AutismKB 2.0

Annotation Detail for LRP5L


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Basic Information Top
Gene Symbol:LRP5L ( DKFZp434O0213 )
Gene Full Name: low density lipoprotein receptor-related protein 5-like
Band: 22q11.23
Quick LinksEntrez ID:91355; OMIM: NA; Uniprot ID:LRP5L_HUMAN; ENSEMBL ID: ENSG00000100068; HGNC ID: 25323
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult17 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia5 / 9584252
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal11 / 33603073
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood5 / 12347840
bone1 / 7165513
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine6 / 23447225
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung2 / 3369745
lymph1 / 4427022
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis2 / 3304426
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214873_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.1
Adipocyte9.65
AdrenalCortex10.5
Adrenalgland8.6
Amygdala8.2
Appendix12.7
AtrioventricularNode8
BDCA4+_DentriticCells8.65
Bonemarrow10.1
BronchialEpithelialCells8.7
CD105+_Endothelial9.1
CD14+_Monocytes9.6
CD19+_BCells(neg._sel.)9.75
CD33+_Myeloid11.65
CD34+11.2
CD4+_Tcells9.5
CD56+_NKCells10.15
CD71+_EarlyErythroid8.9
CD8+_Tcells8.95
CardiacMyocytes14.2
Caudatenucleus8.35
Cerebellum7.6
CerebellumPeduncles11.6
CiliaryGanglion8.9
CingulateCortex9.35
Colorectaladenocarcinoma9.15
DorsalRootGanglion8.7
FetalThyroid10.3
Fetalbrain8.35
Fetalliver8.3
Fetallung7.45
GlobusPallidus7.25
Heart14.4
Hypothalamus9.8
Kidney9.35
Leukemia_chronicMyelogenousK-5628.35
Leukemia_promyelocytic-HL-608.4
Leukemialymphoblastic(MOLT-4)7.25
Liver16.65
Lung10.35
Lymphnode8.5
Lymphoma_burkitts(Daudi)12.9
Lymphoma_burkitts(Raji)15.55
MedullaOblongata8.25
OccipitalLobe7.8
OlfactoryBulb7.25
Ovary6.75
Pancreas8.85
PancreaticIslet10.05
ParietalLobe10.4
Pituitary10.3
Placenta8.55
Pons9.35
PrefrontalCortex11
Prostate11
Salivarygland8
SkeletalMuscle13.6
Skin9
SmoothMuscle10.6
Spinalcord9.95
SubthalamicNucleus8.85
SuperiorCervicalGanglion21.05
TemporalLobe8.7
Testis7.9
TestisGermCell7.35
TestisIntersitial7.85
TestisLeydigCell9.5
TestisSeminiferousTubule7.7
Thalamus9.75
Thymus7.3
Thyroid11.85
Tongue12
Tonsil9.3
Trachea7.9
TrigeminalGanglion12.95
Uterus7.6
UterusCorpus11.55
WholeBlood9.7
Wholebrain7.35
colon9.6
pineal_day10.46
pineal_night10.3
retina11.275
small_intestine9.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7607_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.16 ± 0.91
Basal Forebrain2.87 ± 0.65
Basal Part of Pons3.2 ± 0.67
Cerebellar Cortex2.48 ± 0.67
Cerebellar Nuclei2.89 ± 0.75
Claustrum2.99 ± 0.53
Epithalamus2.68 ± 0.69
Frontal Lobe2.86 ± 0.73
Globus Pallidus3.2 ± 0.83
Hypothalamus2.86 ± 0.43
Insula2.57 ± 0.74
Limbic Lobe2.73 ± 0.74
Mesencephalon2.86 ± 0.8
Myelencephalon2.86 ± 0.77
Occipital Lobe3.25 ± 0.59
Parietal Lobe2.93 ± 0.8
Pontine Tegmentum2.73 ± 0.7
Striatum2.89 ± 0.65
Subthalamus3.13 ± 0.84
Temporal Lobe2.8 ± 0.76
Thalamus2.83 ± 0.73
White Matter3.95 ± 0.51
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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