AutismKB 2.0

Annotation Detail for MPZL1


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Basic Information Top
Gene Symbol:MPZL1 ( FLJ21047,MPZL1b,PZR,PZR1b,PZRa,PZRb )
Gene Full Name: myelin protein zero-like 1
Band: 1q24.2
Quick LinksEntrez ID:9019; OMIM: 604376; Uniprot ID:MPZL1_HUMAN; ENSEMBL ID: ENSG00000197965; HGNC ID: 7226
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body15 / 70761211
blastocyst4 / 6231964
fetus76 / 564012134
neonate1 / 3109732
infant0 / 236200 
juvenile3 / 5555653
adult232 / 1939121119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor6 / 34366174
chondrosarcoma16 / 82823193
colorectal tumor23 / 114246201
esophageal tumor1 / 1729057
gastrointestinal tumor26 / 119369217
germ cell tumor46 / 263845174
glioma23 / 106883215
head and neck tumor21 / 136302154
kidney tumor5 / 6895972
leukemia4 / 9584241
liver tumor5 / 9635951
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal287 / 336030785
ovarian tumor9 / 76682117
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer15 / 102680146
retinoblastoma6 / 46356129
skin tumor11 / 12494988
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites9 / 40015224
bladder3 / 29757100
blood4 / 12347832
bone9 / 71655125
bone marrow2 / 4880140
brain76 / 110098969
cervix7 / 48171145
connective tissue16 / 149255107
ear3 / 16212185
embryonic tissue24 / 215722111
esophagus1 / 2020949
eye17 / 21105480
heart5 / 8962655
intestine40 / 234472170
kidney13 / 21177761
larynx0 / 241450 
liver10 / 20774348
lung23 / 33697468
lymph0 / 442700 
lymph node6 / 9161065
mammary gland24 / 153271156
mouth25 / 67052372
muscle5 / 10771546
nerve1 / 1576863
ovary10 / 10205197
pancreas17 / 21481279
parathyroid3 / 20539146
pharynx3 / 4132872
pituitary gland3 / 16585180
placenta19 / 28082567
prostate16 / 18934584
salivary gland0 / 201550 
skin28 / 210574132
spleen3 / 5395255
stomach14 / 96619144
testis47 / 330442142
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord0 / 136800 
uterus18 / 23287877
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210087_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.75
Adipocyte17.5
AdrenalCortex15.05
Adrenalgland7.6
Amygdala7.45
Appendix11.5
AtrioventricularNode10.4
BDCA4+_DentriticCells7.35
Bonemarrow10.35
BronchialEpithelialCells16.6
CD105+_Endothelial7.4
CD14+_Monocytes8.35
CD19+_BCells(neg._sel.)8.15
CD33+_Myeloid9.55
CD34+9.2
CD4+_Tcells5.65
CD56+_NKCells8.3
CD71+_EarlyErythroid7.2
CD8+_Tcells6.75
CardiacMyocytes111.05
Caudatenucleus7.05
Cerebellum6.5
CerebellumPeduncles8.85
CiliaryGanglion9.75
CingulateCortex7.8
Colorectaladenocarcinoma7.85
DorsalRootGanglion15.6
FetalThyroid7.7
Fetalbrain7.8
Fetalliver6.85
Fetallung13.25
GlobusPallidus6.35
Heart10.25
Hypothalamus7.7
Kidney7.8
Leukemia_chronicMyelogenousK-5627.35
Leukemia_promyelocytic-HL-606.9
Leukemialymphoblastic(MOLT-4)7.3
Liver10.85
Lung21.15
Lymphnode7.6
Lymphoma_burkitts(Daudi)9.95
Lymphoma_burkitts(Raji)11.4
MedullaOblongata7.7
OccipitalLobe6.7
OlfactoryBulb9.9
Ovary12.3
Pancreas6.5
PancreaticIslet10.9
ParietalLobe8.8
Pituitary15.2
Placenta31.2
Pons8.1
PrefrontalCortex8.7
Prostate13.45
Salivarygland7.45
SkeletalMuscle13.5
Skin12.45
SmoothMuscle145.5
Spinalcord8.45
SubthalamicNucleus10.35
SuperiorCervicalGanglion19.05
TemporalLobe7.4
Testis9.15
TestisGermCell7.95
TestisIntersitial6.75
TestisLeydigCell9.65
TestisSeminiferousTubule7.95
Thalamus7.9
Thymus6.65
Thyroid9.3
Tongue9.75
Tonsil15.25
Trachea18.5
TrigeminalGanglion12.75
Uterus6.45
UterusCorpus10.15
WholeBlood9.15
Wholebrain6.05
colon11.35
pineal_day8.76
pineal_night7.3
retina9.275
small_intestine7.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P11874
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.62 ± 0.35
Basal Forebrain5.96 ± 0.28
Basal Part of Pons5.59 ± 0.26
Cerebellar Cortex5.77 ± 0.28
Cerebellar Nuclei6.24 ± 0.36
Claustrum5.82 ± 0.63
Epithalamus6.16 ± 0.25
Frontal Lobe5.96 ± 0.39
Globus Pallidus6.96 ± 0.27
Hypothalamus6.31 ± 0.36
Insula5.94 ± 0.39
Limbic Lobe5.79 ± 0.43
Mesencephalon6.14 ± 0.36
Myelencephalon5.96 ± 0.42
Occipital Lobe5.89 ± 0.31
Parietal Lobe5.89 ± 0.37
Pontine Tegmentum6.08 ± 0.37
Striatum6.33 ± 0.42
Subthalamus6.34 ± 0.22
Temporal Lobe5.83 ± 0.35
Thalamus6.12 ± 0.32
White Matter5.66 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mpzl1CBCerebellum13.7
15.42
Mpzl1CTXCerebral cortex2.84
3.21
Mpzl1HIPHippocampal region3.22
3.97
Mpzl1HPFHippocampal formation3.4
3.75
Mpzl1HYHypothalamus1.65
1.82
Mpzl1LSXLateral septal complex2.53
2.52
Mpzl1MBMidbrain1.87
2.34
Mpzl1MYMedulla1.89
2.12
Mpzl1OLFOlfactory bulb3.83
4.13
Mpzl1PPons1.48
1.7
Mpzl1PALPallidum3.48
3.77
Mpzl1RHPRetrohippocampal region3.68
3.4
Mpzl1sAMYStriatum-like amygdalar nuclei2.07
2.18
Mpzl1STRStriatum2.72
2.81
Mpzl1STRdStriatum dorsal region2.93
3.1
Mpzl1STRvStriatum ventral region2.36
2.23
Mpzl1THThalamus2.4
2.71
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001870 15 199 213 DYTGCSTSESLSPVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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