AutismKB 2.0

Annotation Detail for OSMR


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Basic Information Top
Gene Symbol:OSMR ( MGC150626,MGC150627,MGC75127,OSMRB )
Gene Full Name: oncostatin M receptor
Band: 5p13.1
Quick LinksEntrez ID:9180; OMIM: 601743; Uniprot ID:OSMR_HUMAN; ENSEMBL ID: ENSG00000145623; HGNC ID: 8507
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus21 / 56401237
neonate1 / 3109732
infant0 / 236200 
juvenile5 / 5555689
adult103 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor6 / 9417863
cervical tumor1 / 3436629
chondrosarcoma12 / 82823144
colorectal tumor1 / 1142468
esophageal tumor4 / 17290231
gastrointestinal tumor5 / 11936941
germ cell tumor4 / 26384515
glioma4 / 10688337
head and neck tumor11 / 13630280
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor6 / 9635962
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia15 / 97250154
normal119 / 336030735
ovarian tumor3 / 7668239
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder2 / 2975767
blood0 / 1234780 
bone8 / 71655111
bone marrow0 / 488010 
brain25 / 110098922
cervix1 / 4817120
connective tissue27 / 149255180
ear1 / 1621261
embryonic tissue3 / 21572213
esophagus5 / 20209247
eye5 / 21105423
heart2 / 8962622
intestine1 / 2344724
kidney9 / 21177742
larynx7 / 24145289
liver9 / 20774343
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland13 / 15327184
mouth0 / 670520 
muscle3 / 10771527
nerve1 / 1576863
ovary3 / 10205129
pancreas19 / 21481288
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta18 / 28082564
prostate8 / 18934542
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach6 / 9661962
testis6 / 33044218
thymus8 / 8113198
thyroid1 / 4747321
tonsil0 / 169990 
trachea13 / 52413248
umbilical cord0 / 136800 
uterus10 / 23287842
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205729_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.5
Adipocyte9.3
AdrenalCortex7.6
Adrenalgland6.2
Amygdala6.4
Appendix6.95
AtrioventricularNode8.8
BDCA4+_DentriticCells6.25
Bonemarrow6.35
BronchialEpithelialCells6.6
CD105+_Endothelial6.3
CD14+_Monocytes6.65
CD19+_BCells(neg._sel.)6.7
CD33+_Myeloid8.1
CD34+8
CD4+_Tcells6.65
CD56+_NKCells7.25
CD71+_EarlyErythroid5.95
CD8+_Tcells6.1
CardiacMyocytes58.5
Caudatenucleus5.7
Cerebellum5.15
CerebellumPeduncles7.4
CiliaryGanglion6.6
CingulateCortex6.45
Colorectaladenocarcinoma6.3
DorsalRootGanglion5.5
FetalThyroid6.15
Fetalbrain6.25
Fetalliver5.5
Fetallung6.1
GlobusPallidus4.7
Heart8.15
Hypothalamus6.9
Kidney5.4
Leukemia_chronicMyelogenousK-5625.7
Leukemia_promyelocytic-HL-605.6
Leukemialymphoblastic(MOLT-4)5.1
Liver8.5
Lung6.95
Lymphnode5.45
Lymphoma_burkitts(Daudi)8.05
Lymphoma_burkitts(Raji)8.9
MedullaOblongata5.8
OccipitalLobe5.65
OlfactoryBulb4.9
Ovary9.25
Pancreas5.25
PancreaticIslet6.8
ParietalLobe7.05
Pituitary7.35
Placenta15.95
Pons6.15
PrefrontalCortex7.85
Prostate7.2
Salivarygland5.25
SkeletalMuscle8.45
Skin7.4
SmoothMuscle98.3
Spinalcord6.7
SubthalamicNucleus6
SuperiorCervicalGanglion12
TemporalLobe5.8
Testis5.4
TestisGermCell5.25
TestisIntersitial5.4
TestisLeydigCell6.3
TestisSeminiferousTubule5.4
Thalamus6.45
Thymus5
Thyroid7.65
Tongue6.45
Tonsil6.2
Trachea5.3
TrigeminalGanglion6.85
Uterus5.05
UterusCorpus5.7
WholeBlood6.85
Wholebrain5.15
colon6.4
pineal_day7.94
pineal_night7.72
retina7.675
small_intestine6.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P156289
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.43 ± 1.11
Basal Forebrain1.7 ± 0.49
Basal Part of Pons1.95 ± 0.7
Cerebellar Cortex1.74 ± 0.87
Cerebellar Nuclei2.37 ± 0.74
Claustrum2.59 ± 1.07
Epithalamus2.61 ± 0.74
Frontal Lobe1.98 ± 0.89
Globus Pallidus3.18 ± 0.67
Hypothalamus2.11 ± 0.8
Insula1.79 ± 0.81
Limbic Lobe2.09 ± 0.86
Mesencephalon2.27 ± 0.83
Myelencephalon2.22 ± 0.83
Occipital Lobe2.11 ± 0.81
Parietal Lobe2.16 ± 0.97
Pontine Tegmentum2.21 ± 0.94
Striatum2.68 ± 0.79
Subthalamus2.07 ± 0.38
Temporal Lobe2.06 ± 0.9
Thalamus2.16 ± 0.79
White Matter2.14 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
OsmrCBCerebellum0.37
0.61
OsmrCTXCerebral cortex0.39
0.45
OsmrHIPHippocampal region0.96
1.2
OsmrHPFHippocampal formation0.87
1.2
OsmrHYHypothalamus0.11
0.09
OsmrLSXLateral septal complex0.12
0.17
OsmrMBMidbrain0.34
0.61
OsmrMYMedulla2.4
2.89
OsmrOLFOlfactory bulb0.39
0.83
OsmrPPons0.19
0.18
OsmrPALPallidum0.21
0.4
OsmrRHPRetrohippocampal region0.79
1.19
OsmrsAMYStriatum-like amygdalar nuclei0.68
0.48
OsmrSTRStriatum0.4
0.47
OsmrSTRdStriatum dorsal region0.5
0.65
OsmrSTRvStriatum ventral region0.05
0.07
OsmrTHThalamus0.49
0.65
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
OSMR_HUMAN_0 0 0 0 TYQSEVLAERLPLTPVSLK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018