43
Claustrum4.84 ± 0.53
Epithalamus4.73 ± 0.36
Frontal Lobe4.95 ± 0.36
Globus Pallidus4.63 ± 0.3
Hypothalamus4.77 ± 0.31
Insula5.03 ± 0.2
Limbic Lobe4.87 ± 0.41
Mesencephalon4.83 ± 0.46
Myelencephalon4.84 ± 0.42
Occipital Lobe4.52 ± 0.43
Parietal Lobe4.91 ± 0.33
Pontine Tegmentum4.89 ± 0.35
Striatum4.73 ± 0.39
Subthalamus4.5 ± 0.49
Temporal Lobe5.01 ± 0.3
Thalamus4.84 ± 0.35
White Matter4.81 ± 0.08
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
BtrcCBCerebellum36.97
49.38
BtrcCTXCerebral cortex100
100
BtrcHIPHippocampal region98.95
100
BtrcHPFHippocampal formation100
100
BtrcHYHypothalamus83.99
60.63
BtrcLSXLateral septal complex95.63
63.69
BtrcMBMidbrain78.25
65.78
BtrcMYMedulla84.09
89.7
BtrcOLFOlfactory bulb100
100
BtrcPPons79.48
77.89
BtrcPALPallidum77.99
68.2
BtrcRHPRetrohippocampal region100
99.64
BtrcsAMYStriatum-like amygdalar nuclei98.83
81.24
BtrcSTRStriatum100
87.03
BtrcSTRdStriatum dorsal region100
87.07
BtrcSTRvStriatum ventral region100
90.13
BtrcTHThalamus66.87
50.89
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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