Annotation Detail for SH2D2A
Basic Information Top
| Gene Symbol: | SH2D2A ( F2771,SCAP,TSAD,VRAP ) |
|---|---|
| Gene Full Name: | SH2 domain containing 2A |
| Band: | 1q23.1 |
| Quick Links | Entrez ID:9047; OMIM: 604514; Uniprot ID:SH22A_HUMAN; ENSEMBL ID: ENSG00000027869; HGNC ID: 10821 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.103527
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 4 / 564012 | 7 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 34 / 1939121 | 17 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 |  |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 2 / 263845 | 7 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 8 / 103127 | 77 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 55 / 3360307 | 16 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 20 / 123478 | 161 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 1 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 1 / 215722 | 4 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 4 / 211054 | 18 | |
| heart | 0 / 89626 | 0 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 2 / 211777 | 9 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 8 / 336974 | 23 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 7 / 96619 | 72 | |
| testis | 1 / 330442 | 3 | |
| thymus | 7 / 81131 | 86 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 207351_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.3 | |
| Adipocyte | 4.55 | |
| AdrenalCortex | 4.8 | |
| Adrenalgland | 4 | |
| Amygdala | 4.8 | |
| Appendix | 5 | |
| AtrioventricularNode | 5.45 | |
| BDCA4+_DentriticCells | 4.6 | |
| Bonemarrow | 4.75 | |
| BronchialEpithelialCells | 4.5 | |
| CD105+_Endothelial | 4.25 | |
| CD14+_Monocytes | 4.5 | |
| CD19+_BCells(neg._sel.) | 4.7 | |
| CD33+_Myeloid | 5.35 | |
| CD34+ | 5.9 | |
| CD4+_Tcells | 10 | |
| CD56+_NKCells | 146.35 | |
| CD71+_EarlyErythroid | 4.2 | |
| CD8+_Tcells | 14.35 | |
| CardiacMyocytes | 5.8 | |
| Caudatenucleus | 4.15 | |
| Cerebellum | 7.8 | |
| CerebellumPeduncles | 5.3 | |
| CiliaryGanglion | 3.2 | |
| CingulateCortex | 6.1 | |
| Colorectaladenocarcinoma | 4.65 | |
| DorsalRootGanglion | 3.6 | |
| FetalThyroid | 4.5 | |
| Fetalbrain | 4.65 | |
| Fetalliver | 8.85 | |
| Fetallung | 3.85 | |
| GlobusPallidus | 3.4 | |
| Heart | 7.25 | |
| Hypothalamus | 5.05 | |
| Kidney | 5.15 | |
| Leukemia_chronicMyelogenousK-562 | 4.6 | |
| Leukemia_promyelocytic-HL-60 | 4.05 | |
| Leukemialymphoblastic(MOLT-4) | 3.7 | |
| Liver | 6.05 | |
| Lung | 5.1 | |
| Lymphnode | 6.7 | |
| Lymphoma_burkitts(Daudi) | 5.85 | |
| Lymphoma_burkitts(Raji) | 7.05 | |
| MedullaOblongata | 4.2 | |
| OccipitalLobe | 4.1 | |
| OlfactoryBulb | 3.7 | |
| Ovary | 3.15 | |
| Pancreas | 3.75 | |
| PancreaticIslet | 4.9 | |
| ParietalLobe | 4.85 | |
| Pituitary | 5.3 | |
