AutismKB 2.0

Annotation Detail for SEC22C


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Basic Information Top
Gene Symbol:SEC22C ( DKFZp761F2321,MGC13261,MGC5373,SEC22L3 )
Gene Full Name: SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
Band: 3p22.1
Quick LinksEntrez ID:9117; OMIM: 604028; Uniprot ID:SC22C_HUMAN; ENSEMBL ID: ENSG00000093183; HGNC ID: 16828
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst5 / 6231980
fetus45 / 56401279
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult102 / 193912152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor2 / 3436658
chondrosarcoma9 / 82823108
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor9 / 26384534
glioma2 / 10688318
head and neck tumor6 / 13630244
kidney tumor4 / 6895958
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal224 / 336030766
ovarian tumor3 / 7668239
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor5 / 12494940
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder2 / 2975767
blood2 / 12347816
bone5 / 7165569
bone marrow1 / 4880120
brain55 / 110098949
cervix2 / 4817141
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue19 / 21572288
esophagus0 / 202090 
eye12 / 21105456
heart6 / 8962666
intestine9 / 23447238
kidney13 / 21177761
larynx0 / 241450 
liver4 / 20774319
lung11 / 33697432
lymph0 / 442700 
lymph node3 / 9161032
mammary gland9 / 15327158
mouth4 / 6705259
muscle2 / 10771518
nerve0 / 157680 
ovary5 / 10205148
pancreas26 / 214812121
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta19 / 28082567
prostate9 / 18934547
salivary gland1 / 2015549
skin17 / 21057480
spleen1 / 5395218
stomach6 / 9661962
testis20 / 33044260
thymus3 / 8113136
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus12 / 23287851
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P205874
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.91 ± 0.28
Basal Forebrain8.08 ± 0.17
Basal Part of Pons8.07 ± 0.2
Cerebellar Cortex8.03 ± 0.13
Cerebellar Nuclei8.33 ± 0.19
Claustrum7.82 ± 0.46
Epithalamus8.38 ± 0.29
Frontal Lobe8.15 ± 0.26
Globus Pallidus8.63 ± 0.13
Hypothalamus8.18 ± 0.24
Insula8.21 ± 0.24
Limbic Lobe7.91 ± 0.25
Mesencephalon8.18 ± 0.32
Myelencephalon8.08 ± 0.28
Occipital Lobe7.93 ± 0.23
Parietal Lobe8.01 ± 0.27
Pontine Tegmentum8.11 ± 0.2
Striatum7.93 ± 0.22
Subthalamus8.33 ± 0.27
Temporal Lobe8.1 ± 0.22
Thalamus8.15 ± 0.23
White Matter9.28 ± 0.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sec22cHYHypothalamus25.82
19.42
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018