Annotation Detail for MYLK3
Basic Information Top
| Gene Symbol: | MYLK3 ( MGC126319,MGC126320,MLCK,MLCK2,caMLCK ) |
|---|---|
| Gene Full Name: | myosin light chain kinase 3 |
| Band: | 16q11.2 |
| Quick Links | Entrez ID:91807; OMIM: 612147; Uniprot ID:MYLK3_HUMAN; ENSEMBL ID: ENSG00000140795; HGNC ID: 29826 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.130465
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 8 / 564012 | 14 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 9 / 1939121 | 4 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 25 / 3360307 | 7 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 2 / 1100989 | 1 |  |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 1 / 215722 | 4 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 10 / 89626 | 111 |  |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 5 / 330442 | 15 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_28_PI416408490
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 1.81 ± 1.15 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.36 ± 0.42 | |
| Basal Part of Pons | 1.24 ± 0.74 | |
| Cerebellar Cortex | 1.48 ± 1.04 | |
| Cerebellar Nuclei | 1.87 ± 0.93 | |
| Claustrum | 2.5 ± 1.03 | |
| Epithalamus | 1.8 ± 0.9 | |
| Frontal Lobe | 1.35 ± 0.81 | |
| Globus Pallidus | 1.79 ± 0.48 | |
| Hypothalamus | 1.43 ± 0.69 | |
| Insula | 1.25 ± 0.78 | |
| Limbic Lobe | 1.48 ± 0.89 | |
| Mesencephalon | 1.57 ± 0.91 | |
| Myelencephalon | 1.54 ± 0.9 | |
| Occipital Lobe | 1.61 ± 0.98 | |
| Parietal Lobe | 1.54 ± 1.04 | |
| Pontine Tegmentum | 1.46 ± 0.84 | |
| Striatum | 1.54 ± 0.78 | |
| Subthalamus | 1.56 ± 0.96 | |
| Temporal Lobe | 1.31 ± 0.9 | |
| Thalamus | 1.38 ± 0.78 | |
| White Matter | 1.42 ± 0.23 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| D830007F02Rik | CB | Cerebellum | 6.74 | |
| 7.3 | | |||
| D830007F02Rik | CTX | Cerebral cortex | 12.59 | |
| 9.7 | | |||
| D830007F02Rik | HIP | Hippocampal region | 14.98 | |
| 17.56 | | |||
| D830007F02Rik | HPF | Hippocampal formation | 10.05 | |
| 10.57 | | |||
| D830007F02Rik | HY | Hypothalamus | 4.06 | |
| 3.54 | | |||
| D830007F02Rik | LSX | Lateral septal complex | 1.48 | |
| 1.49 | | |||
| D830007F02Rik | MB | Midbrain | 3.06 | |
| 3.06 | | |||
| D830007F02Rik | MY | Medulla | 6.71 | |
| 8.75 | | |||
| D830007F02Rik | OLF | Olfactory bulb | 7.46 | |
| 5.44 | | |||
| D830007F02Rik | P | Pons | 4.85 | |
| 5.6 | | |||
| D830007F02Rik | PAL | Pallidum | 1.65 | |
| 1.46 | | |||
| D830007F02Rik | RHP | Retrohippocampal region | 4.14 | |
| 3.45 | | |||
| D830007F02Rik | sAMY | Striatum-like amygdalar nuclei | 3.66 | |
| 2.82 | | |||
| D830007F02Rik | STR | Striatum | 1.76 | |
| 1.62 | | |||
| D830007F02Rik | STRd | Striatum dorsal region | 1.63 | |
| 1.56 | | |||
| D830007F02Rik | STRv | Striatum ventral region | 1.36 | |
| 1.32 | | |||
| D830007F02Rik | TH | Thalamus | 6.46 | |
| 5.3 | |