AutismKB 2.0

Annotation Detail for CCNB2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CCNB2 ( HsT17299 )
Gene Full Name: cyclin B2
Band: 15q22.2
Quick LinksEntrez ID:9133; OMIM: 602755; Uniprot ID:CCNB2_HUMAN; ENSEMBL ID: ENSG00000157456; HGNC ID: 1580
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst11 / 62319176
fetus32 / 56401256
neonate0 / 310970 
infant14 / 23620592
juvenile8 / 55556143
adult102 / 193912152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma5 / 17475286
breast (mammary gland) tumor16 / 94178169
cervical tumor6 / 34366174
chondrosarcoma7 / 8282384
colorectal tumor9 / 11424678
esophageal tumor12 / 17290694
gastrointestinal tumor16 / 119369134
germ cell tumor21 / 26384579
glioma5 / 10688346
head and neck tumor6 / 13630244
kidney tumor1 / 6895914
leukemia7 / 9584273
liver tumor10 / 96359103
lung tumor15 / 103127145
lymphoma9 / 71755125
non-neoplasia0 / 972500 
normal157 / 336030746
ovarian tumor5 / 7668265
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS31 / 125680246
prostate cancer6 / 10268058
retinoblastoma15 / 46356323
skin tumor7 / 12494956
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites8 / 40015199
bladder5 / 29757168
blood12 / 12347897
bone6 / 7165583
bone marrow4 / 4880181
brain36 / 110098932
cervix6 / 48171124
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue35 / 215722162
esophagus12 / 20209593
eye20 / 21105494
heart4 / 8962644
intestine15 / 23447263
kidney3 / 21177714
larynx0 / 241450 
liver14 / 20774367
lung19 / 33697456
lymph5 / 44270112
lymph node9 / 9161098
mammary gland22 / 153271143
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary6 / 10205158
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta24 / 28082585
prostate6 / 18934531
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach7 / 9661972
testis36 / 330442108
thymus11 / 81131135
thyroid5 / 47473105
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus16 / 23287868
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202705_at
Cell line Expression level Expression bar
721_B_lymphoblasts716.35
Adipocyte9.5
AdrenalCortex12.7
Adrenalgland8.4
Amygdala9.05
Appendix22.9
AtrioventricularNode8.3
BDCA4+_DentriticCells14.55
Bonemarrow100.2
BronchialEpithelialCells77.6
CD105+_Endothelial1093.3
CD14+_Monocytes10.05
CD19+_BCells(neg._sel.)9.9
CD33+_Myeloid50.6
CD34+380.65
CD4+_Tcells10.2
CD56+_NKCells10.45
CD71+_EarlyErythroid654.2
CD8+_Tcells9.05
CardiacMyocytes141.5
Caudatenucleus8.8
Cerebellum8.15
CerebellumPeduncles11.4
CiliaryGanglion10.55
CingulateCortex9.85
Colorectaladenocarcinoma203.75
DorsalRootGanglion12.8
FetalThyroid10.35
Fetalbrain9.65
Fetalliver82.25
Fetallung10.35
GlobusPallidus7.25
Heart12.35
Hypothalamus10.25
Kidney9.35
Leukemia_chronicMyelogenousK-562214.85
Leukemia_promyelocytic-HL-60211.1
Leukemialymphoblastic(MOLT-4)284.1
Liver15.55
Lung11.45
Lymphnode8.3
Lymphoma_burkitts(Daudi)351.65
Lymphoma_burkitts(Raji)58.45
MedullaOblongata8.95
OccipitalLobe8.6
OlfactoryBulb7.6
Ovary7.4
Pancreas11.3
PancreaticIslet11.1
ParietalLobe11.3
Pituitary10.95
Placenta15.35
Pons12.8
PrefrontalCortex10.95
Prostate10.6
Salivarygland8.7
SkeletalMuscle13.05
Skin9.95
SmoothMuscle12
Spinalcord10
SubthalamicNucleus9.2
SuperiorCervicalGanglion18.95
TemporalLobe9.7
Testis259.45
TestisGermCell192.95
TestisIntersitial365.25
TestisLeydigCell196.7
TestisSeminiferousTubule186.8
Thalamus9.65
Thymus157.3
Thyroid11.4
Tongue11.1
Tonsil53.4
Trachea10.9
TrigeminalGanglion12.15
Uterus7.55
UterusCorpus10.55
WholeBlood9.7
Wholebrain7.9
colon44.85
pineal_day11.24
pineal_night10.64
retina10.85
small_intestine39.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15864_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.72 ± 1.04
Basal Forebrain1.97 ± 0.38
Basal Part of Pons1.6 ± 0.39
Cerebellar Cortex1.92 ± 0.81
Cerebellar Nuclei2.23 ± 0.74
Claustrum2.71 ± 0.79
Epithalamus1.66 ± 0.82
Frontal Lobe1.82 ± 0.79
Globus Pallidus2.24 ± 0.33
Hypothalamus2 ± 0.67
Insula1.95 ± 1.22
Limbic Lobe2 ± 0.69
Mesencephalon2.11 ± 0.69
Myelencephalon2 ± 0.71
Occipital Lobe1.97 ± 0.61
Parietal Lobe2 ± 0.71
Pontine Tegmentum2.1 ± 0.82
Striatum2.12 ± 0.61
Subthalamus2.04 ± 0.68
Temporal Lobe1.94 ± 0.71
Thalamus1.91 ± 0.7
White Matter2.03 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ccnb2CBCerebellum0.14
0.5
Ccnb2CTXCerebral cortex0.23
0.55
Ccnb2HIPHippocampal region0.34
0.65
Ccnb2HPFHippocampal formation0.41
0.9
Ccnb2HYHypothalamus1.07
1.43
Ccnb2LSXLateral septal complex0.07
0.09
Ccnb2MBMidbrain1.37
2.84
Ccnb2MYMedulla0.5
1.61
Ccnb2OLFOlfactory bulb2.67
4.53
Ccnb2PPons2.55
6.61
Ccnb2PALPallidum0.91
1.88
Ccnb2RHPRetrohippocampal region0.61
1.37
Ccnb2sAMYStriatum-like amygdalar nuclei2.32
3.91
Ccnb2STRStriatum0.78
1.19
Ccnb2STRdStriatum dorsal region0.05
0.09
Ccnb2STRvStriatum ventral region2.87
3.83
Ccnb2THThalamus0.06
0.12
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CCNB2_HUMAN_264 8 264 271 PLPLHFLR PRIDE
PAp00076848 18 6 23 RPTVSSDLENIDTGVNSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved