AutismKB 2.0

Annotation Detail for ZNF598


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Basic Information Top
Gene Symbol:ZNF598 ( DKFZp762F135,FLJ00086 )
Gene Full Name: zinc finger protein 598
Band: 16p13.3
Quick LinksEntrez ID:90850; OMIM: NA; Uniprot ID:ZN598_HUMAN; ENSEMBL ID: ENSG00000167962; HGNC ID: 28079
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult68 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor8 / 34366232
chondrosarcoma2 / 8282324
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor14 / 26384553
glioma12 / 106883112
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor13 / 103127126
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal77 / 336030722
ovarian tumor3 / 7668239
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer3 / 10268029
retinoblastoma7 / 46356151
skin tumor19 / 124949152
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites6 / 40015149
bladder1 / 2975733
blood5 / 12347840
bone1 / 7165513
bone marrow0 / 488010 
brain23 / 110098920
cervix8 / 48171166
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye20 / 21105494
heart4 / 8962644
intestine11 / 23447246
kidney1 / 2117774
larynx1 / 2414541
liver2 / 2077439
lung25 / 33697474
lymph1 / 4427022
lymph node1 / 9161010
mammary gland2 / 15327113
mouth2 / 6705229
muscle1 / 1077159
nerve1 / 1576863
ovary5 / 10205148
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate4 / 18934521
salivary gland1 / 2015549
skin20 / 21057494
spleen0 / 539520 
stomach4 / 9661941
testis4 / 33044212
thymus0 / 811310 
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus14 / 23287860
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2303_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.54 ± 1.16
Basal Forebrain1.88 ± 0.56
Basal Part of Pons1.97 ± 0.78
Cerebellar Cortex1.72 ± 0.73
Cerebellar Nuclei2.43 ± 0.51
Claustrum2.61 ± 0.9
Epithalamus1.47 ± 0.77
Frontal Lobe1.92 ± 0.94
Globus Pallidus3.02 ± 0.63
Hypothalamus1.87 ± 1.12
Insula1.96 ± 0.77
Limbic Lobe2.08 ± 0.93
Mesencephalon2.18 ± 0.95
Myelencephalon2.05 ± 0.86
Occipital Lobe2.1 ± 1.07
Parietal Lobe2.17 ± 0.95
Pontine Tegmentum2.2 ± 1.01
Striatum2.6 ± 1.02
Subthalamus1.91 ± 0.96
Temporal Lobe2.04 ± 0.95
Thalamus1.94 ± 0.78
White Matter2.07 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp598CBCerebellum88.18
100
Zfp598CTXCerebral cortex85.42
62.02
Zfp598HIPHippocampal region51.32
64.4
Zfp598HPFHippocampal formation60.84
63.61
Zfp598HYHypothalamus93.82
72.65
Zfp598LSXLateral septal complex100
76.63
Zfp598MBMidbrain72.53
58.9
Zfp598MYMedulla76.96
79.6
Zfp598OLFOlfactory bulb100
100
Zfp598PPons78.06
74.92
Zfp598PALPallidum73.55
63.9
Zfp598RHPRetrohippocampal region85.15
65.38
Zfp598sAMYStriatum-like amygdalar nuclei77.43
57.73
Zfp598STRStriatum79.85
57.71
Zfp598STRdStriatum dorsal region68.69
46.74
Zfp598STRvStriatum ventral region100
83.66
Zfp598THThalamus83.09
64.46
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009691 11 247 257 CSTEQFTHAFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018