| Placenta | 4.7 | |
| Pons | 4.45 | |
| PrefrontalCortex | 5.7 | |
| Prostate | 5.45 | |
| Salivarygland | 3.7 | |
| SkeletalMuscle | 5.25 | |
| Skin | 3.55 | |
| SmoothMuscle | 5.1 | |
| Spinalcord | 4.9 | |
| SubthalamicNucleus | 4.2 | |
| SuperiorCervicalGanglion | 6.6 | |
| TemporalLobe | 4.2 | |
| Testis | 4 | |
| TestisGermCell | 3.85 | |
| TestisIntersitial | 3.9 | |
| TestisLeydigCell | 4.45 | |
| TestisSeminiferousTubule | 3.9 | |
| Thalamus | 4.7 | |
| Thymus | 5.65 | |
| Thyroid | 5.75 | |
| Tongue | 4.5 | |
| Tonsil | 5.7 | |
| Trachea | 5.7 | |
| TrigeminalGanglion | 4.55 | |
| Uterus | 3.75 | |
| UterusCorpus | 4.1 | |
| WholeBlood | 13.35 | |
| Wholebrain | 3.9 | |
| colon | 4.65 | |
| pineal_day | 447.02 |  |
| pineal_night | 512.24 | |
| retina | 5.375 | |
| small_intestine | 4.6 | |
- Probe name: CUST_14057_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.34 ± 0.26 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.62 ± 0.35 | |
| Basal Part of Pons | 7.57 ± 0.44 | |
| Cerebellar Cortex | 7.08 ± 0.21 | |
| Cerebellar Nuclei | 6.99 ± 0.15 | |
| Claustrum | 7.14 ± 0.28 | |
| Epithalamus | 7.42 ± 0.34 | |
| Frontal Lobe | 7.6 ± 0.49 | |
| Globus Pallidus | 8.24 ± 0.3 | |
| Hypothalamus | 7.45 ± 0.53 | |
| Insula | 7.42 ± 0.29 | |
| Limbic Lobe | 7.48 ± 0.48 | |
| Mesencephalon | 7.78 ± 0.53 | |
| Myelencephalon | 7.63 ± 0.45 | |
| Occipital Lobe | 7.35 ± 0.43 | |
| Parietal Lobe | 7.66 ± 0.45 | |
| Pontine Tegmentum | 7.38 ± 0.43 | |
| Striatum | 7.73 ± 0.43 | |
| Subthalamus | 7.09 ± 0.37 | |
| Temporal Lobe | 7.6 ± 0.41 | |
| Thalamus | 7.85 ± 0.45 | |
| White Matter | 6.52 ± 0.3 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Sh2d2a | CB | Cerebellum | 23.1 | |
| 27.28 | | |||
| Sh2d2a | CTX | Cerebral cortex | 32.76 | |
| 22.98 | | |||
| Sh2d2a | HIP | Hippocampal region | 19.72 | |
| 22.6 | | |||
| Sh2d2a | HPF | Hippocampal formation | 16.47 | |
| 16.41 | | |||
| Sh2d2a | HY | Hypothalamus | 24.12 | |
| 17.45 | | |||
| Sh2d2a | LSX | Lateral septal complex | 11.27 | |
| 7.79 | | |||
| Sh2d2a | MB | Midbrain | 15.11 | |
| 13.21 | | |||
| Sh2d2a | MY | Medulla | 20.83 | |
| 21.21 | | |||
| Sh2d2a | OLF | Olfactory bulb | 47.53 | |
| 36.71 | | |||
| Sh2d2a | P | Pons | 24.89 | |
| 24.64 | | |||
| Sh2d2a | PAL | Pallidum | 18.04 | |
| 14.53 | | |||
| Sh2d2a | RHP | Retrohippocampal region | 10.24 | |
| 7.25 | | |||
| Sh2d2a | sAMY | Striatum-like amygdalar nuclei | 20.28 | |
| 15.84 | | |||
| Sh2d2a | STR | Striatum | 20.02 | |
| 14.01 | | |||
| Sh2d2a | STRd | Striatum dorsal region | 17 | |
| 12.11 | | |||
| Sh2d2a | STRv | Striatum ventral region | 35.63 | |
| 22.36 | | |||
| Sh2d2a | TH | Thalamus | 29.59 | |
| 23.46 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00428836 | 12 | 133 | 144 | HVVLGEDSAHAR | Peptide Atlas |