AutismKB 2.0

Annotation Detail for DEPDC7


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Basic Information Top
Gene Symbol:DEPDC7 ( TR2,dJ85M6.4 )
Gene Full Name: DEP domain containing 7
Band: 11p13
Quick LinksEntrez ID:91614; OMIM: 612294; Uniprot ID:DEPD7_HUMAN; ENSEMBL ID: ENSG00000121690; HGNC ID: 29899
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult14 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal36 / 336030710
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow2 / 4880140
brain9 / 11009898
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney5 / 21177723
larynx0 / 241450 
liver10 / 20774348
lung1 / 3369742
lymph0 / 442700 
lymph node5 / 9161054
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis8 / 33044224
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6895_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.43 ± 1.01
Basal Forebrain3.88 ± 0.74
Basal Part of Pons3.4 ± 0.63
Cerebellar Cortex3.01 ± 0.63
Cerebellar Nuclei4.28 ± 0.86
Claustrum3.54 ± 0.68
Epithalamus3.08 ± 0.96
Frontal Lobe3.67 ± 0.82
Globus Pallidus5.16 ± 0.4
Hypothalamus3.32 ± 0.94
Insula3.26 ± 0.56
Limbic Lobe3.48 ± 0.78
Mesencephalon3.94 ± 0.89
Myelencephalon3.65 ± 0.87
Occipital Lobe3.41 ± 0.95
Parietal Lobe3.47 ± 0.87
Pontine Tegmentum3.63 ± 0.85
Striatum4.45 ± 0.79
Subthalamus3.72 ± 0.25
Temporal Lobe3.36 ± 0.88
Thalamus4.04 ± 0.65
White Matter6.83 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Depdc7CBCerebellum1.47
2.14
Depdc7CTXCerebral cortex2.07
1.93
Depdc7HIPHippocampal region1.72
1.81
Depdc7HPFHippocampal formation2.04
2.12
Depdc7HYHypothalamus2.56
2.31
Depdc7LSXLateral septal complex0.67
0.53
Depdc7MBMidbrain1.31
1.78
Depdc7MYMedulla2.87
3.33
Depdc7OLFOlfactory bulb8.64
8.04
Depdc7PPons3.38
3.97
Depdc7PALPallidum2.52
2.24
Depdc7RHPRetrohippocampal region2.33
2.46
Depdc7sAMYStriatum-like amygdalar nuclei0.63
0.74
Depdc7STRStriatum0.88
0.73
Depdc7STRdStriatum dorsal region0.28
0.27
Depdc7STRvStriatum ventral region2.59
1.89
Depdc7THThalamus0.73
0.8
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018