Annotation Detail for FGD3
Basic Information Top
| Gene Symbol: | FGD3 ( FLJ00004,MGC117260,ZFYVE5 ) |
|---|---|
| Gene Full Name: | FYVE, RhoGEF and PH domain containing 3 |
| Band: | 9q22.31 |
| Quick Links | Entrez ID:89846; OMIM: NA; Uniprot ID:FGD3_HUMAN; ENSEMBL ID: ENSG00000127084; HGNC ID: 16027 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.411081
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 15 / 564012 | 26 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 66 / 1939121 | 34 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 |  |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 |  |
| germ cell tumor | 3 / 263845 | 11 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 23 / 95842 | 239 |  |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 9 / 71755 | 125 | |
| non-neoplasia | 7 / 97250 | 71 | |
| normal | 115 / 3360307 | 34 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 48 / 123478 | 388 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 4 / 48801 | 81 | |
| brain | 17 / 1100989 | 15 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 10 / 149255 | 66 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 5 / 211054 | 23 | |
| heart | 1 / 89626 | 11 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 9 / 336974 | 26 | |
| lymph | 7 / 44270 | 158 | |
| lymph node | 5 / 91610 | 54 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 14 / 280825 | 49 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 16 / 53952 | 296 | |
| stomach | 1 / 96619 | 10 | |
| testis | 5 / 330442 | 15 | |
| thymus | 56 / 81131 | 690 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 5 / 16999 | 294 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_23_P134980
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.61 ± 0.81 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.99 ± 0.6 | |
| Basal Part of Pons | 3.03 ± 0.73 | |
| Cerebellar Cortex | 2.47 ± 0.65 | |
| Cerebellar Nuclei | 3.41 ± 0.89 | |
| Claustrum | 3.49 ± 1.19 | |
| Epithalamus | 3.71 ± 0.74 | |
| Frontal Lobe | 2.87 ± 0.81 | |
| Globus Pallidus | 4.43 ± 0.51 | |
| Hypothalamus | 3.03 ± 0.84 | |
| Insula | 2.59 ± 0.76 | |
| Limbic Lobe | 3 ± 0.89 | |
| Mesencephalon | 3.06 ± 0.92 | |
| Myelencephalon | 3.09 ± 0.76 | |
| Occipital Lobe | 2.7 ± 0.92 | |
| Parietal Lobe | 3.15 ± 0.94 | |
| Pontine Tegmentum | 3.09 ± 1.03 | |
| Striatum | 3.4 ± 1.12 | |
| Subthalamus | 2.77 ± 0.5 | |
| Temporal Lobe | 3.03 ± 0.82 | |
| Thalamus | 2.9 ± 0.63 | |
| White Matter | 3.68 ± 0.53 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Fgd3 | CB | Cerebellum | 21.29 | |
| 53.86 | | |||
| Fgd3 | CTX | Cerebral cortex | 10.79 | |
| 8 | | |||
| Fgd3 | HIP | Hippocampal region | 7.57 | |
| 7.26 | | |||
| Fgd3 | HPF | Hippocampal formation | 8.68 | |
| 7.55 | | |||
| Fgd3 | HY | Hypothalamus | 2.96 | |
| 2.21 | | |||
| Fgd3 | LSX | Lateral septal complex | 0.97 | |
| 0.85 | | |||
| Fgd3 | MB | Midbrain | 4.15 | |
| 3.75 | | |||
| Fgd3 | MY | Medulla | 12.44 | |
| 16.38 | | |||
| Fgd3 | OLF | Olfactory bulb | 17.67 | |
| 13.34 | | |||
| Fgd3 | P | Pons | 10.05 | |
| 10.75 | | |||
| Fgd3 | PAL | Pallidum | 2.13 | |
| 1.76 | | |||
| Fgd3 | RHP | Retrohippocampal region | 10.4 | |
| 7.86 | | |||
| Fgd3 | sAMY | Striatum-like amygdalar nuclei | 1.49 | |
| 1.07 | | |||
| Fgd3 | STR | Striatum | 3.38 | |
| 2.52 | | |||
| Fgd3 | STRd | Striatum dorsal region | 4.07 | |
| 3.07 | | |||
| Fgd3 | STRv | Striatum ventral region | 3.46 | |
| 2.35 | | |||
| Fgd3 | TH | Thalamus | 20.61 | |
| 16.17 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| FGD3_HUMAN_408 | 9 | 408 | 416 | LMGQKFSVR | PRIDE |
| PAp00039381 | 30 | 41 | 70 | AHCGDPVSLAAAGDGSPDIGPTGELSGSLK | Peptide Atlas |