AutismKB 2.0

Annotation Detail for NAT1


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Basic Information Top
Gene Symbol:NAT1 ( AAC1,MNAT,NAT-1,NATI )
Gene Full Name: N-acetyltransferase 1 (arylamine N-acetyltransferase)
Band: 8p22
Quick LinksEntrez ID:9; OMIM: 108345; Uniprot ID:ARY1_HUMAN; ENSEMBL ID: ENSG00000171428; HGNC ID: 7645
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal35 / 336030710
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine5 / 23447221
kidney4 / 21177718
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph0 / 442700 
lymph node2 / 9161021
mammary gland5 / 15327132
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta6 / 28082521
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach2 / 9661920
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214440_at
Cell line Expression level Expression bar
721_B_lymphoblasts17.6
Adipocyte10.75
AdrenalCortex12.55
Adrenalgland9.65
Amygdala11.75
Appendix11.95
AtrioventricularNode9.05
BDCA4+_DentriticCells14.7
Bonemarrow11.3
BronchialEpithelialCells10.85
CD105+_Endothelial11.05
CD14+_Monocytes18.1
CD19+_BCells(neg._sel.)11.6
CD33+_Myeloid13.45
CD34+19.95
CD4+_Tcells11.55
CD56+_NKCells16.35
CD71+_EarlyErythroid10.7
CD8+_Tcells11.2
CardiacMyocytes15.9
Caudatenucleus9.95
Cerebellum9.05
CerebellumPeduncles13.35
CiliaryGanglion8.55
CingulateCortex11.95
Colorectaladenocarcinoma11.25
DorsalRootGanglion9.75
FetalThyroid10.95
Fetalbrain10.9
Fetalliver10.65
Fetallung7.65
GlobusPallidus8.35
Heart15.55
Hypothalamus11.65
Kidney10.6
Leukemia_chronicMyelogenousK-5629.9
Leukemia_promyelocytic-HL-6010
Leukemialymphoblastic(MOLT-4)9
Liver15.25
Lung12.2
Lymphnode9.5
Lymphoma_burkitts(Daudi)18
Lymphoma_burkitts(Raji)16.15
MedullaOblongata10.1
OccipitalLobe9.85
OlfactoryBulb8.6
Ovary8.35
Pancreas10
PancreaticIslet12
ParietalLobe13.25
Pituitary13.2
Placenta10.65
Pons11.1
PrefrontalCortex11.85
Prostate19.3
Salivarygland9
SkeletalMuscle19
Skin10.3
SmoothMuscle12.8
Spinalcord11.65
SubthalamicNucleus10.6
SuperiorCervicalGanglion22.95
TemporalLobe10.35
Testis9.65
TestisGermCell9.35
TestisIntersitial9.4
TestisLeydigCell11.25
TestisSeminiferousTubule9.6
Thalamus11.35
Thymus8.55
Thyroid13.9
Tongue14.75
Tonsil11
Trachea9.5
TrigeminalGanglion14.8
Uterus9.2
UterusCorpus10.4
WholeBlood27.05
Wholebrain9.2
colon48.85
pineal_day19.52
pineal_night18.02
retina13.8
small_intestine20.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16621_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.56 ± 1.08
Basal Forebrain2.13 ± 0.41
Basal Part of Pons1.8 ± 0.44
Cerebellar Cortex1.98 ± 0.7
Cerebellar Nuclei2.33 ± 0.67
Claustrum2.99 ± 1.07
Epithalamus2.1 ± 0.87
Frontal Lobe1.96 ± 0.69
Globus Pallidus2.52 ± 0.59
Hypothalamus2.17 ± 0.74
Insula2.34 ± 1.12
Limbic Lobe2.22 ± 0.78
Mesencephalon2.32 ± 0.77
Myelencephalon2.22 ± 0.75
Occipital Lobe2.4 ± 0.65
Parietal Lobe2.17 ± 0.78
Pontine Tegmentum2.23 ± 0.73
Striatum2.54 ± 0.95
Subthalamus2.34 ± 0.76
Temporal Lobe2.1 ± 0.73
Thalamus2.13 ± 0.66
White Matter2.23 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nat2CBCerebellum0.66
0.87
Nat2CTXCerebral cortex0.51
0.61
Nat2HIPHippocampal region0.24
0.33
Nat2HPFHippocampal formation0.27
0.36
Nat2HYHypothalamus1.97
2.59
Nat2LSXLateral septal complex0.14
0.2
Nat2MBMidbrain1.24
1.42
Nat2MYMedulla4.77
5.51
Nat2OLFOlfactory bulb1.42
1.44
Nat2PPons4.83
5.98
Nat2PALPallidum0.54
0.4
Nat2RHPRetrohippocampal region0.27
0.38
Nat2sAMYStriatum-like amygdalar nuclei0.24
0.17
Nat2STRStriatum0.39
0.39
Nat2STRdStriatum dorsal region0.25
0.23
Nat2STRvStriatum ventral region1.1
1.12
Nat2THThalamus0.36
0.35
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ARY1_HUMAN_1 9 1 9 MDIEAYLER PRIDE
PAp00024310 28 34 61 AVPFENLNIHCGDAMDLGLEAIFDQVVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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