Annotation Detail for P4HA2
Basic Information Top
| Gene Symbol: | P4HA2 ( - ) |
|---|---|
| Gene Full Name: | prolyl 4-hydroxylase, alpha polypeptide II |
| Band: | 5q31.1 |
| Quick Links | Entrez ID:8974; OMIM: 600608; Uniprot ID:P4HA2_HUMAN; ENSEMBL ID: ENSG00000072682; HGNC ID: 8547 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.519568
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 12 / 70761 | 169 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 30 / 564012 | 53 | |
| neonate | 9 / 31097 | 289 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 7 / 55556 | 125 | |
| adult | 129 / 1939121 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 2 / 12794 | 156 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 |  |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 12 / 82823 | 144 | |
| colorectal tumor | 8 / 114246 | 70 | |
| esophageal tumor | 4 / 17290 | 231 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 10 / 263845 | 37 | |
| glioma | 11 / 106883 | 102 | |
| head and neck tumor | 5 / 136302 | 36 | |
| kidney tumor | 10 / 68959 | 145 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 6 / 96359 | 62 | |
| lung tumor | 8 / 103127 | 77 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 17 / 97250 | 174 | |
| normal | 247 / 3360307 | 73 | |
| ovarian tumor | 14 / 76682 | 182 | |
| pancreatic tumor | 7 / 104616 | 66 | |
| primitive neuroectodermal tumor of the CNS | 6 / 125680 | 47 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 |  |
| soft tissue/muscle tissue tumor | 6 / 125191 | 47 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 3 / 33197 | 90 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 1 / 29757 | 33 | |
| blood | 0 / 123478 | 0 | |
| bone | 10 / 71655 | 139 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 37 / 1100989 | 33 | |
| cervix | 6 / 48171 | 124 | |
| connective tissue | 29 / 149255 | 194 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 15 / 215722 | 69 | |
| esophagus | 4 / 20209 | 197 | |
| eye | 6 / 211054 | 28 | |
| heart | 16 / 89626 | 178 | |
| intestine | 24 / 234472 | 102 | |
| kidney | 27 / 211777 | 127 | |
| larynx | 0 / 24145 | 0 | |
| liver | 8 / 207743 | 38 | |
| lung | 26 / 336974 | 77 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 3 / 91610 | 32 | |
| mammary gland | 9 / 153271 | 58 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 18 / 107715 | 167 | |
| nerve | 3 / 15768 | 190 | |
| ovary | 19 / 102051 | 186 | |
| pancreas | 8 / 214812 | 37 | |
| parathyroid | 3 / 20539 | 146 | |
| pharynx | 2 / 41328 | 48 | |
| pituitary gland | 2 / 16585 | 120 | |
| placenta | 19 / 280825 | 67 | |
| prostate | 9 / 189345 | 47 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 21 / 210574 | 99 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 3 / 96619 | 31 | |
| testis | 17 / 330442 | 51 | |
| thymus | 6 / 81131 | 73 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 4 / 52413 | 76 | |
| umbilical cord | 7 / 13680 | 511 | |
| uterus | 19 / 232878 | 81 | |
| vascular | 20 / 51780 | 386 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 202733_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 4.8 | |
| Adipocyte | 70.95 | |
| AdrenalCortex | 4.35 | |
| Adrenalgland | 4 | |
| Amygdala | 4.65 | |
| Appendix | 4.25 | |
| AtrioventricularNode | 3.15 | |
| BDCA4+_DentriticCells | 4.6 | |
| Bonemarrow | 4.05 | |
| BronchialEpithelialCells | 221.65 | |
| CD105+_Endothelial | 4.3 | |
| CD14+_Monocytes | 4.45 | |
| CD19+_BCells(neg._sel.) | 4.15 | |
| CD33+_Myeloid | 5.4 | |
| CD34+ | 5.4 | |
| CD4+_Tcells | 4.5 | |
| CD56+_NKCells | 4.9 | |
| CD71+_EarlyErythroid | 3.9 | |
| CD8+_Tcells | 3.85 | |
| CardiacMyocytes | 374.1 | |
