AutismKB 2.0

Annotation Detail for CCNE1


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Basic Information Top
Gene Symbol:CCNE1 ( CCNE )
Gene Full Name: cyclin E1
Band: 19q12
Quick LinksEntrez ID:898; OMIM: 123837; Uniprot ID:CCNE1_HUMAN; ENSEMBL ID: ENSG00000105173; HGNC ID: 1589
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor12 / 26384545
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor8 / 9635983
lung tumor1 / 1031279
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal31 / 33603079
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma3 / 4635664
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye4 / 21105418
heart4 / 8962644
intestine8 / 23447234
kidney2 / 2117779
larynx0 / 241450 
liver8 / 20774338
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta32 / 280825113
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213523_at
Cell line Expression level Expression bar
721_B_lymphoblasts28.35
Adipocyte6.35
AdrenalCortex7.45
Adrenalgland5.95
Amygdala6.95
Appendix6.9
AtrioventricularNode4.95
BDCA4+_DentriticCells7.15
Bonemarrow22.5
BronchialEpithelialCells7.6
CD105+_Endothelial1376.15
CD14+_Monocytes6.9
CD19+_BCells(neg._sel.)7.7
CD33+_Myeloid8.15
CD34+97.3
CD4+_Tcells6.75
CD56+_NKCells6.85
CD71+_EarlyErythroid388.7
CD8+_Tcells6.05
CardiacMyocytes10.2
Caudatenucleus5.8
Cerebellum8.55
CerebellumPeduncles7.7
CiliaryGanglion4.75
CingulateCortex7
Colorectaladenocarcinoma6.8
DorsalRootGanglion5.05
FetalThyroid6.6
Fetalbrain6.55
Fetalliver15.2
Fetallung5.05
GlobusPallidus4.85
Heart17.3
Hypothalamus7.25
Kidney5.65
Leukemia_chronicMyelogenousK-56216.05
Leukemia_promyelocytic-HL-6015.05
Leukemialymphoblastic(MOLT-4)21.05
Liver9.8
Lung6.9
Lymphnode6.25
Lymphoma_burkitts(Daudi)8.7
Lymphoma_burkitts(Raji)10.5
MedullaOblongata5.95
OccipitalLobe5.8
OlfactoryBulb4.95
Ovary4.3
Pancreas5.15
PancreaticIslet6.85
ParietalLobe7.05
Pituitary7.8
Placenta50.75
Pons6.35
PrefrontalCortex8.15
Prostate7.5
Salivarygland5.85
SkeletalMuscle10.5
Skin4.9
SmoothMuscle8.15
Spinalcord7.2
SubthalamicNucleus5.9
SuperiorCervicalGanglion7.8
TemporalLobe6.1
Testis29.65
TestisGermCell7.2
TestisIntersitial9.7
TestisLeydigCell7.35
TestisSeminiferousTubule9.7
Thalamus6.9
Thymus5.25
Thyroid8.15
Tongue6.8
Tonsil6.45
Trachea5.6
TrigeminalGanglion6.65
Uterus5.25
UterusCorpus5.9
WholeBlood6.85
Wholebrain9.2
colon6.95
pineal_day7.9
pineal_night7.94
retina7.95
small_intestine7.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14613_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.38 ± 0.69
Basal Forebrain2.78 ± 0.37
Basal Part of Pons3.34 ± 0.47
Cerebellar Cortex3.57 ± 0.4
Cerebellar Nuclei3.07 ± 0.56
Claustrum3.33 ± 0.54
Epithalamus2.86 ± 0.77
Frontal Lobe3.24 ± 0.6
Globus Pallidus2.45 ± 0.64
Hypothalamus2.99 ± 0.54
Insula3.3 ± 0.55
Limbic Lobe3.05 ± 0.63
Mesencephalon3.11 ± 0.68
Myelencephalon3.13 ± 0.58
Occipital Lobe3.04 ± 0.65
Parietal Lobe3.2 ± 0.51
Pontine Tegmentum3.21 ± 0.58
Striatum2.98 ± 0.59
Subthalamus3.4 ± 0.29
Temporal Lobe3.15 ± 0.56
Thalamus3.16 ± 0.58
White Matter1.5 ± 0.57
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ccne1CBCerebellum1.51
1.94
Ccne1CTXCerebral cortex5.71
4.03
Ccne1HIPHippocampal region3.58
3.41
Ccne1HPFHippocampal formation2.97
2.75
Ccne1HYHypothalamus0.83
0.87
Ccne1LSXLateral septal complex0.2
0.19
Ccne1MBMidbrain1.38
1.5
Ccne1MYMedulla2.25
2.4
Ccne1OLFOlfactory bulb10.62
8.29
Ccne1PPons3.05
3.15
Ccne1PALPallidum2.18
1.95
Ccne1RHPRetrohippocampal region1.9
1.82
Ccne1sAMYStriatum-like amygdalar nuclei1.42
0.99
Ccne1STRStriatum1.01
0.76
Ccne1STRdStriatum dorsal region0.96
0.67
Ccne1STRvStriatum ventral region1.29
1.09
Ccne1THThalamus2.62
2.04
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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