AutismKB 2.0

Annotation Detail for OSMR


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Basic Information Top
Gene Symbol:OSMR ( MGC150626,MGC150627,MGC75127,OSMRB )
Gene Full Name: oncostatin M receptor
Band: 5p13.1
Quick LinksEntrez ID:9180; OMIM: 601743; Uniprot ID:OSMR_HUMAN; ENSEMBL ID: ENSG00000145623; HGNC ID: 8507
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus21 / 56401237
neonate1 / 3109732
infant0 / 236200 
juvenile5 / 5555689
adult103 / 193912153
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205729_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.5
Adipocyte9.3
AdrenalCortex7.6
Adrenalgland6.2
Amygdala6.4
Appendix6.95
AtrioventricularNode8.8
BDCA4+_DentriticCells6.25
Bonemarrow6.35
BronchialEpithelialCells6.6
CD105+_Endothelial6.3
CD14+_Monocytes6.65
CD19+_BCells(neg._sel.)6.7
CD33+_Myeloid8.1
CD34+8
CD4+_Tcells6.65
CD56+_NKCells7.25
CD71+_EarlyErythroid5.95
CD8+_Tcells6.1
CardiacMyocytes58.5
Caudatenucleus5.7
Cerebellum5.15
CerebellumPeduncles7.4
CiliaryGanglion6.6
CingulateCortex6.45
Colorectaladenocarcinoma6.3
DorsalRootGanglion5.5
FetalThyroid6.15
Fetalbrain6.25
Fetalliver5.5
Fetallung6.1
GlobusPallidus4.7
Heart8.15
Hypothalamus6.9
Kidney5.4
Leukemia_chronicMyelogenousK-5625.7
Leukemia_promyelocytic-HL-605.6
Leukemialymphoblastic(MOLT-4)5.1
Liver8.5
Lung6.95
Lymphnode5.45
Lymphoma_burkitts(Daudi)8.05
Lymphoma_burkitts(Raji)8.9
MedullaOblongata5.8
OccipitalLobe5.65
OlfactoryBulb4.9
Ovary9.25
Pancreas5.25
PancreaticIslet6.8
ParietalLobe7.05
Pituitary7.35
Placenta15.95
Pons6.15
PrefrontalCortex7.85
Prostate7.2
Salivarygland5.25
SkeletalMuscle8.45
Skin7.4
SmoothMuscle98.3
Spinalcord6.7
SubthalamicNucleus6
SuperiorCervicalGanglion12
TemporalLobe5.8
Testis5.4
TestisGermCell5.25
TestisIntersitial5.4
TestisLeydigCell6.3
TestisSeminiferousTubule5.4
Thalamus6.45
Thymus5
Thyroid7.65
Tongue6.45
Tonsil6.2
Trachea5.3
TrigeminalGanglion6.85
Uterus5.05
UterusCorpus5.7
WholeBlood6.85
Wholebrain5.15
colon6.4
pineal_day7.94
pineal_night7.72
retina7.675
small_intestine6.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P156289
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.43 ± 1.11
Basal Forebrain1.7 ± 0.49
Basal Part of Pons1.95 ± 0.7
Cerebellar Cortex1.74 ± 0.87
Cerebellar Nuclei2.37 ± 0.74
Claustrum2.59 ± 1.07
Epithalamus2.61 ± 0.74
Frontal Lobe1.98 ± 0.89
Globus Pallidus3.18 ± 0.67
Hypothalamus2.11 ± 0.8
Insula1.79 ± 0.81
Limbic Lobe2.09 ± 0.86
Mesencephalon2.27 ± 0.83
Myelencephalon2.22 ± 0.83
Occipital Lobe2.11 ± 0.81
Parietal Lobe2.16 ± 0.97
Pontine Tegmentum2.21 ± 0.94
Striatum2.68 ± 0.79
Subthalamus2.07 ± 0.38
Temporal Lobe2.06 ± 0.9
Thalamus2.16 ± 0.79
White Matter2.14 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
OsmrCBCerebellum0.37
0.61
OsmrCTXCerebral cortex0.39
0.45
OsmrHIPHippocampal region0.96
1.2
OsmrHPFHippocampal formation0.87
1.2
OsmrHYHypothalamus0.11
0.09
OsmrLSXLateral septal complex0.12
0.17
OsmrMBMidbrain0.34
0.61
OsmrMYMedulla2.4
2.89
OsmrOLFOlfactory bulb0.39
0.83
OsmrPPons0.19
0.18
OsmrPALPallidum0.21
0.4
OsmrRHPRetrohippocampal region0.79
1.19
OsmrsAMYStriatum-like amygdalar nuclei0.68
0.48
OsmrSTRStriatum0.4
0.47
OsmrSTRdStriatum dorsal region0.5
0.65
OsmrSTRvStriatum ventral region0.05
0.07
OsmrTHThalamus0.49
0.65
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
OSMR_HUMAN_0 0 0 0 TYQSEVLAERLPLTPVSLK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018