AutismKB 2.0

Annotation Detail for CCDC34


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Basic Information Top
Gene Symbol:CCDC34 ( NY-REN-41,RAMA3 )
Gene Full Name: coiled-coil domain containing 34
Band: 11p14.1
Quick LinksEntrez ID:91057; OMIM: 612324; Uniprot ID:CCD34_HUMAN; ENSEMBL ID: ENSG00000109881; HGNC ID: 25079
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus9 / 56401215
neonate0 / 310970 
infant2 / 2362084
juvenile2 / 5555635
adult60 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor2 / 2638457
glioma3 / 10688328
head and neck tumor12 / 13630288
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal66 / 336030719
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood10 / 12347880
bone3 / 7165541
bone marrow0 / 488010 
brain19 / 110098917
cervix4 / 4817183
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine2 / 2344728
kidney6 / 21177728
larynx0 / 241450 
liver1 / 2077434
lung7 / 33697420
lymph0 / 442700 
lymph node4 / 9161043
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary4 / 10205139
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate3 / 18934515
salivary gland1 / 2015549
skin2 / 2105749
spleen0 / 539520 
stomach11 / 96619113
testis9 / 33044227
thymus0 / 811310 
thyroid12 / 47473252
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P203773
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.47 ± 0.96
Basal Forebrain2.04 ± 0.2
Basal Part of Pons1.7 ± 0.34
Cerebellar Cortex1.85 ± 0.68
Cerebellar Nuclei2.33 ± 0.71
Claustrum2.81 ± 0.78
Epithalamus1.72 ± 0.69
Frontal Lobe1.83 ± 0.56
Globus Pallidus2.51 ± 0.34
Hypothalamus2.05 ± 0.6
Insula1.91 ± 0.5
Limbic Lobe2.01 ± 0.58
Mesencephalon2.13 ± 0.62
Myelencephalon2.02 ± 0.62
Occipital Lobe2.04 ± 0.57
Parietal Lobe2.04 ± 0.64
Pontine Tegmentum2.08 ± 0.66
Striatum2.19 ± 0.6
Subthalamus2.13 ± 0.62
Temporal Lobe1.93 ± 0.65
Thalamus2.01 ± 0.61
White Matter2.55 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2810027O19RikCBCerebellum3.36
4.39
2810027O19RikCTXCerebral cortex1.1
1.21
2810027O19RikHIPHippocampal region1.47
1.56
2810027O19RikHPFHippocampal formation1.16
1.23
2810027O19RikHYHypothalamus0.78
0.66
2810027O19RikLSXLateral septal complex0.25
0.29
2810027O19RikMBMidbrain3.51
5.54
2810027O19RikMYMedulla8.1
9.96
2810027O19RikOLFOlfactory bulb4.53
3.89
2810027O19RikPPons2.42
2.67
2810027O19RikPALPallidum1.68
1.65
2810027O19RikRHPRetrohippocampal region0.57
0.76
2810027O19RiksAMYStriatum-like amygdalar nuclei1.14
0.91
2810027O19RikSTRStriatum0.85
0.74
2810027O19RikSTRdStriatum dorsal region0.65
0.67
2810027O19RikSTRvStriatum ventral region1.82
1.21
2810027O19RikTHThalamus1.62
1.6
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018