AutismKB 2.0

Annotation Detail for FAM105B


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Basic Information Top
Gene Symbol:FAM105B ( FLJ34884 )
Gene Full Name: family with sequence similarity 105, member B
Band: 5p15.2
Quick LinksEntrez ID:90268; OMIM: NA; Uniprot ID:F105B_HUMAN; ENSEMBL ID: ENSG00000154124; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus20 / 56401235
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma7 / 8282384
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor11 / 26384541
glioma0 / 1068830 
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal78 / 336030723
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder0 / 297570 
blood5 / 12347840
bone9 / 71655125
bone marrow0 / 488010 
brain13 / 110098911
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye2 / 2110549
heart3 / 8962633
intestine3 / 23447212
kidney6 / 21177728
larynx1 / 2414541
liver5 / 20774324
lung10 / 33697429
lymph0 / 442700 
lymph node5 / 9161054
mammary gland2 / 15327113
mouth4 / 6705259
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate7 / 18934536
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis3 / 3304429
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P414446
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.6 ± 0.66
Basal Forebrain4.79 ± 0.24
Basal Part of Pons4.57 ± 0.42
Cerebellar Cortex4.98 ± 0.33
Cerebellar Nuclei4.57 ± 0.3
Claustrum4.22 ± 0.91
Epithalamus4.56 ± 0.47
Frontal Lobe4.51 ± 0.45
Globus Pallidus4.74 ± 0.29
Hypothalamus4.25 ± 0.35
Insula4.52 ± 0.5
Limbic Lobe4.53 ± 0.56
Mesencephalon4.53 ± 0.52
Myelencephalon4.48 ± 0.5
Occipital Lobe4.45 ± 0.4
Parietal Lobe4.64 ± 0.49
Pontine Tegmentum4.59 ± 0.61
Striatum4.39 ± 0.58
Subthalamus4.83 ± 0.28
Temporal Lobe4.53 ± 0.47
Thalamus4.53 ± 0.51
White Matter5.6 ± 0.6
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00062868 23 35 57 AAASGQPRPEMQCPAEHEEDMYR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018