AutismKB 2.0

Annotation Detail for HN1L


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Basic Information Top
Gene Symbol:HN1L ( C16orf34,FLJ13092,KIAA1426,L11 )
Gene Full Name: hematological and neurological expressed 1-like
Band: 16p13.3
Quick LinksEntrez ID:90861; OMIM: NA; Uniprot ID:HN1L_HUMAN; ENSEMBL ID: ENSG00000206053; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst22 / 62319353
fetus58 / 564012102
neonate6 / 31097192
infant1 / 2362042
juvenile7 / 55556125
adult220 / 1939121113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor18 / 94178191
cervical tumor7 / 34366203
chondrosarcoma7 / 8282384
colorectal tumor21 / 114246183
esophageal tumor2 / 17290115
gastrointestinal tumor14 / 119369117
germ cell tumor57 / 263845216
glioma6 / 10688356
head and neck tumor44 / 136302322
kidney tumor8 / 68959116
leukemia7 / 9584273
liver tumor14 / 96359145
lung tumor9 / 10312787
lymphoma4 / 7175555
non-neoplasia7 / 9725071
normal303 / 336030790
ovarian tumor5 / 7668265
pancreatic tumor20 / 104616191
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer39 / 102680379
retinoblastoma4 / 4635686
skin tumor9 / 12494972
soft tissue/muscle tissue tumor19 / 125191151
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites6 / 40015149
bladder3 / 29757100
blood5 / 12347840
bone8 / 71655111
bone marrow3 / 4880161
brain100 / 110098990
cervix7 / 48171145
connective tissue9 / 14925560
ear3 / 16212185
embryonic tissue38 / 215722176
esophagus2 / 2020998
eye13 / 21105461
heart5 / 8962655
intestine27 / 234472115
kidney16 / 21177775
larynx0 / 241450 
liver18 / 20774386
lung29 / 33697486
lymph4 / 4427090
lymph node8 / 9161087
mammary gland22 / 153271143
mouth33 / 67052492
muscle11 / 107715102
nerve0 / 157680 
ovary8 / 10205178
pancreas24 / 214812111
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta33 / 280825117
prostate51 / 189345269
salivary gland5 / 20155248
skin19 / 21057490
spleen4 / 5395274
stomach7 / 9661972
testis51 / 330442154
thymus10 / 81131123
thyroid9 / 47473189
tonsil1 / 1699958
trachea23 / 52413438
umbilical cord3 / 13680219
uterus39 / 232878167
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212115_at
Cell line Expression level Expression bar
721_B_lymphoblasts169.8
Adipocyte28.75
AdrenalCortex19.4
Adrenalgland31.75
Amygdala12.55
Appendix25.55
AtrioventricularNode12.45
BDCA4+_DentriticCells37.2
Bonemarrow29.05
BronchialEpithelialCells197.2
CD105+_Endothelial225.8
CD14+_Monocytes11.5
CD19+_BCells(neg._sel.)34.7
CD33+_Myeloid26.25
CD34+173.95
CD4+_Tcells30.2
CD56+_NKCells36.4
CD71+_EarlyErythroid101.6
CD8+_Tcells23.5
CardiacMyocytes44.25
Caudatenucleus20
Cerebellum24.15
CerebellumPeduncles31.9
CiliaryGanglion7.8
CingulateCortex10.95
Colorectaladenocarcinoma56.55
DorsalRootGanglion18.05
FetalThyroid47.55
Fetalbrain18.95
Fetalliver50.25
Fetallung42.05
