AutismKB 2.0

Annotation Detail for LMF2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LMF2 ( TMEM112B,TMEM153 )
Gene Full Name: lipase maturation factor 2
Band: 22q13.33
Quick LinksEntrez ID:91289; OMIM: NA; Uniprot ID:LMF2_HUMAN; ENSEMBL ID: ENSG00000100258; HGNC ID: 25096
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst3 / 6231948
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult92 / 193912147
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma7 / 8282384
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor6 / 26384522
glioma13 / 106883121
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia7 / 9584273
liver tumor3 / 9635931
lung tumor6 / 10312758
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal129 / 336030738
ovarian tumor5 / 7668265
pancreatic tumor21 / 104616200
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer5 / 10268048
retinoblastoma4 / 4635686
skin tumor44 / 124949352
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood8 / 12347864
bone7 / 7165597
bone marrow6 / 48801122
brain39 / 110098935
cervix3 / 4817162
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye13 / 21105461
heart1 / 8962611
intestine10 / 23447242
kidney12 / 21177756
larynx0 / 241450 
liver3 / 20774314
lung11 / 33697432
lymph4 / 4427090
lymph node7 / 9161076
mammary gland6 / 15327139
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary8 / 10205178
pancreas22 / 214812102
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate11 / 18934558
salivary gland0 / 201550 
skin47 / 210574223
spleen1 / 5395218
stomach5 / 9661951
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 31837_at
Cell line Expression level Expression bar
721_B_lymphoblasts18.25
Adipocyte17.05
AdrenalCortex10.35
Adrenalgland9.55
Amygdala10.3
Appendix11.6
AtrioventricularNode7.15
BDCA4+_DentriticCells39.5
Bonemarrow9.35
BronchialEpithelialCells11.7
CD105+_Endothelial17.15
CD14+_Monocytes17.1
CD19+_BCells(neg._sel.)18.8
CD33+_Myeloid33.2
CD34+20.15
CD4+_Tcells67.1
CD56+_NKCells43.6
CD71+_EarlyErythroid20.7
CD8+_Tcells49.45
CardiacMyocytes14.65
Caudatenucleus8.45
Cerebellum7.75
CerebellumPeduncles10.1
CiliaryGanglion6.7
CingulateCortex11.65
Colorectaladenocarcinoma10.4
DorsalRootGanglion6.25
FetalThyroid30.05
Fetalbrain7.75
Fetalliver8.45
Fetallung8.7
GlobusPallidus5.35
Heart17.05
Hypothalamus9.55
Kidney7.85
Leukemia_chronicMyelogenousK-5629.05
Leukemia_promyelocytic-HL-607.1
Leukemialymphoblastic(MOLT-4)8.4
Liver26.3
Lung23.2
Lymphnode21.25
Lymphoma_burkitts(Daudi)11.55
Lymphoma_burkitts(Raji)10.9
MedullaOblongata8.1
OccipitalLobe8
OlfactoryBulb9.7
Ovary5.4
Pancreas12.9
PancreaticIslet15.6
ParietalLobe7.75
Pituitary13.4
Placenta11.05
Pons6.85
PrefrontalCortex9.95
Prostate19.8
Salivarygland7.2
SkeletalMuscle11.7
Skin6.8
SmoothMuscle14.5
Spinalcord13.9
SubthalamicNucleus7.15
SuperiorCervicalGanglion10.2
TemporalLobe7.3
Testis9.85
TestisGermCell8.95
TestisIntersitial7.7
TestisLeydigCell9.65
TestisSeminiferousTubule8.65
Thalamus9.75
Thymus13.3
Thyroid32.3
Tongue9.5
Tonsil14.5
Trachea9.55
TrigeminalGanglion7.2
Uterus13.7
UterusCorpus17.9
WholeBlood11.9
Wholebrain8.95
colon10.05
pineal_day12.46
pineal_night12.46
retina13.425
small_intestine9.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_554_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.52 ± 0.82
Basal Forebrain1.84 ± 0.2
Basal Part of Pons2.25 ± 0.55
Cerebellar Cortex2.45 ± 0.63
Cerebellar Nuclei2.3 ± 0.67
Claustrum2.5 ± 0.79
Epithalamus2.13 ± 0.67
Frontal Lobe2.33 ± 0.65
Globus Pallidus1.99 ± 0.78
Hypothalamus2.58 ± 1.33
Insula1.96 ± 0.73
Limbic Lobe2.2 ± 0.54
Mesencephalon2.3 ± 0.71
Myelencephalon2.29 ± 0.6
Occipital Lobe2.03 ± 0.71
Parietal Lobe2.18 ± 0.63
Pontine Tegmentum2.16 ± 0.68
Striatum2.04 ± 0.6
Subthalamus2.28 ± 0.73
Temporal Lobe2.29 ± 0.65
Thalamus2.19 ± 0.62
White Matter2.15 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem153CBCerebellum9.09
11.3
Tmem153CTXCerebral cortex7.79
5.98
Tmem153HIPHippocampal region4.53
4.46
Tmem153HPFHippocampal formation6.7
6
Tmem153HYHypothalamus0.46
0.35
Tmem153LSXLateral septal complex0.61
0.4
Tmem153MBMidbrain1.6
1.7
Tmem153MYMedulla6.5
6.57
Tmem153OLFOlfactory bulb9.8
7.87
Tmem153PPons2.3
2.65
Tmem153PALPallidum2.13
1.66
Tmem153RHPRetrohippocampal region8.96
7.1
Tmem153sAMYStriatum-like amygdalar nuclei1.14
0.67
Tmem153STRStriatum1.26
1
Tmem153STRdStriatum dorsal region1.06
0.93
Tmem153STRvStriatum ventral region2.13
1.41
Tmem153THThalamus2.79
2.25
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved