AutismKB 2.0

Annotation Detail for CLDN12


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Basic Information Top
Gene Symbol:CLDN12 ( - )
Gene Full Name: claudin 12
Band: 7q21.13
Quick LinksEntrez ID:9069; OMIM: 611232; Uniprot ID:CLD12_HUMAN; ENSEMBL ID: ENSG00000157224; HGNC ID: 2034
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P412515
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.01 ± 0.68
Basal Forebrain5.55 ± 0.42
Basal Part of Pons4.89 ± 0.45
Cerebellar Cortex5.29 ± 0.27
Cerebellar Nuclei4.72 ± 0.46
Claustrum5.22 ± 0.79
Epithalamus5.34 ± 0.34
Frontal Lobe5.05 ± 0.44
Globus Pallidus4.58 ± 0.63
Hypothalamus5.31 ± 0.61
Insula5.18 ± 0.52
Limbic Lobe5.13 ± 0.53
Mesencephalon5.2 ± 0.49
Myelencephalon5.19 ± 0.61
Occipital Lobe5.68 ± 0.48
Parietal Lobe5.22 ± 0.53
Pontine Tegmentum5.21 ± 0.65
Striatum5.79 ± 0.36
Subthalamus5.08 ± 0.61
Temporal Lobe5.13 ± 0.47
Thalamus5.45 ± 0.62
White Matter2.67 ± 0.6
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cldn12CBCerebellum4.36
4.17
Cldn12CTXCerebral cortex0.45
0.43
Cldn12HIPHippocampal region0.26
0.34
Cldn12HPFHippocampal formation0.25
0.25
Cldn12HYHypothalamus0.26
0.34
Cldn12LSXLateral septal complex0.18
0.14
Cldn12MBMidbrain0.33
0.3
Cldn12MYMedulla1.84
1.71
Cldn12OLFOlfactory bulb3.29
2.65
Cldn12PPons0.83
0.81
Cldn12PALPallidum0.17
0.22
Cldn12RHPRetrohippocampal region0.16
0.1
Cldn12sAMYStriatum-like amygdalar nuclei1.09
1.19
Cldn12STRStriatum0.29
0.24
Cldn12STRdStriatum dorsal region0.13
0.09
Cldn12STRvStriatum ventral region0.49
0.33
Cldn12THThalamus0.57
0.38
Peptide Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018