AutismKB 2.0

Annotation Detail for CREB3L1


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Basic Information Top
Gene Symbol:CREB3L1 ( OASIS )
Gene Full Name: cAMP responsive element binding protein 3-like 1
Band: 11p11.2
Quick LinksEntrez ID:90993; OMIM: NA; Uniprot ID:CR3L1_HUMAN; ENSEMBL ID: ENSG00000157613; HGNC ID: 18856
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus14 / 56401224
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult83 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor42 / 114246367
esophageal tumor0 / 172900 
gastrointestinal tumor21 / 119369175
germ cell tumor4 / 26384515
glioma5 / 10688346
head and neck tumor2 / 13630214
kidney tumor7 / 68959101
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor35 / 103127339
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal74 / 336030722
ovarian tumor7 / 7668291
pancreatic tumor19 / 104616181
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer8 / 10268077
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood0 / 1234780 
bone4 / 7165555
bone marrow0 / 488010 
brain9 / 11009898
cervix1 / 4817120
connective tissue6 / 14925540
ear1 / 1621261
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye5 / 21105423
heart4 / 8962644
intestine56 / 234472238
kidney8 / 21177737
larynx0 / 241450 
liver1 / 2077434
lung48 / 336974142
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary9 / 10205188
pancreas27 / 214812125
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta8 / 28082528
prostate8 / 18934542
salivary gland0 / 201550 
skin13 / 21057461
spleen2 / 5395237
stomach23 / 96619238
testis3 / 3304429
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213059_at
Cell line Expression level Expression bar
721_B_lymphoblasts39.8
Adipocyte114.85
AdrenalCortex118.4
Adrenalgland196.75
Amygdala77.5
Appendix71.1
AtrioventricularNode55
BDCA4+_DentriticCells15.55
Bonemarrow149.1
BronchialEpithelialCells49.05
CD105+_Endothelial38.3
CD14+_Monocytes11.05
CD19+_BCells(neg._sel.)27.35
CD33+_Myeloid47.3
CD34+37.7
CD4+_Tcells39.2
CD56+_NKCells23.05
CD71+_EarlyErythroid66.25
CD8+_Tcells23.8
CardiacMyocytes122
Caudatenucleus87.55
Cerebellum71.8
CerebellumPeduncles87.65
CiliaryGanglion49.1
CingulateCortex76.25
Colorectaladenocarcinoma63.75
DorsalRootGanglion53.45
FetalThyroid66.95
Fetalbrain72.4
Fetalliver71.25
Fetallung62.5
GlobusPallidus51.9
Heart338.25
Hypothalamus73.15
Kidney86.7
Leukemia_chronicMyelogenousK-562107.45
Leukemia_promyelocytic-HL-6062.55
Leukemialymphoblastic(MOLT-4)61.1
Liver93.7
Lung164
Lymphnode63.75
Lymphoma_burkitts(Daudi)92.85
Lymphoma_burkitts(Raji)73.45
MedullaOblongata68.2
OccipitalLobe65.4
OlfactoryBulb55.25
Ovary46.7
Pancreas84.4
PancreaticIslet177.85
ParietalLobe101.15
Pituitary87.75
Placenta96.1
Pons84.7
PrefrontalCortex74.65
Prostate278
Salivarygland57.85
SkeletalMuscle90.35
Skin57.65
SmoothMuscle176.95
Spinalcord75.6
SubthalamicNucleus64.6
SuperiorCervicalGanglion121
TemporalLobe64.55
Testis100.8
TestisGermCell61.8
TestisIntersitial61.25
TestisLeydigCell94.85
TestisSeminiferousTubule62.85
Thalamus73.25
Thymus57.2
Thyroid85.35
Tongue77.15
Tonsil91.1
Trachea262.05
TrigeminalGanglion69.55
Uterus57.15
UterusCorpus120.8
WholeBlood59.3
Wholebrain62.15
colon128.4
pineal_day66.82
pineal_night75.5
retina84.575
small_intestine65.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6659_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.91 ± 0.94
Basal Forebrain2.2 ± 0.34
Basal Part of Pons2.23 ± 0.77
Cerebellar Cortex2.26 ± 0.78
Cerebellar Nuclei2.69 ± 0.7
Claustrum3.18 ± 0.72
Epithalamus2.19 ± 0.63
Frontal Lobe2.66 ± 0.68
Globus Pallidus2.48 ± 0.56
Hypothalamus2.66 ± 0.31
Insula2.88 ± 0.37
Limbic Lobe2.74 ± 0.73
Mesencephalon2.67 ± 0.84
Myelencephalon2.55 ± 0.7
Occipital Lobe2.2 ± 0.73
Parietal Lobe2.47 ± 0.82
Pontine Tegmentum2.62 ± 0.61
Striatum2.12 ± 0.87
Subthalamus2.58 ± 1.12
Temporal Lobe2.64 ± 0.67
Thalamus2.51 ± 0.58
White Matter2.8 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Creb3l1CBCerebellum32.73
26.1
Creb3l1CTXCerebral cortex17.84
14.61
Creb3l1HIPHippocampal region7.29
3.61
Creb3l1HPFHippocampal formation8.59
6.4
Creb3l1HYHypothalamus7.76
5.17
Creb3l1LSXLateral septal complex1.75
0.95
Creb3l1MBMidbrain7.36
5.02
Creb3l1MYMedulla23.56
16.29
Creb3l1OLFOlfactory bulb19.69
12.46
Creb3l1PPons11.32
8.23
Creb3l1PALPallidum4.3
3.03
Creb3l1RHPRetrohippocampal region10.68
9.75
Creb3l1sAMYStriatum-like amygdalar nuclei5.37
2.8
Creb3l1STRStriatum2.49
1.41
Creb3l1STRdStriatum dorsal region0.87
0.5
Creb3l1STRvStriatum ventral region7.42
3.97
Creb3l1THThalamus3.05
1.92
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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