AutismKB 2.0

Annotation Detail for WDR20


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Basic Information Top
Gene Symbol:WDR20 ( DMR,FLJ33659,MGC33177,MGC33183 )
Gene Full Name: WD repeat domain 20
Band: 14q32.31
Quick LinksEntrez ID:91833; OMIM: NA; Uniprot ID:WDR20_HUMAN; ENSEMBL ID: ENSG00000140153; HGNC ID: 19667
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus54 / 56401295
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult88 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor10 / 26384537
glioma7 / 10688365
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia11 / 95842114
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal209 / 336030762
ovarian tumor3 / 7668239
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood6 / 12347848
bone2 / 7165527
bone marrow2 / 4880140
brain75 / 110098968
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye9 / 21105442
heart1 / 8962611
intestine7 / 23447229
kidney6 / 21177728
larynx1 / 2414541
liver2 / 2077439
lung11 / 33697432
lymph0 / 442700 
lymph node7 / 9161076
mammary gland11 / 15327171
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary4 / 10205139
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta9 / 28082532
prostate6 / 18934531
salivary gland0 / 201550 
skin6 / 21057428
spleen3 / 5395255
stomach4 / 9661941
testis28 / 33044284
thymus5 / 8113161
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus10 / 23287842
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10416_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.53 ± 0.41
Basal Forebrain7.63 ± 0.35
Basal Part of Pons7.34 ± 0.28
Cerebellar Cortex7.69 ± 0.22
Cerebellar Nuclei7.63 ± 0.39
Claustrum7.35 ± 0.34
Epithalamus7.08 ± 0.57
Frontal Lobe7.25 ± 0.45
Globus Pallidus8.04 ± 0.24
Hypothalamus7.15 ± 0.47
Insula7.17 ± 0.35
Limbic Lobe7.46 ± 0.36
Mesencephalon7.54 ± 0.43
Myelencephalon7.43 ± 0.5
Occipital Lobe7.66 ± 0.39
Parietal Lobe7.46 ± 0.45
Pontine Tegmentum7.46 ± 0.39
Striatum7.55 ± 0.53
Subthalamus7.59 ± 0.08
Temporal Lobe7.26 ± 0.37
Thalamus7.47 ± 0.28
White Matter8.86 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdr20bCBCerebellum36.72
51.09
Wdr20bCTXCerebral cortex53.63
39.99
Wdr20bHIPHippocampal region39.06
48.27
Wdr20bHPFHippocampal formation43.53
44.48
Wdr20bHYHypothalamus26.63
23.88
Wdr20bLSXLateral septal complex23.15
16.16
Wdr20bMBMidbrain33.95
32.84
Wdr20bMYMedulla35.3
40
Wdr20bOLFOlfactory bulb49.36
41.08
Wdr20bPPons28.75
32.86
Wdr20bPALPallidum30.05
26.91
Wdr20bRHPRetrohippocampal region51.29
40.68
Wdr20bsAMYStriatum-like amygdalar nuclei30.53
21.65
Wdr20bSTRStriatum26.31
19.3
Wdr20bSTRdStriatum dorsal region24.56
18.88
Wdr20bSTRvStriatum ventral region30.93
20.09
Wdr20bTHThalamus34.55
31.96
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018