AutismKB 2.0

Annotation Detail for SLC16A7


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Basic Information Top
Gene Symbol:SLC16A7 ( MCT2 )
Gene Full Name: solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
Band: 12q14.1
Quick LinksEntrez ID:9194; OMIM: 603654; Uniprot ID:MOT2_HUMAN; ENSEMBL ID: ENSG00000118596; HGNC ID: 10928
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult6 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal30 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney8 / 21177737
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis15 / 33044245
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210807_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.25
Adipocyte6.95
AdrenalCortex7.3
Adrenalgland5.5
Amygdala6.55
Appendix7
AtrioventricularNode6.2
BDCA4+_DentriticCells12.65
Bonemarrow6.7
BronchialEpithelialCells5.9
CD105+_Endothelial6.35
CD14+_Monocytes7.05
CD19+_BCells(neg._sel.)6.75
CD33+_Myeloid9
CD34+7.8
CD4+_Tcells9.25
CD56+_NKCells14.2
CD71+_EarlyErythroid6
CD8+_Tcells9.25
CardiacMyocytes8.7
Caudatenucleus5.6
Cerebellum5.1
CerebellumPeduncles7.45
CiliaryGanglion5.2
CingulateCortex6.55
Colorectaladenocarcinoma6.25
DorsalRootGanglion5.6
FetalThyroid6.2
Fetalbrain5.95
Fetalliver5.5
Fetallung4.75
GlobusPallidus4.95
Heart9.2
Hypothalamus6.5
Kidney5.35
Leukemia_chronicMyelogenousK-5625.6
Leukemia_promyelocytic-HL-605.5
Leukemialymphoblastic(MOLT-4)4.8
Liver8.55
Lung6.75
Lymphnode5.1
Lymphoma_burkitts(Daudi)8.15
Lymphoma_burkitts(Raji)9.5
MedullaOblongata5.55
OccipitalLobe5.5
OlfactoryBulb4.9
Ovary4.65
Pancreas6
PancreaticIslet7.1
ParietalLobe7
Pituitary7.85
Placenta6.15
Pons6.3
PrefrontalCortex7.4
Prostate7.2
Salivarygland5.2
SkeletalMuscle8.4
Skin5.6
SmoothMuscle7
Spinalcord6.6
SubthalamicNucleus5.9
SuperiorCervicalGanglion8.1
TemporalLobe5.95
Testis5.35
TestisGermCell6.5
TestisIntersitial6.25
TestisLeydigCell6.6
TestisSeminiferousTubule5.35
Thalamus6.55
Thymus4.7
Thyroid7.85
Tongue6.6
Tonsil6.2
Trachea5.5
TrigeminalGanglion7.3
Uterus5
UterusCorpus5.85
WholeBlood6.8
Wholebrain4.95
colon6.25
pineal_day8.18
pineal_night8.58
retina7.525
small_intestine5.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P117059
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4 ± 0.73
Basal Forebrain3.34 ± 0.37
Basal Part of Pons4.68 ± 0.36
Cerebellar Cortex4.34 ± 0.44
Cerebellar Nuclei4.15 ± 0.5
Claustrum3.44 ± 0.69
Epithalamus3.19 ± 0.76
Frontal Lobe3.97 ± 0.62
Globus Pallidus2.69 ± 0.5
Hypothalamus3.31 ± 0.55
Insula3.84 ± 0.55
Limbic Lobe3.94 ± 0.65
Mesencephalon3.8 ± 0.77
Myelencephalon3.75 ± 0.65
Occipital Lobe4.41 ± 0.53
Parietal Lobe4.14 ± 0.59
Pontine Tegmentum3.96 ± 0.63
Striatum2.94 ± 0.69
Subthalamus3.59 ± 0.65
Temporal Lobe3.99 ± 0.61
Thalamus3.8 ± 0.64
White Matter3.35 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slc16a7CBCerebellum2.36
4.57
Slc16a7CTXCerebral cortex4.43
3.22
Slc16a7HIPHippocampal region4.89
5.62
Slc16a7HPFHippocampal formation3.4
3.65
Slc16a7HYHypothalamus0.05
0.34
Slc16a7LSXLateral septal complex0.27
0.24
Slc16a7MBMidbrain0.37
0.55
Slc16a7MYMedulla0.6
1.26
Slc16a7OLFOlfactory bulb4.12
3.84
Slc16a7PPons0.67
1.08
Slc16a7PALPallidum0.13
0.35
Slc16a7RHPRetrohippocampal region1.25
1.23
Slc16a7sAMYStriatum-like amygdalar nuclei0.11
0.07
Slc16a7STRStriatum0.49
0.58
Slc16a7STRdStriatum dorsal region0.63
0.81
Slc16a7STRvStriatum ventral region0.38
0.32
Slc16a7THThalamus0.46
0.71
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018