AutismKB 2.0

Annotation Detail for SEC16B


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Basic Information Top
Gene Symbol:SEC16B ( DKFZp686C2486,FLJ23871,FLJ25761,FLJ33652,FLJ36620,LZTR2,PGPR-p117,RGPR,SEC16S )
Gene Full Name: SEC16 homolog B (S. cerevisiae)
Band: 1q25.2
Quick LinksEntrez ID:89866; OMIM: 612855; Uniprot ID:SC16B_HUMAN; ENSEMBL ID: ENSG00000120341; HGNC ID: 30301
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal25 / 33603077
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain5 / 11009894
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine9 / 23447238
kidney2 / 2117779
larynx0 / 241450 
liver3 / 20774314
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen2 / 5395237
stomach2 / 9661920
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12206_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.21 ± 0.99
Basal Forebrain1.72 ± 0.2
Basal Part of Pons1.4 ± 0.32
Cerebellar Cortex1.63 ± 0.68
Cerebellar Nuclei2.11 ± 0.71
Claustrum2.6 ± 0.85
Epithalamus1.5 ± 0.74
Frontal Lobe1.61 ± 0.61
Globus Pallidus2.35 ± 0.24
Hypothalamus1.8 ± 0.69
Insula1.72 ± 0.56
Limbic Lobe1.8 ± 0.59
Mesencephalon1.96 ± 0.65
Myelencephalon1.81 ± 0.65
Occipital Lobe1.86 ± 0.64
Parietal Lobe1.85 ± 0.71
Pontine Tegmentum1.86 ± 0.68
Striatum1.92 ± 0.5
Subthalamus2.11 ± 0.87
Temporal Lobe1.73 ± 0.66
Thalamus1.75 ± 0.56
White Matter2.24 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lztr2CBCerebellum5.75
7.01
Lztr2CTXCerebral cortex3.57
2.68
Lztr2HIPHippocampal region4.38
4.7
Lztr2HPFHippocampal formation3.14
3.26
Lztr2HYHypothalamus1.96
1.56
Lztr2LSXLateral septal complex1.56
2.03
Lztr2MBMidbrain1.1
1.47
Lztr2MYMedulla6.27
6.34
Lztr2OLFOlfactory bulb6.8
4.78
Lztr2PPons4.43
4.98
Lztr2PALPallidum1.46
1.43
Lztr2RHPRetrohippocampal region0.94
1.15
Lztr2sAMYStriatum-like amygdalar nuclei1.75
2.28
Lztr2STRStriatum1.24
1.35
Lztr2STRdStriatum dorsal region0.76
0.97
Lztr2STRvStriatum ventral region2.57
1.78
Lztr2THThalamus2.82
2.46
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018