AutismKB 2.0

Annotation Detail for SLC16A5


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Basic Information Top
Gene Symbol:SLC16A5 ( MCT5,MCT6 )
Gene Full Name: solute carrier family 16, member 5 (monocarboxylic acid transporter 6)
Band: 17q25.1
Quick LinksEntrez ID:9121; OMIM: 603879; Uniprot ID:MOT6_HUMAN; ENSEMBL ID: ENSG00000170190; HGNC ID: 10926
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult67 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor19 / 119369159
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor7 / 13630251
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal56 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites14 / 40015349
bladder1 / 2975733
blood4 / 12347832
bone1 / 7165513
bone marrow0 / 488010 
brain8 / 11009897
cervix6 / 48171124
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye2 / 2110549
heart3 / 8962633
intestine11 / 23447246
kidney3 / 21177714
larynx1 / 2414541
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth5 / 6705274
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta10 / 28082535
prostate5 / 18934526
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach7 / 9661972
testis6 / 33044218
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206599_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.6
Adipocyte3.7
AdrenalCortex3.85
Adrenalgland3.1
Amygdala4
Appendix3.7
AtrioventricularNode2.8
BDCA4+_DentriticCells4.1
Bonemarrow3.75
BronchialEpithelialCells3.7
CD105+_Endothelial3.75
CD14+_Monocytes6.85
CD19+_BCells(neg._sel.)3.95
CD33+_Myeloid4.85
CD34+4.85
CD4+_Tcells4.05
CD56+_NKCells4.4
CD71+_EarlyErythroid3.45
CD8+_Tcells3.6
CardiacMyocytes5.25
Caudatenucleus3.35
Cerebellum3
CerebellumPeduncles4.2
CiliaryGanglion2.9
CingulateCortex3.8
Colorectaladenocarcinoma25
DorsalRootGanglion2.85
FetalThyroid3.6
Fetalbrain3.7
Fetalliver3.2
Fetallung3.1
GlobusPallidus2.7
Heart4.75
Hypothalamus4.05
Kidney3
Leukemia_chronicMyelogenousK-5623.35
Leukemia_promyelocytic-HL-603.25
Leukemialymphoblastic(MOLT-4)3
Liver4.95
Lung8.95
Lymphnode3.25
Lymphoma_burkitts(Daudi)4.7
Lymphoma_burkitts(Raji)5.25
MedullaOblongata3.4
OccipitalLobe3.35
OlfactoryBulb2.95
Ovary2.4
Pancreas2.95
PancreaticIslet3.95
ParietalLobe3.85
Pituitary4.35
Placenta3.9
Pons3.55
PrefrontalCortex4.6
Prostate5.05
Salivarygland2.9
SkeletalMuscle4.3
Skin2.85
SmoothMuscle4.2
Spinalcord3.95
SubthalamicNucleus3.3
SuperiorCervicalGanglion4.2
TemporalLobe3.35
Testis3.2
TestisGermCell3.1
TestisIntersitial3.1
TestisLeydigCell3.65
TestisSeminiferousTubule3.2
Thalamus3.8
Thymus2.95
Thyroid4.95
Tongue3.75
Tonsil3.6
Trachea3.1
TrigeminalGanglion3.65
Uterus3.05
UterusCorpus3.4
WholeBlood4.6
Wholebrain3.2
colon3.7
pineal_day4.62
pineal_night4.54
retina4.475
small_intestine3.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P159125
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.19 ± 0.82
Basal Forebrain3.71 ± 0.67
Basal Part of Pons3.46 ± 0.4
Cerebellar Cortex3.73 ± 0.33
Cerebellar Nuclei3.68 ± 0.4
Claustrum3.2 ± 0.55
Epithalamus5.45 ± 1
Frontal Lobe3.15 ± 0.91
Globus Pallidus4.13 ± 0.59
Hypothalamus3.78 ± 0.77
Insula3.48 ± 0.42
Limbic Lobe3.01 ± 0.68
Mesencephalon3.3 ± 0.75
Myelencephalon3.41 ± 0.75
Occipital Lobe2.95 ± 0.99
Parietal Lobe2.9 ± 0.83
Pontine Tegmentum3.07 ± 0.96
Striatum3.81 ± 1.14
Subthalamus2.89 ± 0.34
Temporal Lobe3.09 ± 0.85
Thalamus3.04 ± 0.85
White Matter3.67 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slc16a5CBCerebellum0
0
Slc16a5CTXCerebral cortex0
0
Slc16a5HIPHippocampal region0
0
Slc16a5HPFHippocampal formation0
0
Slc16a5HYHypothalamus0
0
Slc16a5LSXLateral septal complex0
0
Slc16a5MBMidbrain0
0
Slc16a5MYMedulla0
0
Slc16a5OLFOlfactory bulb0
0
Slc16a5PPons0
0
Slc16a5PALPallidum0
0
Slc16a5RHPRetrohippocampal region0
0
Slc16a5sAMYStriatum-like amygdalar nuclei0
0
Slc16a5STRStriatum0
0
Slc16a5STRdStriatum dorsal region0
0
Slc16a5STRvStriatum ventral region0
0
Slc16a5THThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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