AutismKB 2.0

Annotation Detail for LONRF1


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Basic Information Top
Gene Symbol:LONRF1 ( FLJ23749,RNF191 )
Gene Full Name: LON peptidase N-terminal domain and ring finger 1
Band: 8p23.1
Quick LinksEntrez ID:91694; OMIM: NA; Uniprot ID:LONF1_HUMAN; ENSEMBL ID: ENSG00000154359; HGNC ID: 26302
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus16 / 56401228
neonate1 / 3109732
infant0 / 236200 
juvenile2 / 5555635
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor7 / 26384526
glioma2 / 10688318
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal84 / 336030724
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer13 / 102680126
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow1 / 4880120
brain11 / 11009899
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye6 / 21105428
heart5 / 8962655
intestine5 / 23447221
kidney3 / 21177714
larynx1 / 2414541
liver4 / 20774319
lung5 / 33697414
lymph0 / 442700 
lymph node9 / 9161098
mammary gland0 / 1532710 
mouth4 / 6705259
muscle1 / 1077159
nerve2 / 15768126
ovary3 / 10205129
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate14 / 18934573
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis18 / 33044254
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P934202
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.28 ± 0.56
Basal Forebrain5.4 ± 0.27
Basal Part of Pons5.16 ± 0.35
Cerebellar Cortex5.71 ± 0.3
Cerebellar Nuclei4.54 ± 0.47
Claustrum5.53 ± 0.45
Epithalamus5.56 ± 0.22
Frontal Lobe5.4 ± 0.47
Globus Pallidus4.63 ± 0.56
Hypothalamus5.17 ± 0.39
Insula5.45 ± 0.22
Limbic Lobe5.61 ± 0.46
Mesencephalon5.38 ± 0.5
Myelencephalon5.32 ± 0.5
Occipital Lobe5.56 ± 0.41
Parietal Lobe5.38 ± 0.44
Pontine Tegmentum5.44 ± 0.51
Striatum5.04 ± 0.47
Subthalamus5.59 ± 1.99
Temporal Lobe5.47 ± 0.43
Thalamus5.46 ± 0.4
White Matter4.85 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lonrf1CBCerebellum14.63
17.25
Lonrf1CTXCerebral cortex66.46
53.9
Lonrf1HIPHippocampal region28.66
40.37
Lonrf1HPFHippocampal formation47.41
54.48
Lonrf1HYHypothalamus8.28
6.45
Lonrf1LSXLateral septal complex28.55
20.31
Lonrf1MBMidbrain15.79
13.82
Lonrf1MYMedulla20.69
22.46
Lonrf1OLFOlfactory bulb47.5
38.27
Lonrf1PPons12.29
12.85
Lonrf1PALPallidum15.04
12.92
Lonrf1RHPRetrohippocampal region83.5
78.47
Lonrf1sAMYStriatum-like amygdalar nuclei33.2
25.17
Lonrf1STRStriatum34.22
23.99
Lonrf1STRdStriatum dorsal region35.38
24.91
Lonrf1STRvStriatum ventral region30.24
19.49
Lonrf1THThalamus57.34
51.84
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018