AutismKB 2.0

Annotation Detail for RHOT2


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Basic Information Top
Gene Symbol:RHOT2 ( ARHT2,C16orf39,MIRO-2,RASL )
Gene Full Name: ras homolog gene family, member T2
Band: 16p13.3
Quick LinksEntrez ID:89941; OMIM: NA; Uniprot ID:MIRO2_HUMAN; ENSEMBL ID: ENSG00000140983; HGNC ID: 21169
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst13 / 62319208
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult157 / 193912180
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor14 / 114246122
esophageal tumor1 / 1729057
gastrointestinal tumor12 / 119369100
germ cell tumor7 / 26384526
glioma11 / 106883102
head and neck tumor6 / 13630244
kidney tumor8 / 68959116
leukemia11 / 95842114
liver tumor5 / 9635951
lung tumor14 / 103127135
lymphoma12 / 71755167
non-neoplasia1 / 9725010
normal195 / 336030758
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS21 / 125680167
prostate cancer10 / 10268097
retinoblastoma2 / 4635643
skin tumor11 / 12494988
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood20 / 123478161
bone10 / 71655139
bone marrow1 / 4880120
brain65 / 110098959
cervix0 / 481710 
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue25 / 215722115
esophagus1 / 2020949
eye17 / 21105480
heart0 / 896260 
intestine24 / 234472102
kidney11 / 21177751
larynx2 / 2414582
liver7 / 20774333
lung33 / 33697497
lymph4 / 4427090
lymph node11 / 91610120
mammary gland6 / 15327139
mouth3 / 6705244
muscle0 / 1077150 
nerve1 / 1576863
ovary10 / 10205197
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta19 / 28082567
prostate11 / 18934558
salivary gland0 / 201550 
skin15 / 21057471
spleen2 / 5395237
stomach3 / 9661931
testis21 / 33044263
thymus5 / 8113161
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus21 / 23287890
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221789_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.6
Adipocyte4.1
AdrenalCortex4.15
Adrenalgland3.4
Amygdala4.45
Appendix3.9
AtrioventricularNode3
BDCA4+_DentriticCells24.45
Bonemarrow4
BronchialEpithelialCells4.15
CD105+_Endothelial11.05
CD14+_Monocytes8.55
CD19+_BCells(neg._sel.)17.35
CD33+_Myeloid13.85
CD34+19.5
CD4+_Tcells31.5
CD56+_NKCells19.65
CD71+_EarlyErythroid8.95
CD8+_Tcells46.4
CardiacMyocytes5.35
Caudatenucleus3.7
Cerebellum3.35
CerebellumPeduncles4.65
CiliaryGanglion2.8
CingulateCortex4.2
Colorectaladenocarcinoma4.55
DorsalRootGanglion3
FetalThyroid5.45
Fetalbrain4.15
Fetalliver3.5
Fetallung3.55
GlobusPallidus2.95
Heart5.15
Hypothalamus4.6
Kidney3.25
Leukemia_chronicMyelogenousK-5624.35
Leukemia_promyelocytic-HL-603.8
Leukemialymphoblastic(MOLT-4)5.85
Liver5.35
Lung5.6
Lymphnode6.95
Lymphoma_burkitts(Daudi)5.25
Lymphoma_burkitts(Raji)8.95
MedullaOblongata3.6
OccipitalLobe3.7
OlfactoryBulb3.25
Ovary2.7
Pancreas3.25
PancreaticIslet4.4
ParietalLobe4.25
Pituitary4.8
Placenta4.35
Pons3.75
PrefrontalCortex5.1
Prostate6.55
Salivarygland3.25
SkeletalMuscle4.45
Skin3.05
SmoothMuscle4.7
Spinalcord4.45
SubthalamicNucleus3.65
SuperiorCervicalGanglion4.2
TemporalLobe3.75
Testis3.6
TestisGermCell3.8
TestisIntersitial3.5
TestisLeydigCell4.05
TestisSeminiferousTubule3.55
Thalamus4
Thymus3.45
Thyroid10.3
Tongue3.9
Tonsil4.05
Trachea3.45
TrigeminalGanglion3.8
Uterus3.65
UterusCorpus3.4
WholeBlood4.55
Wholebrain3.6
colon4.15
pineal_day18.14
pineal_night11.82
retina10.825
small_intestine3.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10381_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.18 ± 0.77
Basal Forebrain8.07 ± 0.52
Basal Part of Pons8.07 ± 0.54
Cerebellar Cortex7.85 ± 0.42
Cerebellar Nuclei8.02 ± 0.2
Claustrum8.39 ± 0.62
Epithalamus7.3 ± 0.59
Frontal Lobe7.97 ± 0.55
Globus Pallidus8.26 ± 0.65
Hypothalamus7.86 ± 0.43
Insula7.74 ± 0.43
Limbic Lobe8.07 ± 0.66
Mesencephalon8.05 ± 0.59
Myelencephalon7.98 ± 0.57
Occipital Lobe7.93 ± 0.6
Parietal Lobe7.85 ± 0.45
Pontine Tegmentum7.79 ± 0.41
Striatum7.89 ± 0.64
Subthalamus8.04 ± 0.17
Temporal Lobe7.92 ± 0.57
Thalamus7.92 ± 0.52
White Matter7.85 ± 0.6
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rhot2CBCerebellum51.95
100
Rhot2CTXCerebral cortex100
100
Rhot2HIPHippocampal region100
100
Rhot2HPFHippocampal formation100
100
Rhot2HYHypothalamus72.83
70.99
Rhot2LSXLateral septal complex100
100
Rhot2MBMidbrain64.34
73.45
Rhot2MYMedulla44.73
71.04
Rhot2OLFOlfactory bulb100
100
Rhot2PPons44.83
61.52
Rhot2PALPallidum79.92
82.97
Rhot2RHPRetrohippocampal region100
100
Rhot2sAMYStriatum-like amygdalar nuclei100
100
Rhot2STRStriatum100
100
Rhot2STRdStriatum dorsal region100
100
Rhot2STRvStriatum ventral region100
100
Rhot2THThalamus92.36
96.85
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000259 19 526 544 ADLPEGVAVSGPSPAEFCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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