AutismKB 2.0

Annotation Detail for NOL3


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Basic Information Top
Gene Symbol:NOL3 ( ARC,FLJ35304,MYP,NOP,NOP30 )
Gene Full Name: nucleolar protein 3 (apoptosis repressor with CARD domain)
Band: 16q22.1
Quick LinksEntrez ID:8996; OMIM: 605235; Uniprot ID:NOL3_HUMAN; ENSEMBL ID: ENSG00000140939; HGNC ID: 7869
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus8 / 56401214
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult90 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor1 / 2638453
glioma3 / 10688328
head and neck tumor8 / 13630258
kidney tumor5 / 6895972
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal94 / 336030727
ovarian tumor1 / 7668213
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites5 / 40015124
bladder0 / 297570 
blood1 / 1234788
bone6 / 7165583
bone marrow0 / 488010 
brain29 / 110098926
cervix4 / 4817183
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye11 / 21105452
heart0 / 896260 
intestine10 / 23447242
kidney11 / 21177751
larynx2 / 2414582
liver3 / 20774314
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland8 / 15327152
mouth0 / 670520 
muscle7 / 10771564
nerve2 / 15768126
ovary1 / 1020519
pancreas15 / 21481269
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta8 / 28082528
prostate11 / 18934558
salivary gland4 / 20155198
skin8 / 21057437
spleen0 / 539520 
stomach2 / 9661920
testis1 / 3304423
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221566_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.15
Adipocyte21.95
AdrenalCortex8.3
Adrenalgland6.9
Amygdala7
Appendix6.2
AtrioventricularNode4.8
BDCA4+_DentriticCells5.85
Bonemarrow6.15
BronchialEpithelialCells14.9
CD105+_Endothelial5.55
CD14+_Monocytes6.35
CD19+_BCells(neg._sel.)5.8
CD33+_Myeloid6.75
CD34+6.8
CD4+_Tcells5.65
CD56+_NKCells6.4
CD71+_EarlyErythroid5.45
CD8+_Tcells5
CardiacMyocytes8.85
Caudatenucleus5.65
Cerebellum5
CerebellumPeduncles7.35
CiliaryGanglion4.35
CingulateCortex6.25
Colorectaladenocarcinoma10.55
DorsalRootGanglion4.75
FetalThyroid10.55
Fetalbrain5.75
Fetalliver5.2
Fetallung4.65
GlobusPallidus6.25
Heart141.4
Hypothalamus6.6
Kidney5.2
Leukemia_chronicMyelogenousK-5625.6
Leukemia_promyelocytic-HL-605.2
Leukemialymphoblastic(MOLT-4)4.6
Liver10.2
Lung13.85
Lymphnode4.75
Lymphoma_burkitts(Daudi)7.2
Lymphoma_burkitts(Raji)24.45
MedullaOblongata6.55
OccipitalLobe5.35
OlfactoryBulb4.95
Ovary4.1
Pancreas18.6
PancreaticIslet14.15
ParietalLobe7.1
Pituitary7.3
Placenta6.1
Pons6.65
PrefrontalCortex8.6
Prostate28.25
Salivarygland11.15
SkeletalMuscle31
Skin5.8
SmoothMuscle8.15
Spinalcord6.15
SubthalamicNucleus6.1
SuperiorCervicalGanglion7.3
TemporalLobe8.35
Testis5.15
TestisGermCell4.85
TestisIntersitial5.15
TestisLeydigCell6.1
TestisSeminiferousTubule5.15
Thalamus6.25
Thymus4.5
Thyroid10.4
Tongue15.2
Tonsil5.6
Trachea5.2
TrigeminalGanglion7.8
Uterus5.6
UterusCorpus6.95
WholeBlood6.55
Wholebrain9.95
colon7.15
pineal_day19.32
pineal_night24.06
retina10.575
small_intestine5.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11699_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.04 ± 0.61
Basal Forebrain4.39 ± 0.8
Basal Part of Pons4.95 ± 0.46
Cerebellar Cortex4.69 ± 0.41
Cerebellar Nuclei4.86 ± 0.35
Claustrum4.15 ± 0.85
Epithalamus5.19 ± 0.47
Frontal Lobe4.72 ± 0.48
Globus Pallidus5.28 ± 0.45
Hypothalamus5.36 ± 0.41
Insula4.55 ± 0.59
Limbic Lobe4.33 ± 0.59
Mesencephalon4.52 ± 0.53
Myelencephalon4.58 ± 0.61
Occipital Lobe3.98 ± 0.67
Parietal Lobe4.6 ± 0.47
Pontine Tegmentum4.63 ± 0.63
Striatum4.01 ± 0.51
Subthalamus4.75 ± 0.22
Temporal Lobe4.79 ± 0.52
Thalamus4.72 ± 0.48
White Matter4.17 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nol3CBCerebellum21.86
30.6
Nol3CTXCerebral cortex96.24
91.26
Nol3HIPHippocampal region62.76
100
Nol3HPFHippocampal formation76.3
100
Nol3HYHypothalamus100
100
Nol3LSXLateral septal complex38.1
29.28
Nol3MBMidbrain47.57
49.54
Nol3MYMedulla73.66
100
Nol3OLFOlfactory bulb100
100
Nol3PPons71.09
93.64
Nol3PALPallidum83.28
100
Nol3RHPRetrohippocampal region100
100
Nol3sAMYStriatum-like amygdalar nuclei100
100
Nol3STRStriatum58.82
52.83
Nol3STRdStriatum dorsal region45.94
40.22
Nol3STRvStriatum ventral region91.27
79.51
Nol3THThalamus65.55
69.52
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00027987 26 104 129 SYDPPCPGHWTPEAPGSGTTCPGLPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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