GlobusPallidus8.9
Heart23.55
Hypothalamus61.8
Kidney33.35
Leukemia_chronicMyelogenousK-56285.25
Leukemia_promyelocytic-HL-6084.7
Leukemialymphoblastic(MOLT-4)76.4
Liver38.85
Lung38.75
Lymphnode25.2
Lymphoma_burkitts(Daudi)71.7
Lymphoma_burkitts(Raji)43.15
MedullaOblongata26.85
OccipitalLobe25
OlfactoryBulb34.3
Ovary15.05
Pancreas39.05
PancreaticIslet52.25
ParietalLobe25.9
Pituitary35
Placenta96.75
Pons23.2
PrefrontalCortex16.15
Prostate125.7
Salivarygland32.8
SkeletalMuscle14.95
Skin9
SmoothMuscle53.65
Spinalcord107.45
SubthalamicNucleus12.3
SuperiorCervicalGanglion16.8
TemporalLobe10.85
Testis34.6
TestisGermCell21.95
TestisIntersitial24.55
TestisLeydigCell24.2
TestisSeminiferousTubule25.7
Thalamus39.15
Thymus61.35
Thyroid61.75
Tongue25.4
Tonsil36.55
Trachea46.75
TrigeminalGanglion11.4
Uterus26.05
UterusCorpus13
WholeBlood20.95
Wholebrain22.7
colon77.75
pineal_day10.16
pineal_night9.66
retina80.225
small_intestine70.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P434900
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.15 ± 0.69
Basal Forebrain6.25 ± 0.63
Basal Part of Pons6.31 ± 0.58
Cerebellar Cortex6.46 ± 0.19
Cerebellar Nuclei7.83 ± 0.93
Claustrum5.9 ± 0.56
Epithalamus6.59 ± 0.71
Frontal Lobe6.2 ± 0.94
Globus Pallidus8 ± 0.64
Hypothalamus5.76 ± 0.49
Insula5.58 ± 0.52
Limbic Lobe5.6 ± 0.66
Mesencephalon6.28 ± 1.04
Myelencephalon6.2 ± 0.85
Occipital Lobe6.3 ± 0.79
Parietal Lobe5.95 ± 0.98
Pontine Tegmentum6.4 ± 0.59
Striatum5.69 ± 0.78
Subthalamus7.37 ± 0.39
Temporal Lobe5.78 ± 0.7
Thalamus6.48 ± 0.71
White Matter9.18 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
D17Ertd441eCBCerebellum3.94
4.43
D17Ertd441eCTXCerebral cortex1.58
1.36
D17Ertd441eHIPHippocampal region2.61
3.1
D17Ertd441eHPFHippocampal formation2.35
2.52
D17Ertd441eHYHypothalamus0.74
0.72
D17Ertd441eLSXLateral septal complex0.37
0.34
D17Ertd441eMBMidbrain0.78
1.07
D17Ertd441eMYMedulla4.99
5.33
D17Ertd441eOLFOlfactory bulb2.63
2.02
D17Ertd441ePPons1.86
1.95
D17Ertd441ePALPallidum0.93
0.76
D17Ertd441eRHPRetrohippocampal region1.79
1.66
D17Ertd441esAMYStriatum-like amygdalar nuclei1.33
1.25
D17Ertd441eSTRStriatum0.88
0.9
D17Ertd441eSTRdStriatum dorsal region0.91
1.04
D17Ertd441eSTRvStriatum ventral region0.69
0.51
D17Ertd441eTHThalamus0.89
1.17
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
HN1L_HUMAN_1 11 1 11 MFQVPDSEGGR PRIDE
HN1L_HUMAN_113 12 113 124 DHVFLCEGEEPK PRIDE
HN1L_HUMAN_132 11 132 142 SIPAGAEPGEK PRIDE
HN1L_HUMAN_146 20 146 165 KAGPAKEQEPMPTVDSHEPR PRIDE
HN1L_HUMAN_68 14 68 81 GSGIFDESTPVQTR PRIDE
HN1L_HUMAN_68 23 68 90 GSGIFDESTPVQTRQHLNPPGGK PRIDE
HN1L_HUMAN_82 23 82 104 QHLNPPGGKTSDIFGSPVTATSR PRIDE
HN1L_HUMAN_82 9 82 90 QHLNPPGGK PRIDE
PAp00001631 16 113 128 DHVFLCEGEEPKSDLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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