AutismKB 2.0

Annotation Detail for CHMP7


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Basic Information Top
Gene Symbol:CHMP7 ( MGC29816 )
Gene Full Name: CHMP family, member 7
Band: 8p21.3
Quick LinksEntrez ID:91782; OMIM: 611130; Uniprot ID:CHMP7_HUMAN; ENSEMBL ID: ENSG00000147457; HGNC ID: 28439
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst7 / 62319112
fetus51 / 56401290
neonate1 / 3109732
infant2 / 2362084
juvenile3 / 5555653
adult124 / 193912163
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor3 / 3436687
chondrosarcoma13 / 82823156
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor22 / 26384583
glioma9 / 10688384
head and neck tumor8 / 13630258
kidney tumor4 / 6895958
leukemia9 / 9584293
liver tumor5 / 9635951
lung tumor5 / 10312748
lymphoma23 / 71755320
non-neoplasia6 / 9725061
normal239 / 336030771
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer8 / 10268077
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland7 / 33197210
ascites6 / 40015149
bladder3 / 29757100
blood5 / 12347840
bone4 / 7165555
bone marrow0 / 488010 
brain63 / 110098957
cervix4 / 4817183
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye7 / 21105433
heart4 / 8962644
intestine9 / 23447238
kidney18 / 21177784
larynx0 / 241450 
liver11 / 20774352
lung23 / 33697468
lymph19 / 44270429
lymph node15 / 91610163
mammary gland14 / 15327191
mouth5 / 6705274
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta12 / 28082542
prostate19 / 189345100
salivary gland1 / 2015549
skin17 / 21057480
spleen3 / 5395255
stomach0 / 966190 
testis30 / 33044290
thymus12 / 81131147
thyroid3 / 4747363
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212313_at
Cell line Expression level Expression bar
721_B_lymphoblasts155.4
Adipocyte29.85
AdrenalCortex51.55
Adrenalgland95.35
Amygdala53.9
Appendix25.15
AtrioventricularNode25.45
BDCA4+_DentriticCells114.65
Bonemarrow41.5
BronchialEpithelialCells27.85
CD105+_Endothelial102.15
CD14+_Monocytes171.3
CD19+_BCells(neg._sel.)743.25
CD33+_Myeloid130.05
CD34+104.8
CD4+_Tcells1041.35
CD56+_NKCells164.5
CD71+_EarlyErythroid85
CD8+_Tcells729.7
CardiacMyocytes57.7
Caudatenucleus25.05
Cerebellum43.35
CerebellumPeduncles54.45
CiliaryGanglion36.3
CingulateCortex43
Colorectaladenocarcinoma93.3
DorsalRootGanglion27.55
FetalThyroid52.55
Fetalbrain68.55
Fetalliver28.1
Fetallung21.3
GlobusPallidus30.45
Heart76.05
Hypothalamus57.9
Kidney27.95
Leukemia_chronicMyelogenousK-56230.45
Leukemia_promyelocytic-HL-6076.1
Leukemialymphoblastic(MOLT-4)28.85
Liver53.1
Lung66.15
Lymphnode86.05
Lymphoma_burkitts(Daudi)141.5
Lymphoma_burkitts(Raji)109.5
MedullaOblongata27.95
OccipitalLobe40.9
OlfactoryBulb23.55
Ovary20.6
Pancreas41.65
PancreaticIslet44.25
ParietalLobe63.15
Pituitary41.4
Placenta37.5
Pons38.1
PrefrontalCortex62.55
Prostate96.9
Salivarygland33.15
SkeletalMuscle68.65
Skin30.6
SmoothMuscle42.1
Spinalcord48.5
SubthalamicNucleus49.6
SuperiorCervicalGanglion42.3
TemporalLobe61
Testis32.7
TestisGermCell46
TestisIntersitial25
TestisLeydigCell30.85
TestisSeminiferousTubule25.85
Thalamus63.9
Thymus163.15
Thyroid48.25
Tongue34.45
Tonsil97.95
Trachea27.4
TrigeminalGanglion35.65
Uterus34.7
UterusCorpus19.4
WholeBlood123.45
Wholebrain74.05
colon35.05
pineal_day129.38
pineal_night137.14
retina81.25
small_intestine47.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P70220
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.14 ± 0.33
Basal Forebrain6.89 ± 0.28
Basal Part of Pons7.2 ± 0.31
Cerebellar Cortex6.96 ± 0.32
Cerebellar Nuclei7.21 ± 0.52
Claustrum7.24 ± 0.44
Epithalamus6.84 ± 0.27
Frontal Lobe7.09 ± 0.39
Globus Pallidus6.95 ± 0.28
Hypothalamus7.01 ± 0.62
Insula7.06 ± 0.3
Limbic Lobe7.24 ± 0.36
Mesencephalon7.17 ± 0.35
Myelencephalon7.09 ± 0.37
Occipital Lobe7.38 ± 0.34
Parietal Lobe7.18 ± 0.31
Pontine Tegmentum7.19 ± 0.35
Striatum7.09 ± 0.3
Subthalamus7.3 ± 0.18
Temporal Lobe7.07 ± 0.35
Thalamus7.17 ± 0.3
White Matter7.18 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Chmp7CBCerebellum15.11
20.82
Chmp7CTXCerebral cortex60.17
52.25
Chmp7HIPHippocampal region29.59
38.39
Chmp7HPFHippocampal formation31.28
35.01
Chmp7HYHypothalamus4.36
4.09
Chmp7LSXLateral septal complex6.92
5.96
Chmp7MBMidbrain5.51
6.52
Chmp7MYMedulla6.27
9.74
Chmp7OLFOlfactory bulb32.53
31.01
Chmp7PPons5.55
8.72
Chmp7PALPallidum11.07
11.72
Chmp7RHPRetrohippocampal region35.76
31.19
Chmp7sAMYStriatum-like amygdalar nuclei10.22
8.38
Chmp7STRStriatum11.86
9.66
Chmp7STRdStriatum dorsal region11.83
9.85
Chmp7STRvStriatum ventral region15.7
11.66
Chmp7THThalamus17.98
17.81
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CHMP7_HUMAN_83 17 83 99 KGSVPLGLATVLQDLLR PRIDE
CHMP7_HUMAN_84 16 84 99 GSVPLGLATVLQDLLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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