AutismKB 2.0

Annotation Detail for NAV1


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Basic Information Top
Gene Symbol:NAV1 ( DKFZp781D0314,FLJ12560,FLJ14203,KIAA1151,MGC14961,POMFIL3,STEERIN1,UNC53H1 )
Gene Full Name: neuron navigator 1
Band: 1q32.1
Quick LinksEntrez ID:89796; OMIM: 611628; Uniprot ID:NAV1_HUMAN; ENSEMBL ID: ENSG00000134369; HGNC ID: 15989
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst6 / 6231996
fetus91 / 564012161
neonate2 / 3109764
infant1 / 2362042
juvenile0 / 555560 
adult176 / 193912190
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma2 / 17475114
breast (mammary gland) tumor13 / 94178138
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor41 / 263845155
glioma15 / 106883140
head and neck tumor29 / 136302212
kidney tumor4 / 6895958
leukemia5 / 9584252
liver tumor4 / 9635941
lung tumor7 / 10312767
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal254 / 336030775
ovarian tumor4 / 7668252
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor10 / 12494980
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland3 / 3319790
ascites0 / 400150 
bladder3 / 29757100
blood3 / 12347824
bone5 / 7165569
bone marrow2 / 4880140
brain143 / 1100989129
cervix0 / 481710 
connective tissue6 / 14925540
ear1 / 1621261
embryonic tissue24 / 215722111
esophagus1 / 2020949
eye21 / 21105499
heart16 / 89626178
intestine5 / 23447221
kidney10 / 21177747
larynx1 / 2414541
liver6 / 20774328
lung26 / 33697477
lymph1 / 4427022
lymph node0 / 916100 
mammary gland14 / 15327191
mouth24 / 67052357
muscle3 / 10771527
nerve0 / 157680 
ovary4 / 10205139
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta20 / 28082571
prostate7 / 18934536
salivary gland0 / 201550 
skin20 / 21057494
spleen0 / 539520 
stomach2 / 9661920
testis18 / 33044254
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord4 / 13680292
uterus14 / 23287860
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P212096
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.44 ± 0.29
Basal Forebrain8.46 ± 0.12
Basal Part of Pons8.09 ± 0.26
Cerebellar Cortex8.04 ± 0.2
Cerebellar Nuclei8.15 ± 0.24
Claustrum8.42 ± 0.37
Epithalamus7.79 ± 0.6
Frontal Lobe8.38 ± 0.38
Globus Pallidus8.98 ± 0.12
Hypothalamus8.1 ± 0.39
Insula8.39 ± 0.28
Limbic Lobe8.67 ± 0.31
Mesencephalon8.41 ± 0.34
Myelencephalon8.41 ± 0.39
Occipital Lobe8.4 ± 0.29
Parietal Lobe8.33 ± 0.37
Pontine Tegmentum8.4 ± 0.36
Striatum8.41 ± 0.38
Subthalamus8.02 ± 0.15
Temporal Lobe8.49 ± 0.31
Thalamus8.53 ± 0.26
White Matter9.76 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nav1CBCerebellum20.52
22.3
Nav1CTXCerebral cortex35.54
28.24
Nav1HIPHippocampal region32.09
41.38
Nav1HPFHippocampal formation29.94
32.15
Nav1HYHypothalamus16.29
11.35
Nav1LSXLateral septal complex10.42
7.24
Nav1MBMidbrain18.14
15.32
Nav1MYMedulla29.57
25.93
Nav1OLFOlfactory bulb67.82
63.23
Nav1PPons26.03
22.26
Nav1PALPallidum22.15
16.73
Nav1RHPRetrohippocampal region26.43
20.16
Nav1sAMYStriatum-like amygdalar nuclei18.29
12.42
Nav1STRStriatum9.92
7.48
Nav1STRdStriatum dorsal region7.92
6.42
Nav1STRvStriatum ventral region11.76
8.24
Nav1THThalamus21.05
16.23
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00072657 14 932 945 LEALNSAHQLDQLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018