AutismKB 2.0

Annotation Detail for SCRN2


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Basic Information Top
Gene Symbol:SCRN2 ( Ses2 )
Gene Full Name: secernin 2
Band: 17q21
Quick LinksEntrez ID:90507; OMIM: NA; Uniprot ID:SCRN2_HUMAN; ENSEMBL ID: ENSG00000141295; HGNC ID: 30381
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus24 / 56401242
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma8 / 10688374
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia10 / 95842104
liver tumor2 / 9635920
lung tumor8 / 10312777
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal121 / 336030736
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS19 / 125680151
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood12 / 12347897
bone6 / 7165583
bone marrow2 / 4880140
brain31 / 110098928
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye8 / 21105437
heart2 / 8962622
intestine6 / 23447225
kidney10 / 21177747
larynx0 / 241450 
liver8 / 20774338
lung15 / 33697444
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth1 / 6705214
muscle3 / 10771527
nerve3 / 15768190
ovary6 / 10205158
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta16 / 28082556
prostate8 / 18934542
salivary gland0 / 201550 
skin7 / 21057433
spleen1 / 5395218
stomach3 / 9661931
testis0 / 3304420 
thymus0 / 811310 
thyroid8 / 47473168
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus11 / 23287847
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P318593
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.13 ± 0.46
Basal Forebrain4.36 ± 0.38
Basal Part of Pons4.59 ± 0.47
Cerebellar Cortex4.61 ± 0.6
Cerebellar Nuclei4.08 ± 0.53
Claustrum3.62 ± 0.79
Epithalamus4.95 ± 0.8
Frontal Lobe4.43 ± 0.58
Globus Pallidus4.34 ± 0.46
Hypothalamus4.5 ± 0.68
Insula4.25 ± 0.48
Limbic Lobe4.22 ± 0.66
Mesencephalon4.26 ± 0.56
Myelencephalon4.38 ± 0.57
Occipital Lobe4.2 ± 0.53
Parietal Lobe4.34 ± 0.56
Pontine Tegmentum4.17 ± 0.61
Striatum4.46 ± 0.55
Subthalamus4.2 ± 0.95
Temporal Lobe4.3 ± 0.56
Thalamus4.36 ± 0.52
White Matter4.09 ± 0.67
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Scrn2CBCerebellum29.06
38.35
Scrn2CTXCerebral cortex50.49
36.64
Scrn2HIPHippocampal region22.77
24.91
Scrn2HPFHippocampal formation22.81
21.29
Scrn2HYHypothalamus27.91
19.91
Scrn2LSXLateral septal complex15.93
10.98
Scrn2MBMidbrain27.37
25.19
Scrn2MYMedulla48.83
48.07
Scrn2OLFOlfactory bulb46
34.05
Scrn2PPons41.49
40.04
Scrn2PALPallidum29.82
24.63
Scrn2RHPRetrohippocampal region22.68
15.8
Scrn2sAMYStriatum-like amygdalar nuclei28.57
20.06
Scrn2STRStriatum23.81
16.9
Scrn2STRdStriatum dorsal region20.06
14.65
Scrn2STRvStriatum ventral region36.77
23.9
Scrn2THThalamus33
27.05
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00005230 13 57 69 LQCTYIEVEQVSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018