AutismKB 2.0

Annotation Detail for ERI1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ERI1 ( 3'HEXO,HEXO,MGC35395,THEX1 )
Gene Full Name: exoribonuclease 1
Band: 8p23.1
Quick LinksEntrez ID:90459; OMIM: 608739; Uniprot ID:ERI1_HUMAN; ENSEMBL ID: ENSG00000104626; HGNC ID: 23994
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus20 / 56401235
neonate2 / 3109764
infant1 / 2362042
juvenile2 / 5555635
adult66 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor13 / 26384549
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal104 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor3 / 12494924
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood3 / 12347824
bone6 / 7165583
bone marrow5 / 48801102
brain17 / 110098915
cervix1 / 4817120
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine7 / 23447229
kidney2 / 2117779
larynx1 / 2414541
liver3 / 20774314
lung7 / 33697420
lymph0 / 442700 
lymph node17 / 91610185
mammary gland7 / 15327145
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta13 / 28082546
prostate5 / 18934526
salivary gland0 / 201550 
skin6 / 21057428
spleen1 / 5395218
stomach6 / 9661962
testis20 / 33044260
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus14 / 23287860
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P123466
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.73 ± 0.58
Basal Forebrain4.95 ± 0.17
Basal Part of Pons4.54 ± 0.36
Cerebellar Cortex4.62 ± 0.34
Cerebellar Nuclei4.74 ± 0.42
Claustrum4.6 ± 0.69
Epithalamus5.4 ± 0.42
Frontal Lobe4.48 ± 0.48
Globus Pallidus5.47 ± 0.5
Hypothalamus4.79 ± 0.43
Insula4.44 ± 0.29
Limbic Lobe4.58 ± 0.61
Mesencephalon4.74 ± 0.57
Myelencephalon4.66 ± 0.62
Occipital Lobe4.78 ± 0.48
Parietal Lobe4.71 ± 0.64
Pontine Tegmentum4.64 ± 0.58
Striatum5.16 ± 0.55
Subthalamus4.26 ± 0.44
Temporal Lobe4.57 ± 0.45
Thalamus4.63 ± 0.45
White Matter5.74 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Thex1CBCerebellum0.82
0.84
Thex1CTXCerebral cortex0.74
0.58
Thex1HIPHippocampal region0.97
0.72
Thex1HPFHippocampal formation0.68
0.53
Thex1HYHypothalamus0.36
0.31
Thex1LSXLateral septal complex0.21
0.46
Thex1MBMidbrain0.34
0.46
Thex1MYMedulla0.83
0.93
Thex1OLFOlfactory bulb1.42
2.9
Thex1PPons0.69
0.81
Thex1PALPallidum0.19
0.14
Thex1RHPRetrohippocampal region0.22
0.28
Thex1sAMYStriatum-like amygdalar nuclei0.12
0.22
Thex1STRStriatum0.19
0.2
Thex1STRdStriatum dorsal region0.2
0.2
Thex1STRvStriatum ventral region0.12
0.06
Thex1THThalamus0.49
0.48
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00072991 17 284 300 LGMDYDGRPHCGLDDSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018