AutismKB 2.0

Annotation Detail for CHRFAM7A


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Basic Information Top
Gene Symbol:CHRFAM7A ( CHRNA7,CHRNA7-DR1,D-10,MGC120482,MGC120483 )
Gene Full Name: CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
Band: 15q13.2
Quick LinksEntrez ID:89832; OMIM: 609756; Uniprot ID:CRFM7_HUMAN; ENSEMBL ID: ENSG00000166664; HGNC ID: 15781
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult12 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal19 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain7 / 11009896
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine5 / 23447221
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus1 / 8113112
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210123_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.2
Adipocyte6.1
AdrenalCortex6.85
Adrenalgland5.15
Amygdala6.6
Appendix6.1
AtrioventricularNode4.55
BDCA4+_DentriticCells7.5
Bonemarrow6
BronchialEpithelialCells6.15
CD105+_Endothelial6.25
CD14+_Monocytes6.65
CD19+_BCells(neg._sel.)7.65
CD33+_Myeloid8
CD34+9.6
CD4+_Tcells6.85
CD56+_NKCells7.5
CD71+_EarlyErythroid5.75
CD8+_Tcells5.85
CardiacMyocytes7.65
Caudatenucleus5.55
Cerebellum5
CerebellumPeduncles6.95
CiliaryGanglion4.25
CingulateCortex6.35
Colorectaladenocarcinoma6.1
DorsalRootGanglion4.6
FetalThyroid6
Fetalbrain6.2
Fetalliver5.25
Fetallung5.2
GlobusPallidus4.75
Heart7.7
Hypothalamus6.7
Kidney4.9
Leukemia_chronicMyelogenousK-5625.6
Leukemia_promyelocytic-HL-605.4
Leukemialymphoblastic(MOLT-4)5
Liver8
Lung6.85
Lymphnode5.4
Lymphoma_burkitts(Daudi)7.8
Lymphoma_burkitts(Raji)8.5
MedullaOblongata5.7
OccipitalLobe5.55
OlfactoryBulb4.8
Ovary4.05
Pancreas4.9
PancreaticIslet6.6
ParietalLobe6.4
Pituitary7.2
Placenta6.45
Pons5.9
PrefrontalCortex7.85
Prostate8.9
Salivarygland4.9
SkeletalMuscle7.4
Skin4.65
SmoothMuscle7.05
Spinalcord6.6
SubthalamicNucleus6.4
SuperiorCervicalGanglion6.8
TemporalLobe5.6
Testis7.05
TestisGermCell5.75
TestisIntersitial5.3
TestisLeydigCell6.05
TestisSeminiferousTubule5.35
Thalamus6.3
Thymus4.9
Thyroid7.85
Tongue6
Tonsil6
Trachea5.15
TrigeminalGanglion6
Uterus5.1
UterusCorpus5.5
WholeBlood6.5
Wholebrain6.55
colon6.2
pineal_day7.48
pineal_night7.82
retina7.575
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15459_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.18 ± 1.35
Basal Forebrain1.58 ± 0.2
Basal Part of Pons1.24 ± 0.37
Cerebellar Cortex1.37 ± 0.66
Cerebellar Nuclei1.81 ± 0.68
Claustrum2.48 ± 0.87
Epithalamus1.33 ± 0.75
Frontal Lobe1.41 ± 0.56
Globus Pallidus2.09 ± 0.3
Hypothalamus1.67 ± 0.73
Insula1.6 ± 0.46
Limbic Lobe1.56 ± 0.59
Mesencephalon1.74 ± 0.66
Myelencephalon1.64 ± 0.64
Occipital Lobe1.59 ± 0.57
Parietal Lobe1.59 ± 0.69
Pontine Tegmentum1.61 ± 0.67
Striatum1.78 ± 0.5
Subthalamus1.73 ± 0.62
Temporal Lobe1.52 ± 0.69
Thalamus1.55 ± 0.56
White Matter1.89 ± 0.26
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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