AutismKB 2.0

Annotation Detail for PAPLN


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Basic Information Top
Gene Symbol:PAPLN ( DKFZp434F053,MGC50452 )
Gene Full Name: papilin, proteoglycan-like sulfated glycoprotein
Band: 14q24.2
Quick LinksEntrez ID:89932; OMIM: NA; Uniprot ID:PPN_HUMAN; ENSEMBL ID: ENSG00000100767; HGNC ID: 19262
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor11 / 26384541
glioma3 / 10688328
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal58 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain17 / 110098915
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye8 / 21105437
heart0 / 896260 
intestine3 / 23447212
kidney19 / 21177789
larynx1 / 2414541
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth3 / 6705244
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach1 / 9661910
testis6 / 33044218
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P184732
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.77 ± 0.6
Basal Forebrain5.38 ± 0.14
Basal Part of Pons5.46 ± 0.43
Cerebellar Cortex5.11 ± 0.43
Cerebellar Nuclei5.45 ± 0.45
Claustrum5.97 ± 0.47
Epithalamus4.91 ± 0.43
Frontal Lobe5.25 ± 0.52
Globus Pallidus5.81 ± 0.28
Hypothalamus5.08 ± 0.27
Insula5.24 ± 0.23
Limbic Lobe5.45 ± 0.48
Mesencephalon5.4 ± 0.55
Myelencephalon5.41 ± 0.49
Occipital Lobe5.41 ± 0.55
Parietal Lobe5.34 ± 0.49
Pontine Tegmentum5.23 ± 0.44
Striatum5.46 ± 0.42
Subthalamus5.27 ± 0.16
Temporal Lobe5.3 ± 0.44
Thalamus5.35 ± 0.44
White Matter5.82 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PaplnCBCerebellum6.5
9.6
PaplnCTXCerebral cortex0.65
0.88
PaplnHIPHippocampal region0.26
0.31
PaplnHPFHippocampal formation0.29
0.4
PaplnHYHypothalamus0.26
0.25
PaplnLSXLateral septal complex0.41
0.56
PaplnMBMidbrain0.87
1.03
PaplnMYMedulla3.94
4.13
PaplnOLFOlfactory bulb1.52
1.43
PaplnPPons0.92
1.2
PaplnPALPallidum0.2
0.26
PaplnRHPRetrohippocampal region0.3
0.5
PaplnsAMYStriatum-like amygdalar nuclei0.49
0.34
PaplnSTRStriatum0.27
0.3
PaplnSTRdStriatum dorsal region0.25
0.29
PaplnSTRvStriatum ventral region0.22
0.28
PaplnTHThalamus0.5
0.4
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018