AutismKB 2.0

Annotation Detail for C3orf15


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Basic Information Top
Gene Symbol:C3orf15 ( AAT1,AAT1alpha,DKFZp781A2221 )
Gene Full Name: chromosome 3 open reading frame 15
Band: 3q12-q13.3
Quick LinksEntrez ID:89876; OMIM: 609910; Uniprot ID:AAT1_HUMAN; ENSEMBL ID: ENSG00000183833; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult14 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal44 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung11 / 33697432
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle3 / 10771527
nerve1 / 1576863
ovary3 / 10205129
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis30 / 33044290
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P230649
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.77 ± 0.8
Basal Forebrain3.4 ± 0.45
Basal Part of Pons3.25 ± 0.53
Cerebellar Cortex3.44 ± 0.62
Cerebellar Nuclei3.47 ± 0.71
Claustrum3.83 ± 0.58
Epithalamus5.2 ± 0.94
Frontal Lobe3.46 ± 0.7
Globus Pallidus2.96 ± 0.61
Hypothalamus3.51 ± 0.61
Insula3.61 ± 0.41
Limbic Lobe3.57 ± 0.6
Mesencephalon3.76 ± 0.64
Myelencephalon3.58 ± 0.72
Occipital Lobe3.72 ± 0.93
Parietal Lobe3.49 ± 0.63
Pontine Tegmentum3.55 ± 0.69
Striatum3.89 ± 0.9
Subthalamus3.42 ± 0.62
Temporal Lobe3.62 ± 0.7
Thalamus3.38 ± 0.57
White Matter2.85 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
4932425I24RikCBCerebellum25.3
38.96
4932425I24RikCTXCerebral cortex44.34
38.64
4932425I24RikHIPHippocampal region27.62
36.75
4932425I24RikHPFHippocampal formation28.23
31.59
4932425I24RikHYHypothalamus5.94
5.65
4932425I24RikLSXLateral septal complex14.28
14.14
4932425I24RikMBMidbrain10.28
11.41
4932425I24RikMYMedulla21.45
29.74
4932425I24RikOLFOlfactory bulb32.06
32.54
4932425I24RikPPons14.73
21.84
4932425I24RikPALPallidum12.6
14.29
4932425I24RikRHPRetrohippocampal region29.68
25.68
4932425I24RiksAMYStriatum-like amygdalar nuclei24.34
19.02
4932425I24RikSTRStriatum24.27
21.35
4932425I24RikSTRdStriatum dorsal region26.18
22.18
4932425I24RikSTRvStriatum ventral region21.21
22.51
4932425I24RikTHThalamus10.06
12.09
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018