AutismKB 2.0

Annotation Detail for ABCC10


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Basic Information Top
Gene Symbol:ABCC10 ( EST182763,MRP7,SIMRP7 )
Gene Full Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 10
Band: 6p21.1
Quick LinksEntrez ID:89845; OMIM: 612509; Uniprot ID:MRP7_HUMAN; ENSEMBL ID: ENSG00000124574; HGNC ID: 52
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult38 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor7 / 10312767
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal46 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain13 / 110098911
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine3 / 23447212
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung10 / 33697429
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary9 / 10205188
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta1 / 2808253
prostate7 / 18934536
salivary gland0 / 201550 
skin6 / 21057428
spleen1 / 5395218
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil5 / 16999294
trachea0 / 524130 
umbilical cord0 / 136800 
uterus12 / 23287851
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215873_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.85
Adipocyte5.35
AdrenalCortex6.25
Adrenalgland5.5
Amygdala6.45
Appendix6.6
AtrioventricularNode5.35
BDCA4+_DentriticCells6.7
Bonemarrow6.5
BronchialEpithelialCells5.7
CD105+_Endothelial5.95
CD14+_Monocytes10.25
CD19+_BCells(neg._sel.)6.5
CD33+_Myeloid8.5
CD34+8.2
CD4+_Tcells36.45
CD56+_NKCells27.05
CD71+_EarlyErythroid4.95
CD8+_Tcells27.4
CardiacMyocytes8.85
Caudatenucleus5.8
Cerebellum6.65
CerebellumPeduncles7.55
CiliaryGanglion4.65
CingulateCortex6.95
Colorectaladenocarcinoma9.55
DorsalRootGanglion5.1
FetalThyroid9.5
Fetalbrain9.2
Fetalliver5.45
Fetallung5.15
GlobusPallidus5.3
Heart9.2
Hypothalamus6.85
Kidney5.4
Leukemia_chronicMyelogenousK-5629.05
Leukemia_promyelocytic-HL-604.75
Leukemialymphoblastic(MOLT-4)7
Liver8.75
Lung7.8
Lymphnode8.1
Lymphoma_burkitts(Daudi)6.95
Lymphoma_burkitts(Raji)9.95
MedullaOblongata5.8
OccipitalLobe5.95
OlfactoryBulb4.5
Ovary5.7
Pancreas4.9
PancreaticIslet6.4
ParietalLobe6.95
Pituitary8.15
Placenta6.5
Pons5.8
PrefrontalCortex8.6
Prostate13.45
Salivarygland5.05
SkeletalMuscle8.2
Skin4.65
SmoothMuscle7.75
Spinalcord6.15
SubthalamicNucleus5.3
SuperiorCervicalGanglion14.2
TemporalLobe5.3
Testis5.5
TestisGermCell6.5
TestisIntersitial6.6
TestisLeydigCell6.35
TestisSeminiferousTubule7.8
Thalamus6.6
Thymus7.3
Thyroid13
Tongue5.9
Tonsil5.65
Trachea5.25
TrigeminalGanglion9.1
Uterus8.35
UterusCorpus5.1
WholeBlood7.1
Wholebrain6.2
colon6.45
pineal_day10.7
pineal_night10.84
retina7.775
small_intestine6.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16148_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.49 ± 0.95
Basal Forebrain1.59 ± 0.21
Basal Part of Pons1.71 ± 0.32
Cerebellar Cortex2.35 ± 0.61
Cerebellar Nuclei2.22 ± 0.66
Claustrum2.5 ± 0.61
Epithalamus1.92 ± 0.71
Frontal Lobe2.04 ± 0.71
Globus Pallidus1.86 ± 0.68
Hypothalamus2.12 ± 0.82
Insula2.1 ± 0.64
Limbic Lobe2.02 ± 0.61
Mesencephalon2.13 ± 0.7
Myelencephalon2.07 ± 0.65
Occipital Lobe2.01 ± 0.74
Parietal Lobe2.01 ± 0.7
Pontine Tegmentum2.15 ± 0.76
Striatum1.62 ± 0.67
Subthalamus2.03 ± 0.71
Temporal Lobe2.13 ± 0.66
Thalamus2.11 ± 0.62
White Matter2.16 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Abcc10CBCerebellum20.05
23.27
Abcc10CTXCerebral cortex18.45
13.02
Abcc10HIPHippocampal region12.02
11.02
Abcc10HPFHippocampal formation11.44
9.74
Abcc10HYHypothalamus8.54
6.02
Abcc10LSXLateral septal complex4.35
2.63
Abcc10MBMidbrain14.1
11.58
Abcc10MYMedulla28.94
29.18
Abcc10OLFOlfactory bulb26.86
20.03
Abcc10PPons18.98
17.25
Abcc10PALPallidum13.04
9.71
Abcc10RHPRetrohippocampal region11.04
8.35
Abcc10sAMYStriatum-like amygdalar nuclei3.51
2.08
Abcc10STRStriatum8.5
5.87
Abcc10STRdStriatum dorsal region5.6
4.01
Abcc10STRvStriatum ventral region20.64
13.25
Abcc10THThalamus13.56
9.67
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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