| Caudatenucleus | 3.7 | |
| Cerebellum | 3.35 | |
| CerebellumPeduncles | 4.7 | |
| CiliaryGanglion | 3.35 | |
| CingulateCortex | 4.2 | |
| Colorectaladenocarcinoma | 90.75 | |
| DorsalRootGanglion | 5.15 | |
| FetalThyroid | 7.15 | |
| Fetalbrain | 4.15 | |
| Fetalliver | 3.45 | |
| Fetallung | 32.8 | |
| GlobusPallidus | 3.05 | |
| Heart | 28.55 | |
| Hypothalamus | 4.85 | |
| Kidney | 58.05 | |
| Leukemia_chronicMyelogenousK-562 | 30.1 | |
| Leukemia_promyelocytic-HL-60 | 3.7 | |
| Leukemialymphoblastic(MOLT-4) | 3.35 | |
| Liver | 5.5 | |
| Lung | 123.45 | |
| Lymphnode | 3.6 | |
| Lymphoma_burkitts(Daudi) | 5.25 | |
| Lymphoma_burkitts(Raji) | 5.8 | |
| MedullaOblongata | 3.85 | |
| OccipitalLobe | 3.7 | |
| OlfactoryBulb | 8.1 | |
| Ovary | 2.75 | |
| Pancreas | 71.95 | |
| PancreaticIslet | 98.95 | |
| ParietalLobe | 4.4 | |
| Pituitary | 55.7 | |
| Placenta | 61.7 | |
| Pons | 3.95 | |
| PrefrontalCortex | 6.8 | |
| Prostate | 8.45 | |
| Salivarygland | 7.6 | |
| SkeletalMuscle | 4.75 | |
| Skin | 6 | |
| SmoothMuscle | 719.95 | |
| Spinalcord | 4.45 | |
| SubthalamicNucleus | 3.8 | |
| SuperiorCervicalGanglion | 4.7 | |
| TemporalLobe | 3.8 | |
| Testis | 4.65 | |
| TestisGermCell | 7.05 | |
| TestisIntersitial | 3.5 | |
| TestisLeydigCell | 6.6 | |
| TestisSeminiferousTubule | 3.65 | |
| Thalamus | 4.25 | |
| Thymus | 3.5 | |
| Thyroid | 5.4 | |
| Tongue | 4.7 | |
| Tonsil | 4.05 | |
| Trachea | 5.5 | |
| TrigeminalGanglion | 4.35 | |
| Uterus | 50.8 | |
| UterusCorpus | 5.7 | |
| WholeBlood | 4.5 | |
| Wholebrain | 3.6 | |
| colon | 79.45 | |
| pineal_day | 462.28 | |
| pineal_night | 486.98 | |
| retina | 25.85 | |
| small_intestine | 48.15 | |
- Probe name: A_23_P18966
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.53 ± 0.48 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.68 ± 0.52 | |
| Basal Part of Pons | 4.43 ± 0.52 | |
| Cerebellar Cortex | 4.86 ± 0.48 | |
| Cerebellar Nuclei | 4.83 ± 0.76 | |
| Claustrum | 5.97 ± 0.59 | |
| Epithalamus | 4.96 ± 0.19 | |
| Frontal Lobe | 5.2 ± 0.44 | |
| Globus Pallidus | 4.84 ± 1.18 | |
| Hypothalamus | 5.56 ± 0.54 | |
| Insula | 5.41 ± 0.36 | |
| Limbic Lobe | 5.59 ± 0.43 | |
| Mesencephalon | 5.09 ± 0.63 | |
| Myelencephalon | 5.12 ± 0.7 | |
| Occipital Lobe | 5.2 ± 0.53 | |
| Parietal Lobe | 5.21 ± 0.63 | |
| Pontine Tegmentum | 5.41 ± 0.55 | |
| Striatum | 4.32 ± 0.79 | |
| Subthalamus | 5.04 ± 0.6 | |
| Temporal Lobe | 5.32 ± 0.48 | |
| Thalamus | 4.96 ± 0.49 | |
| White Matter | 4.12 ± 0.82 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| P4ha2 | CB | Cerebellum | 19.49 | |
| 30.21 | | |||
| P4ha2 | CTX | Cerebral cortex | 15.9 | |
| 11.7 | | |||
| P4ha2 | HIP | Hippocampal region | 21.2 | |
| 24.15 | | |||
| P4ha2 | HPF | Hippocampal formation | 23.75 | |
| 22.79 | | |||
| P4ha2 | HY | Hypothalamus | 15.4 | |
| 11.93 | | |||
| P4ha2 | LSX | Lateral septal complex | 4.46 | |
| 3.5 | | |||
| P4ha2 | MB | Midbrain | 14.76 | |
| 14.54 | | |||
| P4ha2 | MY | Medulla | 19.91 | |
| 23.52 | | |||
| P4ha2 | OLF | Olfactory bulb | 26.38 | |
| 20.06 | | |||
| P4ha2 | P | Pons | 18 | |
| 19.8 | | |||
| P4ha2 | PAL | Pallidum | 9.32 | |
| 8.36 | | |||
| P4ha2 | RHP | Retrohippocampal region | 30.17 | |
| 23.48 | | |||
| P4ha2 | sAMY | Striatum-like amygdalar nuclei | 9.69 | |
| 7.24 | | |||
| P4ha2 | STR | Striatum | 4.55 | |
| 3.49 | | |||
| P4ha2 | STRd | Striatum dorsal region | 2.8 | |
| 2.18 | | |||
| P4ha2 | STRv | Striatum ventral region | 6.96 | |
| 5.19 | | |||
| P4ha2 | TH | Thalamus | 24.95 | |
| 21.63 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| P4HA2_HUMAN_341 | 12 | 341 | 352 | YYDVMSDEEIER | PRIDE |
| PAp00003065 | 14 | 522 | 535 | GQEFLRPCGSTEVD | Peptide Atlas |