AutismKB 2.0

Annotation Detail for DHX57


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Basic Information Top
Gene Symbol:DHX57 ( DDX57,FLJ32861 )
Gene Full Name: DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
Band: 2p22.1
Quick LinksEntrez ID:90957; OMIM: NA; Uniprot ID:DHX57_HUMAN; ENSEMBL ID: ENSG00000163214; HGNC ID: 20086
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus15 / 56401226
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult40 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor5 / 9635951
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal70 / 336030720
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor8 / 12494964
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine8 / 23447234
kidney3 / 21177714
larynx0 / 241450 
liver6 / 20774328
lung9 / 33697426
lymph0 / 442700 
lymph node5 / 9161054
mammary gland5 / 15327132
mouth1 / 6705214
muscle0 / 1077150 
nerve2 / 15768126
ovary5 / 10205148
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin9 / 21057442
spleen1 / 5395218
stomach1 / 9661910
testis15 / 33044245
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord2 / 13680146
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213420_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.9
Adipocyte5.3
AdrenalCortex6.4
Adrenalgland4.65
Amygdala5.2
Appendix5.6
AtrioventricularNode4.25
BDCA4+_DentriticCells5.65
Bonemarrow5.5
BronchialEpithelialCells5.35
CD105+_Endothelial5.35
CD14+_Monocytes8.05
CD19+_BCells(neg._sel.)5.8
CD33+_Myeloid7.1
CD34+6.75
CD4+_Tcells5.55
CD56+_NKCells6.35
CD71+_EarlyErythroid5.05
CD8+_Tcells5
CardiacMyocytes7.35
Caudatenucleus4.9
Cerebellum4.4
CerebellumPeduncles6.15
CiliaryGanglion4.15
CingulateCortex5.6
Colorectaladenocarcinoma5.35
DorsalRootGanglion5.05
FetalThyroid5.3
Fetalbrain7.85
Fetalliver4.75
Fetallung4.4
GlobusPallidus4.1
Heart7.4
Hypothalamus5.6
Kidney4.7
Leukemia_chronicMyelogenousK-5624.9
Leukemia_promyelocytic-HL-604.7
Leukemialymphoblastic(MOLT-4)4.4
Liver7.95
Lung5.7
Lymphnode4.45
Lymphoma_burkitts(Daudi)7
Lymphoma_burkitts(Raji)7.55
MedullaOblongata4.85
OccipitalLobe4.8
OlfactoryBulb4.3
Ovary3.7
Pancreas4.4
PancreaticIslet5.8
ParietalLobe5.95
Pituitary6.4
Placenta5.3
Pons5.25
PrefrontalCortex6.6
Prostate6
Salivarygland4.55
SkeletalMuscle7.1
Skin4.55
SmoothMuscle6.05
Spinalcord5.8
SubthalamicNucleus5
SuperiorCervicalGanglion6.4
TemporalLobe5.1
Testis4.65
TestisGermCell4.4
TestisIntersitial5.1
TestisLeydigCell5.5
TestisSeminiferousTubule7.9
Thalamus5.6
Thymus4
Thyroid6.4
Tongue5.95
Tonsil5.3
Trachea4.55
TrigeminalGanglion5.85
Uterus4.2
UterusCorpus4.95
WholeBlood6.05
Wholebrain4.25
colon5.3
pineal_day6.78
pineal_night6.46
retina6.425
small_intestine5.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P120109
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.54 ± 0.79
Basal Forebrain3.13 ± 0.46
Basal Part of Pons3.13 ± 0.36
Cerebellar Cortex3.35 ± 0.44
Cerebellar Nuclei3.21 ± 0.6
Claustrum3.58 ± 0.58
Epithalamus3.36 ± 0.5
Frontal Lobe3.3 ± 0.52
Globus Pallidus2.98 ± 0.61
Hypothalamus3.26 ± 0.36
Insula3.33 ± 0.39
Limbic Lobe3.36 ± 0.47
Mesencephalon3.37 ± 0.59
Myelencephalon3.27 ± 0.51
Occipital Lobe3.58 ± 0.48
Parietal Lobe3.42 ± 0.56
Pontine Tegmentum3.47 ± 0.53
Striatum3.16 ± 0.68
Subthalamus3.58 ± 0.27
Temporal Lobe3.29 ± 0.51
Thalamus3.36 ± 0.53
White Matter2.92 ± 1.01
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00076669 22 652 673 RLEGDTALQGVSHIIVDEVHER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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