AutismKB 2.0

Annotation Detail for SYT8


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Basic Information Top
Gene Symbol:SYT8 ( DKFZp434K0322 )
Gene Full Name: synaptotagmin VIII
Band: 11p15.5
Quick LinksEntrez ID:90019; OMIM: 607719; Uniprot ID:SYT8_HUMAN; ENSEMBL ID: ENSG00000149043; HGNC ID: 19264
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult23 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal23 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P36187
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.68 ± 1.09
Basal Forebrain2.29 ± 0.41
Basal Part of Pons1.89 ± 0.35
Cerebellar Cortex2.08 ± 0.8
Cerebellar Nuclei2.43 ± 0.64
Claustrum3.21 ± 1.01
Epithalamus1.82 ± 0.87
Frontal Lobe2.1 ± 0.74
Globus Pallidus2.76 ± 0.6
Hypothalamus2.3 ± 0.56
Insula2.06 ± 0.52
Limbic Lobe2.32 ± 0.79
Mesencephalon2.44 ± 0.8
Myelencephalon2.33 ± 0.72
Occipital Lobe2.34 ± 0.74
Parietal Lobe2.43 ± 0.92
Pontine Tegmentum2.44 ± 0.92
Striatum2.6 ± 0.93
Subthalamus2.51 ± 0.29
Temporal Lobe2.21 ± 0.71
Thalamus2.31 ± 0.67
White Matter2.33 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Syt8CBCerebellum0.48
0.83
Syt8CTXCerebral cortex0.98
1.56
Syt8HIPHippocampal region0.34
0.47
Syt8HPFHippocampal formation0.38
0.55
Syt8HYHypothalamus0.08
0.09
Syt8LSXLateral septal complex0.05
0
Syt8MBMidbrain0.28
0.4
Syt8MYMedulla0.75
0.76
Syt8OLFOlfactory bulb0.18
0.18
Syt8PPons0.15
0.37
Syt8PALPallidum0.13
0.17
Syt8RHPRetrohippocampal region0.38
0.49
Syt8sAMYStriatum-like amygdalar nuclei0.11
0.05
Syt8STRStriatum0.24
0.31
Syt8STRdStriatum dorsal region0.32
0.43
Syt8STRvStriatum ventral region0.09
0.07
Syt8THThalamus0.45
0.76
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018