AutismKB 2.0

Annotation Detail for TAF1B


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Basic Information Top
Gene Symbol:TAF1B ( MGC:9349,RAF1B,RAFI63,SL1,TAFI63 )
Gene Full Name: TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
Band: 2p25.1
Quick LinksEntrez ID:9014; OMIM: 604904; Uniprot ID:TAF1B_HUMAN; ENSEMBL ID: ENSG00000115750; HGNC ID: 11533
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult94 / 193912148
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor2 / 17290115
gastrointestinal tumor4 / 11936933
germ cell tumor5 / 26384518
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor18 / 96359186
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal75 / 336030722
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor14 / 125191111
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites2 / 4001549
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow1 / 4880120
brain19 / 110098917
cervix0 / 481710 
connective tissue12 / 14925580
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus2 / 2020998
eye2 / 2110549
heart1 / 8962611
intestine4 / 23447217
kidney6 / 21177728
larynx2 / 2414582
liver22 / 207743105
lung3 / 3369748
lymph0 / 442700 
lymph node3 / 9161032
mammary gland1 / 1532716
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary3 / 10205129
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta23 / 28082581
prostate4 / 18934521
salivary gland1 / 2015549
skin4 / 21057418
spleen1 / 5395218
stomach2 / 9661920
testis13 / 33044239
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216941_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts16.65
Adipocyte7.85
AdrenalCortex10.7
Adrenalgland7.45
Amygdala8
Appendix31.1
AtrioventricularNode9.8
BDCA4+_DentriticCells20.05
Bonemarrow8.75
BronchialEpithelialCells13.15
CD105+_Endothelial19
CD14+_Monocytes8.95
CD19+_BCells(neg._sel.)14.15
CD33+_Myeloid10.45
CD34+14.05
CD4+_Tcells9.2
CD56+_NKCells10.65
CD71+_EarlyErythroid8.25
CD8+_Tcells8.15
CardiacMyocytes12.2
Caudatenucleus7.5
Cerebellum6.75
CerebellumPeduncles10.05
CiliaryGanglion8.8
CingulateCortex8.65
Colorectaladenocarcinoma8.25
DorsalRootGanglion8.4
FetalThyroid9.1
Fetalbrain8.45
Fetalliver7.5
Fetallung6.6
GlobusPallidus6.65
Heart15.6
Hypothalamus9
Kidney7.85
Leukemia_chronicMyelogenousK-5627.25
Leukemia_promyelocytic-HL-607.65
Leukemialymphoblastic(MOLT-4)6.45
Liver11.65
Lung9.1
Lymphnode7.15
Lymphoma_burkitts(Daudi)24.45
Lymphoma_burkitts(Raji)13.25
MedullaOblongata7.45
OccipitalLobe7.1
OlfactoryBulb6.35
Ovary6.85
Pancreas6.75
PancreaticIslet9
ParietalLobe9.15
Pituitary9.8
Placenta7.8
Pons8.2
PrefrontalCortex9.95
Prostate9.65
Salivarygland6.85
SkeletalMuscle15
Skin8.2
SmoothMuscle9.15
Spinalcord8.5
SubthalamicNucleus8.15
SuperiorCervicalGanglion15.3
TemporalLobe7.8
Testis7.1
TestisGermCell6.25
TestisIntersitial8.1
TestisLeydigCell8.45
TestisSeminiferousTubule7.05
Thalamus8.6
Thymus6.05
Thyroid10.85
Tongue9.35
Tonsil8.3
Trachea6.9
TrigeminalGanglion12.05
Uterus6.4
UterusCorpus9.15
WholeBlood9.8
Wholebrain6.7
colon8.05
pineal_day12.32
pineal_night10.4
retina10.1
small_intestine7.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6952_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.13 ± 0.26
Basal Forebrain6.91 ± 0.17
Basal Part of Pons6.66 ± 0.27
Cerebellar Cortex7.04 ± 0.12
Cerebellar Nuclei6.53 ± 0.29
Claustrum7.03 ± 0.31
Epithalamus7.52 ± 0.31
Frontal Lobe6.75 ± 0.28
Globus Pallidus6.83 ± 0.25
Hypothalamus6.97 ± 0.29
Insula6.85 ± 0.27
Limbic Lobe6.87 ± 0.24
Mesencephalon6.86 ± 0.36
Myelencephalon6.78 ± 0.34
Occipital Lobe7 ± 0.23
Parietal Lobe6.85 ± 0.28
Pontine Tegmentum6.81 ± 0.29
Striatum6.45 ± 0.31
Subthalamus6.65 ± 0.18
Temporal Lobe6.78 ± 0.29
Thalamus6.52 ± 0.21
White Matter6.04 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Taf1bCBCerebellum5.35
5.11
Taf1bCTXCerebral cortex7.55
4.87
Taf1bHIPHippocampal region9.37
8.56
Taf1bHPFHippocampal formation9.7
7.85
Taf1bHYHypothalamus0.6
0.52
Taf1bLSXLateral septal complex0.27
0.36
Taf1bMBMidbrain2.59
2.13
Taf1bMYMedulla10.77
9.52
Taf1bOLFOlfactory bulb8.31
6.58
Taf1bPPons6.01
5.07
Taf1bPALPallidum1.57
1.2
Taf1bRHPRetrohippocampal region10.53
7.03
Taf1bsAMYStriatum-like amygdalar nuclei2.14
1.26
Taf1bSTRStriatum1.72
1.1
Taf1bSTRdStriatum dorsal region2.02
1.29
Taf1bSTRvStriatum ventral region1.26
0.77
Taf1bTHThalamus6.96
7.36
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
TAF1B_HUMAN_1 12 1 12 MDLEEAEEFKER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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