AutismKB 2.0

Annotation Detail for BTBD6


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Basic Information Top
Gene Symbol:BTBD6 ( BDPL )
Gene Full Name: BTB (POZ) domain containing 6
Band: 14q32.33
Quick LinksEntrez ID:90135; OMIM: NA; Uniprot ID:BTBD6_HUMAN; ENSEMBL ID: ENSG00000184887; HGNC ID: 19897
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus17 / 56401230
neonate0 / 310970 
infant2 / 2362084
juvenile0 / 555560 
adult82 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor7 / 13630251
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor7 / 10312767
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal92 / 336030727
ovarian tumor5 / 7668265
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain17 / 110098915
cervix3 / 4817162
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye15 / 21105471
heart3 / 8962633
intestine4 / 23447217
kidney4 / 21177718
larynx0 / 241450 
liver3 / 20774314
lung14 / 33697441
lymph1 / 4427022
lymph node2 / 9161021
mammary gland5 / 15327132
mouth1 / 6705214
muscle9 / 10771583
nerve1 / 1576863
ovary4 / 10205139
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx6 / 41328145
pituitary gland2 / 16585120
placenta1 / 2808253
prostate13 / 18934568
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach0 / 966190 
testis9 / 33044227
thymus3 / 8113136
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P99614
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.51 ± 0.33
Basal Forebrain11.13 ± 0.2
Basal Part of Pons11.53 ± 0.25
Cerebellar Cortex11.37 ± 0.21
Cerebellar Nuclei10.95 ± 0.46
Claustrum11.3 ± 0.25
Epithalamus10.98 ± 0.43
Frontal Lobe11.39 ± 0.32
Globus Pallidus10.25 ± 0.38
Hypothalamus11.27 ± 0.27
Insula11.57 ± 0.23
Limbic Lobe11.37 ± 0.37
Mesencephalon11.13 ± 0.31
Myelencephalon11.23 ± 0.36
Occipital Lobe11.13 ± 0.32
Parietal Lobe11.35 ± 0.36
Pontine Tegmentum11.2 ± 0.3
Striatum11.23 ± 0.4
Subthalamus11.31 ± 0.3
Temporal Lobe11.43 ± 0.32
Thalamus11.13 ± 0.28
White Matter9.99 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Btbd6CBCerebellum26.9
31.67
Btbd6CTXCerebral cortex83.63
69.71
Btbd6HIPHippocampal region42.15
57.53
Btbd6HPFHippocampal formation50.98
56.31
Btbd6HYHypothalamus37.81
31.01
Btbd6LSXLateral septal complex34.91
25.62
Btbd6MBMidbrain34.9
32.45
Btbd6MYMedulla37.36
41.75
Btbd6OLFOlfactory bulb74.3
66.23
Btbd6PPons42.48
45.47
Btbd6PALPallidum48.43
47.92
Btbd6RHPRetrohippocampal region68.75
57.01
Btbd6sAMYStriatum-like amygdalar nuclei49.33
39.52
Btbd6STRStriatum49.59
37.67
Btbd6STRdStriatum dorsal region49.1
37.68
Btbd6STRvStriatum ventral region57.16
40.28
Btbd6THThalamus63.9
61.51
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018