AutismKB 2.0

Annotation Detail for INA


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Basic Information Top
Gene Symbol:INA ( FLJ18662,FLJ57501,MGC12702,NEF5,NF-66,TXBP-1 )
Gene Full Name: internexin neuronal intermediate filament protein, alpha
Band: 10q24.33
Quick LinksEntrez ID:9118; OMIM: 605338; Uniprot ID:AINX_HUMAN; ENSEMBL ID: ENSG00000148798; HGNC ID: 6057
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus47 / 56401283
neonate0 / 310970 
infant3 / 23620127
juvenile2 / 5555635
adult47 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor12 / 26384545
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal134 / 336030739
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain87 / 110098979
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye24 / 211054113
heart1 / 8962611
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve2 / 15768126
ovary2 / 10205119
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis16 / 33044248
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204465_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.75
Adipocyte4.45
AdrenalCortex5.6
Adrenalgland3.9
Amygdala360.05
Appendix10.2
AtrioventricularNode3.35
BDCA4+_DentriticCells4.1
Bonemarrow4.3
BronchialEpithelialCells3.95
CD105+_Endothelial3.7
CD14+_Monocytes4.25
CD19+_BCells(neg._sel.)4.05
CD33+_Myeloid5.2
CD34+4.75
CD4+_Tcells4.55
CD56+_NKCells4.55
CD71+_EarlyErythroid3.9
CD8+_Tcells3.85
CardiacMyocytes4.95
Caudatenucleus271.1
Cerebellum390.3
CerebellumPeduncles441.4
CiliaryGanglion3.05
CingulateCortex605.8
Colorectaladenocarcinoma4.2
DorsalRootGanglion12.15
FetalThyroid4.2
Fetalbrain1685.05
Fetalliver3.65
Fetallung3.35
GlobusPallidus247.2
Heart6.2
Hypothalamus1026.85
Kidney3.8
Leukemia_chronicMyelogenousK-5625.35
Leukemia_promyelocytic-HL-603.75
Leukemialymphoblastic(MOLT-4)10.15
Liver6.55
Lung4.6
Lymphnode3.6
Lymphoma_burkitts(Daudi)5.85
Lymphoma_burkitts(Raji)5.95
MedullaOblongata555.35
OccipitalLobe488.4
OlfactoryBulb3.35
Ovary4.35
Pancreas5.15
PancreaticIslet41.55
ParietalLobe407.4
Pituitary406.8
Placenta4.2
Pons371.2
PrefrontalCortex887.35
Prostate4.9
Salivarygland3.4
SkeletalMuscle6.3
Skin3.55
SmoothMuscle5.9
Spinalcord81.1
SubthalamicNucleus507.95
SuperiorCervicalGanglion7.15
TemporalLobe488.1
Testis5.3
TestisGermCell4.65
TestisIntersitial4.3
TestisLeydigCell8.15
TestisSeminiferousTubule6.7
Thalamus1271.5
Thymus3.35
Thyroid4.95
Tongue5.85
Tonsil4.25
Trachea3.55
TrigeminalGanglion5.2
Uterus3.35
UterusCorpus6.55
WholeBlood6.5
Wholebrain615.65
colon3.95
pineal_day902.3
pineal_night897.26
retina111.825
small_intestine4.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11460_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.77 ± 0.51
Basal Forebrain10.09 ± 0.47
Basal Part of Pons11.27 ± 0.24
Cerebellar Cortex10.2 ± 0.47
Cerebellar Nuclei11.45 ± 0.39
Claustrum9.88 ± 0.48
Epithalamus9.46 ± 1.11
Frontal Lobe10.35 ± 0.74
Globus Pallidus10.19 ± 0.78
Hypothalamus10.78 ± 0.27
Insula10.01 ± 0.34
Limbic Lobe9.76 ± 0.76
Mesencephalon10.18 ± 0.69
Myelencephalon10.16 ± 0.93
Occipital Lobe10.32 ± 0.63
Parietal Lobe10.62 ± 0.6
Pontine Tegmentum10.22 ± 0.51
Striatum9.35 ± 0.63
Subthalamus11.33 ± 0.32
Temporal Lobe10.2 ± 0.48
Thalamus10.59 ± 0.62
White Matter6.48 ± 0.64
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
InaCBCerebellum96.61
100
InaCTXCerebral cortex100
100
InaHIPHippocampal region100
100
InaHPFHippocampal formation100
100
InaHYHypothalamus100
100
InaLSXLateral septal complex100
100
InaMBMidbrain100
100
InaMYMedulla99.68
100
InaOLFOlfactory bulb100
100
InaPPons100
100
InaPALPallidum91
100
InaRHPRetrohippocampal region100
100
InasAMYStriatum-like amygdalar nuclei100
100
InaSTRStriatum100
100
InaSTRdStriatum dorsal region100
100
InaSTRvStriatum ventral region100
100
InaTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011508 22 46 67 SNVASSAACSSASSLGLGLAYR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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