AutismKB 2.0

Annotation Detail for ACY3


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Basic Information Top
Gene Symbol:ACY3 ( ACY-3,HCBP1,MGC9740 )
Gene Full Name: aspartoacylase (aminocyclase) 3
Band: 11q13.2
Quick LinksEntrez ID:91703; OMIM: NA; Uniprot ID:ACY3_HUMAN; ENSEMBL ID: ENSG00000132744; HGNC ID: 24104
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult7 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal22 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine3 / 23447212
kidney9 / 21177742
larynx0 / 241450 
liver2 / 2077439
lung0 / 3369740 
lymph1 / 4427022
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16596_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.02 ± 0.88
Basal Forebrain3.72 ± 0.48
Basal Part of Pons3.8 ± 0.86
Cerebellar Cortex2.78 ± 0.64
Cerebellar Nuclei4.13 ± 0.69
Claustrum3.45 ± 0.87
Epithalamus4.01 ± 0.83
Frontal Lobe3.2 ± 0.82
Globus Pallidus5.13 ± 0.34
Hypothalamus2.96 ± 1.17
Insula3.29 ± 0.83
Limbic Lobe3.48 ± 0.74
Mesencephalon3.37 ± 0.84
Myelencephalon3.39 ± 0.81
Occipital Lobe3.08 ± 0.8
Parietal Lobe3.48 ± 0.79
Pontine Tegmentum3.31 ± 0.93
Striatum3.92 ± 0.65
Subthalamus3.73 ± 0.53
Temporal Lobe3.39 ± 0.79
Thalamus3.38 ± 0.74
White Matter5.12 ± 0.63
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Acy3CBCerebellum1.19
1.52
Acy3CTXCerebral cortex1.97
1.66
Acy3HIPHippocampal region0.4
0.41
Acy3HPFHippocampal formation0.38
0.4
Acy3HYHypothalamus0.22
0.23
Acy3LSXLateral septal complex0.06
0.03
Acy3MBMidbrain0.48
0.51
Acy3MYMedulla3.2
4.09
Acy3OLFOlfactory bulb4.53
3.08
Acy3PPons1.4
1.22
Acy3PALPallidum1.69
1.3
Acy3RHPRetrohippocampal region0.38
0.4
Acy3sAMYStriatum-like amygdalar nuclei0.81
0.65
Acy3STRStriatum0.59
0.44
Acy3STRdStriatum dorsal region0.6
0.48
Acy3STRvStriatum ventral region0.64
0.39
Acy3THThalamus0.83
0.7
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018