AutismKB 2.0

Annotation Detail for CCDC74A


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Basic Information Top
Gene Symbol:CCDC74A ( FLJ40345 )
Gene Full Name: coiled-coil domain containing 74A
Band: 2q21.1
Quick LinksEntrez ID:90557; OMIM: NA; Uniprot ID:CC74A_HUMAN; ENSEMBL ID: ENSG00000163040; HGNC ID: 25197
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus11 / 56401219
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult28 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma4 / 7175555
non-neoplasia0 / 972500 
normal62 / 336030718
ovarian tumor8 / 76682104
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood2 / 12347816
bone1 / 7165513
bone marrow0 / 488010 
brain23 / 110098920
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye2 / 2110549
heart3 / 8962633
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung4 / 33697411
lymph4 / 4427090
lymph node0 / 916100 
mammary gland8 / 15327152
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary9 / 10205188
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis41 / 330442124
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P401718
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.58 ± 0.52
Basal Forebrain6.8 ± 0.47
Basal Part of Pons7.68 ± 0.35
Cerebellar Cortex6.4 ± 0.28
Cerebellar Nuclei6.73 ± 0.45
Claustrum6.59 ± 0.33
Epithalamus8.78 ± 1.09
Frontal Lobe7.25 ± 0.51
Globus Pallidus6.68 ± 0.78
Hypothalamus7.54 ± 0.6
Insula7.62 ± 0.48
Limbic Lobe7.31 ± 0.49
Mesencephalon6.84 ± 0.57
Myelencephalon7.06 ± 0.72
Occipital Lobe6.75 ± 0.66
Parietal Lobe7.1 ± 0.49
Pontine Tegmentum6.97 ± 0.54
Striatum7.07 ± 0.91
Subthalamus6.27 ± 0.6
Temporal Lobe7.18 ± 0.4
Thalamus6.52 ± 0.4
White Matter5.07 ± 0.46
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018